| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.380404 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0997573 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0989045 |
| LAMB3 | laminin, beta 3 | 0.0961749 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0933826 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0923823 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0918338 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0898043 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0768908 |
| CP | ceruloplasmin (ferroxidase) | 0.0753471 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0745034 |
| SPAG9 | sperm associated antigen 9 | 0.0716869 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.069952 |
| B2M | beta-2-microglobulin | 0.0683348 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0676777 |
| LDHA | lactate dehydrogenase A | 0.066291 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0655538 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0641106 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.063759 |
| FAM13A | family with sequence similarity 13, member A | 0.0631908 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0614422 |
| UBC | ubiquitin C | 0.0594147 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0591294 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0587952 |
| DTNA | dystrobrevin, alpha | 0.0584662 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0584517 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0573117 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0566028 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0556262 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.054779 |
| HLA-B | major histocompatibility complex, class I, B | 0.0544309 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0526956 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.052017 |
| APP | amyloid beta (A4) precursor protein | 0.0513674 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0512203 |
| APOL1 | apolipoprotein L, 1 | 0.0507739 |
| PLAU | plasminogen activator, urokinase | 0.049574 |
| HLA-E | major histocompatibility complex, class I, E | 0.0488967 |
| AHNAK | AHNAK nucleoprotein | 0.0488248 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0487222 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0486359 |
| MCU | mitochondrial calcium uniporter | 0.0485852 |
| EZR | ezrin | 0.0474294 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0473522 |
| TMEM165 | transmembrane protein 165 | 0.0472528 |
| JMJD1C | jumonji domain containing 1C | 0.0472063 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0464452 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0462597 |
| ANXA2 | annexin A2 | 0.0461116 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0455314 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0453986 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0449759 |
| PGK1 | phosphoglycerate kinase 1 | 0.0447816 |
| KLF6 | Kruppel-like factor 6 | 0.0446825 |
| RBM39 | RNA binding motif protein 39 | 0.0443869 |
| RIOK3 | RIO kinase 3 | 0.0441286 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.043927 |
| ENO1 | enolase 1, (alpha) | 0.0432159 |
| OGA | O-GlcNAcase | 0.0431654 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.042862 |
| CANX | calnexin | 0.0427426 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0424832 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0421558 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0420256 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0415206 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0413331 |
| BCL2L1 | BCL2-like 1 | 0.0405444 |
| NUMB | numb homolog (Drosophila) | 0.0403697 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0399229 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0397871 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0375088 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0374003 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0371185 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.036497 |
| MYO1E | myosin IE | 0.0363166 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0362337 |
| CCNY | cyclin Y | 0.0360541 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0358436 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0357982 |
| FOXO3 | forkhead box O3 | 0.0357213 |
| RCOR1 | REST corepressor 1 | 0.0357125 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0356906 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0356905 |
| MEF2A | myocyte enhancer factor 2A | 0.0355694 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0355529 |
| CCNL1 | cyclin L1 | 0.0353606 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0353572 |
| PHF3 | PHD finger protein 3 | 0.0352409 |
| ARRDC3 | arrestin domain containing 3 | 0.0348317 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0346754 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0345223 |
| WDR26 | WD repeat domain 26 | 0.03412 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0338822 |
| LOX | lysyl oxidase | 0.0337581 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0337573 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0336198 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0333619 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0333368 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0333336 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0331916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0856001 |
| MT2A | metallothionein 2A | -0.0702866 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0601001 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0569483 |
| PCDH7 | protocadherin 7 | -0.0538769 |
| NRG3 | neuregulin 3 | -0.0402505 |
| RNF213 | ring finger protein 213 | -0.0394689 |
| POTEF | POTE ankyrin domain family, member F | -0.0394581 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0392397 |
| HMGA1 | high mobility group AT-hook 1 | -0.0368256 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.034328 |
| RAD51B | RAD51 paralog B | -0.0312416 |
| TPM1 | tropomyosin 1 (alpha) | -0.0307998 |
| HMGA2 | high mobility group AT-hook 2 | -0.0305334 |
| RPS19 | ribosomal protein S19 | -0.0290086 |
| EGFR | epidermal growth factor receptor | -0.027993 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0276003 |
| FTL | ferritin, light polypeptide | -0.0273735 |
| ACTG1 | actin gamma 1 | -0.02558 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0253463 |
| GLIS3 | GLIS family zinc finger 3 | -0.0234801 |
| DST | dystonin | -0.0232855 |
| RPLP1 | ribosomal protein, large, P1 | -0.0224682 |
| EFNA5 | ephrin-A5 | -0.0216854 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0213982 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0213868 |
| ITGA6 | integrin, alpha 6 | -0.0210614 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0210321 |
| MYOF | myoferlin | -0.020764 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.020726 |
| MT1X | metallothionein 1X | -0.020476 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0204378 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0202774 |
| MMP7 | matrix metallopeptidase 7 | -0.0199766 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.019857 |
| LAMA4 | laminin, alpha 4 | -0.0190205 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0184858 |
| LMO7 | LIM domain 7 | -0.0180426 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0179181 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0176846 |
| UTRN | utrophin | -0.0176664 |
| LAMC2 | laminin, gamma 2 | -0.0176027 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.017377 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0171486 |
| FLNA | filamin A, alpha | -0.0169901 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0167078 |
| BICC1 | BicC family RNA binding protein 1 | -0.0166912 |
| ITGB4 | integrin, beta 4 | -0.0166215 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0165268 |
| CD44 | CD44 molecule (Indian blood group) | -0.0162936 |
| RPS6 | ribosomal protein S6 | -0.0159341 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0157605 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0157118 |
| NCKAP5 | NCK-associated protein 5 | -0.0157087 |
| PFN1 | profilin 1 | -0.0155499 |
| RPS29 | ribosomal protein S29 | -0.015324 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0152385 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0151702 |
| LMNA | lamin A/C | -0.0148076 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0147518 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0147249 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0146219 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0145013 |
| MX2 | MX dynamin-like GTPase 2 | -0.0144043 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0143977 |
| MUC16 | mucin 16, cell surface associated | -0.0143056 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0142889 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0142587 |
| LAMA5 | laminin, alpha 5 | -0.0141434 |
| ACTN4 | actinin, alpha 4 | -0.0141028 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0140997 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0138768 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0136963 |
| CMIP | c-Maf inducing protein | -0.0135676 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0134927 |
| KRT23 | keratin 23, type I | -0.0134867 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0133727 |
| SUMF1 | sulfatase modifying factor 1 | -0.0133553 |
| RPS23 | ribosomal protein S23 | -0.0130628 |
| RPS21 | ribosomal protein S21 | -0.0128969 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0128842 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0127727 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0126085 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0125379 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | -0.0124813 |
| WWOX | WW domain containing oxidoreductase | -0.0124669 |
| KYNU | kynureninase | -0.0123035 |
| PLCB4 | phospholipase C, beta 4 | -0.0122488 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.012215 |
| AGRN | agrin | -0.0121399 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0121203 |
| HDAC4 | histone deacetylase 4 | -0.0120734 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0120406 |
| RASEF | RAS and EF-hand domain containing | -0.011916 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0119035 |
| NABP1 | nucleic acid binding protein 1 | -0.0116974 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0116456 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0115318 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0114718 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0114547 |
