| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.148947 |
| NDRG1 | N-myc downstream regulated 1 | 0.130516 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.09539 |
| CD109 | CD109 molecule | 0.0945634 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0892524 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0865825 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0844084 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0793931 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0768498 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0765197 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0665264 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0661643 |
| FMNL2 | formin-like 2 | 0.0661239 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0652369 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0638887 |
| NUP58 | nucleoporin 58 | 0.0636616 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0542112 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0539958 |
| PHF21A | PHD finger protein 21A | 0.0513652 |
| CDC73 | cell division cycle 73 | 0.0507792 |
| RNF145 | ring finger protein 145 | 0.0503276 |
| CABIN1 | calcineurin binding protein 1 | 0.0480765 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0474476 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0464783 |
| COPA | coatomer protein complex, subunit alpha | 0.0457443 |
| ZNF292 | zinc finger protein 292 | 0.0454196 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.044532 |
| SETD5 | SET domain containing 5 | 0.0442184 |
| PTK2 | protein tyrosine kinase 2 | 0.0430645 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0427996 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0415041 |
| MEF2A | myocyte enhancer factor 2A | 0.0414614 |
| NLGN1 | neuroligin 1 | 0.0408974 |
| FOXJ3 | forkhead box J3 | 0.0407198 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0391806 |
| RNF150 | ring finger protein 150 | 0.039111 |
| CCNL1 | cyclin L1 | 0.0386916 |
| RBM39 | RNA binding motif protein 39 | 0.038387 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0381025 |
| HELZ | helicase with zinc finger | 0.0378888 |
| NBAS | neuroblastoma amplified sequence | 0.0369549 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0367235 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0366149 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0357835 |
| ADM | adrenomedullin | 0.0357374 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0351151 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.035082 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0342434 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0341773 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0341403 |
| FLNB | filamin B, beta | 0.0339269 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0337179 |
| GPC6 | glypican 6 | 0.0327195 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0327094 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0325052 |
| FOSL1 | FOS-like antigen 1 | 0.0319795 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0319062 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0316622 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0311791 |
| SSBP3 | single stranded DNA binding protein 3 | 0.030972 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0307876 |
| AFDN | afadin, adherens junction formation factor | 0.0299533 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0299149 |
| VMP1 | vacuole membrane protein 1 | 0.0298725 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0293517 |
| SRPK2 | SRSF protein kinase 2 | 0.0293269 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.029153 |
| RAD51B | RAD51 paralog B | 0.0288573 |
| CDK19 | cyclin-dependent kinase 19 | 0.0288455 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0287129 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0286263 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0286016 |
| ZC3H7A | zinc finger CCCH-type containing 7A | 0.0285617 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0283916 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0283007 |
| ZNF638 | zinc finger protein 638 | 0.028144 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0270414 |
| CUL3 | cullin 3 | 0.0270093 |
| MCL1 | myeloid cell leukemia 1 | 0.0269616 |
| FBXO7 | F-box protein 7 | 0.0266786 |
| SNX13 | sorting nexin 13 | 0.0265506 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0265108 |
| PRELID2 | PRELI domain containing 2 | 0.0262712 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.02623 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0262299 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0261419 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0260389 |
| PCBP2 | poly(rC) binding protein 2 | 0.0256265 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0251411 |
| RFX7 | regulatory factor X, 7 | 0.0249481 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.024203 |
| ARRDC3 | arrestin domain containing 3 | 0.0239161 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.02391 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0236667 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0236162 |
| COG5 | component of oligomeric golgi complex 5 | 0.0233806 |
| GOLGA4 | golgin A4 | 0.0232213 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0230882 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0228113 |
| AHR | aryl hydrocarbon receptor | 0.0228068 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.216852 |
| VGF | VGF nerve growth factor inducible | -0.178186 |
| VIM | vimentin | -0.169826 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.146981 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.144642 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.127154 |
| FN1 | fibronectin 1 | -0.109638 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.105244 |
| FMN1 | formin 1 | -0.103284 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0936072 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.092446 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.081212 |
| FRMD4A | FERM domain containing 4A | -0.0801722 |
| NAV3 | neuron navigator 3 | -0.0661737 |
| ACTG1 | actin gamma 1 | -0.0658735 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0614497 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0604051 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0583651 |
| AHNAK | AHNAK nucleoprotein | -0.0581298 |
| CALU | calumenin | -0.0555055 |
| S100A6 | S100 calcium binding protein A6 | -0.0549099 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0545943 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0527166 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0514734 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0511945 |
| EHBP1 | EH domain binding protein 1 | -0.0505904 |
| TMSB10 | thymosin beta 10 | -0.0478665 |
| TNNC1 | troponin C type 1 (slow) | -0.0465462 |
| CANX | calnexin | -0.0462136 |
| CDK14 | cyclin-dependent kinase 14 | -0.0444391 |
| TMEM123 | transmembrane protein 123 | -0.0443235 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0431582 |
| DCT | dopachrome tautomerase | -0.0422555 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0410072 |
| HMCN1 | hemicentin 1 | -0.0401074 |
| ENO1 | enolase 1, (alpha) | -0.0394016 |
| IER3 | immediate early response 3 | -0.0393497 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0375341 |
| DST | dystonin | -0.036213 |
| CUX1 | cut-like homeobox 1 | -0.0340338 |
| LMNA | lamin A/C | -0.0339217 |
| RRBP1 | ribosome binding protein 1 | -0.0335073 |
| OSMR | oncostatin M receptor | -0.0327067 |
| NAV1 | neuron navigator 1 | -0.0313649 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0311799 |
| LAMB1 | laminin, beta 1 | -0.0311419 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0305382 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0301975 |
| PDE10A | phosphodiesterase 10A | -0.0283664 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0279427 |
| HMGA2 | high mobility group AT-hook 2 | -0.0277579 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0275706 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0274439 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0273425 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0270107 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0269908 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0255495 |
| FRMD5 | FERM domain containing 5 | -0.0250135 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0248446 |
| CENPF | centromere protein F, 350/400kDa | -0.0245458 |
| SFTPA2 | surfactant protein A2 | -0.0243428 |
| CCND1 | cyclin D1 | -0.0239927 |
| CD44 | CD44 molecule (Indian blood group) | -0.0239795 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0238598 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.023446 |
| RPLP1 | ribosomal protein, large, P1 | -0.0234036 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.023253 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0232311 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0230296 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0229562 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0227071 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0225321 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0224364 |
| SMYD3 | SET and MYND domain containing 3 | -0.0222279 |
| CAVIN1 | caveolae associated protein 1 | -0.0219889 |
| FHIT | fragile histidine triad | -0.0219043 |
| NBEA | neurobeachin | -0.0217846 |
| MTDH | metadherin | -0.0217768 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0215712 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0210931 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0210827 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0207979 |
| CD63 | CD63 molecule | -0.0207657 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0205722 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0204717 |
| S100A9 | S100 calcium binding protein A9 | -0.0202878 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0200971 |
| PGK1 | phosphoglycerate kinase 1 | -0.0200887 |
| MAP1B | microtubule-associated protein 1B | -0.0199203 |
| SCFD2 | sec1 family domain containing 2 | -0.0198461 |
| LYST | lysosomal trafficking regulator | -0.0198161 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0197103 |
| MAP4 | microtubule-associated protein 4 | -0.0196728 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.01963 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0195472 |
| NRCAM | neuronal cell adhesion molecule | -0.0194752 |
| JAZF1 | JAZF zinc finger 1 | -0.0192718 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0192308 |
| ATM | ATM serine/threonine kinase | -0.0191207 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0190184 |
