| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.108133 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0873853 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0779699 |
| FNDC3A | fibronectin type III domain containing 3A | 0.071042 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0694311 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.067331 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.065936 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0649965 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0648003 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0619783 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0614649 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0577759 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0566073 |
| RNF149 | ring finger protein 149 | 0.0559226 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.053525 |
| TXNIP | thioredoxin interacting protein | 0.0526508 |
| CCNL1 | cyclin L1 | 0.0500595 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.048204 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0472237 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0452894 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0432983 |
| ABHD2 | abhydrolase domain containing 2 | 0.0417698 |
| MEIS2 | Meis homeobox 2 | 0.0417571 |
| RNF43 | ring finger protein 43 | 0.0415186 |
| EHF | ets homologous factor | 0.0412986 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0410757 |
| RUNX1 | runt-related transcription factor 1 | 0.0408349 |
| IFNGR1 | interferon gamma receptor 1 | 0.04021 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0400698 |
| STK24 | serine/threonine kinase 24 | 0.0398333 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0395471 |
| AHI1 | Abelson helper integration site 1 | 0.0390209 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0387607 |
| PTEN | phosphatase and tensin homolog | 0.038638 |
| B2M | beta-2-microglobulin | 0.038289 |
| CANX | calnexin | 0.0376276 |
| GOLGA4 | golgin A4 | 0.0373215 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0368599 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0367555 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0362445 |
| DSTN | destrin (actin depolymerizing factor) | 0.0361866 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0359478 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0358142 |
| RBM39 | RNA binding motif protein 39 | 0.0351628 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0347224 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0336827 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0333899 |
| SUCO | SUN domain containing ossification factor | 0.0331814 |
| USP3 | ubiquitin specific peptidase 3 | 0.0325419 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0323561 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0322195 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0321296 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0318973 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.031535 |
| SBF2 | SET binding factor 2 | 0.0311887 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0310387 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0309702 |
| COPA | coatomer protein complex, subunit alpha | 0.0303996 |
| NCKAP5 | NCK-associated protein 5 | 0.030366 |
| COG6 | component of oligomeric golgi complex 6 | 0.0303567 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0303301 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0302547 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0299038 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0298127 |
| ZNF148 | zinc finger protein 148 | 0.0298052 |
| DIAPH3 | diaphanous-related formin 3 | 0.0296403 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0292724 |
| UBL3 | ubiquitin-like 3 | 0.0289889 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0289704 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0287143 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0286808 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.028422 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0283814 |
| TMEM263 | transmembrane protein 263 | 0.0276872 |
| ZNF292 | zinc finger protein 292 | 0.0269398 |
| TMEM51 | transmembrane protein 51 | 0.0268291 |
| HELZ | helicase with zinc finger | 0.0267904 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0267247 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0267103 |
| UBAC2 | UBA domain containing 2 | 0.0266022 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.026534 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0264592 |
| TFG | TRK-fused gene | 0.0264086 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0263855 |
| TMEM165 | transmembrane protein 165 | 0.0263266 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0262799 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0262459 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0260848 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0258864 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0258341 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0258168 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0255936 |
| GRAMD2B | GRAM domain containing 2B | 0.0255633 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.02547 |
| TMEM87A | transmembrane protein 87A | 0.0254691 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0253453 |
| RBM26 | RNA binding motif protein 26 | 0.0253303 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | 0.0251345 |
| CALR | calreticulin | 0.0249808 |
| IL20RA | interleukin 20 receptor, alpha | 0.0249658 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.20936 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.177871 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.163823 |
| RNF213 | ring finger protein 213 | -0.161158 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.148803 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.123044 |
| RIGI | RNA sensor RIG-I | -0.122149 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.121498 |
| SP100 | SP100 nuclear antigen | -0.120383 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.115644 |
| NPSR1 | neuropeptide S receptor 1 | -0.109293 |
| PLSCR2 | phospholipid scramblase 2 | -0.106565 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.105321 |
| ANXA2 | annexin A2 | -0.0982779 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0937045 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.090903 |
| SQSTM1 | sequestosome 1 | -0.083986 |
| MX2 | MX dynamin-like GTPase 2 | -0.0783499 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0768596 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0753517 |
| XAF1 | XIAP associated factor 1 | -0.0746921 |
| MX1 | MX dynamin-like GTPase 1 | -0.0724895 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0685367 |
| PRKCA | protein kinase C, alpha | -0.0648958 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0637673 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0631933 |
| LMO7 | LIM domain 7 | -0.0599123 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0597474 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0572314 |
| SMAD3 | SMAD family member 3 | -0.055179 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0551679 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0542983 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0532526 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0525065 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0516024 |
| NABP1 | nucleic acid binding protein 1 | -0.0510523 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.051007 |
| AREG | amphiregulin | -0.0503633 |
| VCL | vinculin | -0.0496146 |
| EGR1 | early growth response 1 | -0.0495665 |
| LAMA4 | laminin, alpha 4 | -0.0487585 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0479003 |
| POF1B | premature ovarian failure, 1B | -0.0477181 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0465837 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0443064 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0433517 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0430999 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0422217 |
| UBAP2 | ubiquitin associated protein 2 | -0.0400126 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0397984 |
| LYZ | lysozyme | -0.0397557 |
| ACTG1 | actin gamma 1 | -0.0395745 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0391496 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0391168 |
| FBXO39 | F-box protein 39 | -0.0382855 |
| PLSCR1 | phospholipid scramblase 1 | -0.0381174 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.036434 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0362414 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0356621 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0355236 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0350351 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0347449 |
| MUC20 | mucin 20, cell surface associated | -0.0341552 |
| TNS4 | tensin 4 | -0.0341423 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0336337 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0336294 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0335853 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.033546 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0325792 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0324954 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0319085 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0315895 |
| CUX1 | cut-like homeobox 1 | -0.0310386 |
| EFNB2 | ephrin-B2 | -0.0305378 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0304709 |
| SDC4 | syndecan 4 | -0.0301061 |
| ARHGAP27 | Rho GTPase activating protein 27 | -0.0292034 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.02893 |
| LCN2 | lipocalin 2 | -0.028204 |
| MSI2 | musashi RNA-binding protein 2 | -0.0277361 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0276934 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0275922 |
| PMP22 | peripheral myelin protein 22 | -0.0272686 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0271032 |
| FHIT | fragile histidine triad | -0.0270767 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0268339 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0267053 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0263204 |
| PKM | pyruvate kinase, muscle | -0.0262712 |
| EPHB2 | EPH receptor B2 | -0.0262437 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0261451 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0260967 |
| MCU | mitochondrial calcium uniporter | -0.025924 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0257799 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0254426 |
| KYNU | kynureninase | -0.0252594 |
| MAP7 | microtubule-associated protein 7 | -0.0250659 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0248619 |
| ATP11A | ATPase, class VI, type 11A | -0.0248205 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0243861 |
