| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.167592 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.145113 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0833602 |
| PTMA | prothymosin, alpha | 0.0818446 |
| GRB7 | growth factor receptor-bound protein 7 | 0.0786357 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0736995 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0683764 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0648993 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0609853 |
| RPL37A | ribosomal protein L37a | 0.0563454 |
| DSTN | destrin (actin depolymerizing factor) | 0.0541448 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0515186 |
| MSI2 | musashi RNA-binding protein 2 | 0.0510864 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0499674 |
| LASP1 | LIM and SH3 protein 1 | 0.0492305 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.049127 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0490496 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0487741 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0486766 |
| RPS12 | ribosomal protein S12 | 0.0485906 |
| SET | SET nuclear proto-oncogene | 0.0485869 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0483728 |
| KAZN | kazrin, periplakin interacting protein | 0.0483256 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0470444 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.046982 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0458143 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0453113 |
| DENND1A | DENN/MADD domain containing 1A | 0.0437915 |
| DTNA | dystrobrevin, alpha | 0.0431086 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0425428 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.0424702 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0420903 |
| ATP9A | ATPase, class II, type 9A | 0.040832 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.040155 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0389783 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0374286 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0373278 |
| MED13L | mediator complex subunit 13-like | 0.0371615 |
| RBM39 | RNA binding motif protein 39 | 0.0367156 |
| UBAP2 | ubiquitin associated protein 2 | 0.0357858 |
| GOLGB1 | golgin B1 | 0.0357218 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0355538 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0351106 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.034593 |
| POTEF | POTE ankyrin domain family, member F | 0.0344751 |
| INTS6 | integrator complex subunit 6 | 0.0343813 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0338358 |
| GSE1 | Gse1 coiled-coil protein | 0.0335188 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0328768 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0326621 |
| PGR | progesterone receptor | 0.031754 |
| MYO10 | myosin X | 0.0316228 |
| TENM2 | teneurin transmembrane protein 2 | 0.0310861 |
| BRD2 | bromodomain containing 2 | 0.030885 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0307012 |
| RPS3 | ribosomal protein S3 | 0.030644 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.0306403 |
| ACTG1 | actin gamma 1 | 0.0306085 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.030389 |
| RBM47 | RNA binding motif protein 47 | 0.0301398 |
| STXBP4 | syntaxin binding protein 4 | 0.0298023 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.029744 |
| PARD3 | par-3 family cell polarity regulator | 0.0296505 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0295562 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0295431 |
| PHF14 | PHD finger protein 14 | 0.0295334 |
| CCNL1 | cyclin L1 | 0.0294192 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0290508 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0290058 |
| YAP1 | Yes-associated protein 1 | 0.0287934 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0286499 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.0286221 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0285323 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0284851 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0283131 |
| SNX6 | sorting nexin 6 | 0.027637 |
| RPS16 | ribosomal protein S16 | 0.0276314 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.027613 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0275994 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0274917 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.0273532 |
| KIF16B | kinesin family member 16B | 0.0270375 |
| SCFD1 | sec1 family domain containing 1 | 0.0270066 |
| GPC6 | glypican 6 | 0.0269879 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0269295 |
| NKTR | natural killer cell triggering receptor | 0.0268388 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0267399 |
| EFNA5 | ephrin-A5 | 0.0266981 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0266958 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0265163 |
| GRHL2 | grainyhead-like 2 (Drosophila) | 0.0263593 |
| SETX | senataxin | 0.0262816 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0262665 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0262048 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0261174 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0260677 |
| ZNF638 | zinc finger protein 638 | 0.0260348 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0259597 |
| RTN3 | reticulon 3 | 0.025951 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0257984 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.114637 |
| ASPH | aspartate beta-hydroxylase | -0.107807 |
| NTN4 | netrin 4 | -0.0707066 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0680281 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0657169 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.0601406 |
| MYOF | myoferlin | -0.0568174 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0494889 |
| OSMR | oncostatin M receptor | -0.0475511 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0472213 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0470494 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0468386 |
| PGK1 | phosphoglycerate kinase 1 | -0.046745 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0457785 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0456332 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0447004 |
| CLTC | clathrin, heavy chain (Hc) | -0.0437197 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0430649 |
| VMP1 | vacuole membrane protein 1 | -0.0422309 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0415049 |
| ITGB6 | integrin, beta 6 | -0.0413799 |
| SMYD3 | SET and MYND domain containing 3 | -0.0391417 |
| AHR | aryl hydrocarbon receptor | -0.0386943 |
| LOC112694756 | uncharaterized LOC112694756 | -0.036836 |
| SERINC3 | serine incorporator 3 | -0.0343463 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0329283 |
| ZNF217 | zinc finger protein 217 | -0.032814 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0320952 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0316243 |
| SGMS1 | sphingomyelin synthase 1 | -0.0314498 |
| FAM13A | family with sequence similarity 13, member A | -0.0308505 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.03031 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0302638 |
| S100A14 | S100 calcium binding protein A14 | -0.0298678 |
| LDHA | lactate dehydrogenase A | -0.0296899 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0289681 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0287641 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0287204 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0286406 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.028487 |
| TMEM45B | transmembrane protein 45B | -0.0283657 |
| KIF5B | kinesin family member 5B | -0.0283431 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.028246 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0281842 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0278298 |
| TMC5 | transmembrane channel-like 5 | -0.0274981 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0272413 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.027073 |
| GLCCI1 | glucocorticoid induced 1 | -0.0269545 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0269374 |
| FGB | fibrinogen beta chain | -0.0266167 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0264863 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0263816 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0262811 |
| SPTSSB | serine palmitoyltransferase, small subunit B | -0.0258942 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0257523 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0254896 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0253975 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.024879 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0244649 |
| ANXA2 | annexin A2 | -0.0239121 |
| EGFR | epidermal growth factor receptor | -0.0238398 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0233174 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0232417 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.023175 |
| APP | amyloid beta (A4) precursor protein | -0.0228039 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0225428 |
| DUSP4 | dual specificity phosphatase 4 | -0.0225085 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0224464 |
| AREG | amphiregulin | -0.0223989 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0220955 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0220266 |
| OGA | O-GlcNAcase | -0.0219771 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0217815 |
| SDCBP | syndecan binding protein (syntenin) | -0.0216192 |
| RESF1 | retroelement silencing factor 1 | -0.0211243 |
| TMEM123 | transmembrane protein 123 | -0.0209135 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.020819 |
| CENPF | centromere protein F, 350/400kDa | -0.0207204 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0205981 |
| TMSB10 | thymosin beta 10 | -0.0205732 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0204463 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.020079 |
| RACK1 | receptor for activated C kinase 1 | -0.0200011 |
| USP53 | ubiquitin specific peptidase 53 | -0.0199425 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0199367 |
| ACTN1 | actinin, alpha 1 | -0.0198604 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0193747 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0192545 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0189787 |
| PKM | pyruvate kinase, muscle | -0.0189322 |
| AHNAK | AHNAK nucleoprotein | -0.0186539 |
| H1-0 | H1.0 linker histone | -0.0186232 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0186114 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0185485 |
| ABHD17C | abhydrolase domain containing 17C | -0.0183716 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0183111 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0182161 |
| TMEM165 | transmembrane protein 165 | -0.0181118 |
| RPL19 | ribosomal protein L19 | -0.017952 |
