| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0922776 |
| FAM13A | family with sequence similarity 13, member A | 0.0860138 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0844086 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0836818 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0805334 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0666425 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0610738 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0577839 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0575022 |
| MYOF | myoferlin | 0.0557644 |
| HELZ | helicase with zinc finger | 0.0541179 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0508414 |
| RAB1A | RAB1A, member RAS oncogene family | 0.049833 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0475112 |
| MEF2A | myocyte enhancer factor 2A | 0.0467347 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0439711 |
| SRP54 | signal recognition particle 54kDa | 0.0434275 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0430436 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0422602 |
| CALR | calreticulin | 0.0420356 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0410947 |
| PRELID2 | PRELI domain containing 2 | 0.0406873 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0406849 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0403531 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0395792 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0391556 |
| NDRG1 | N-myc downstream regulated 1 | 0.038777 |
| ADM | adrenomedullin | 0.0387617 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0387117 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.038655 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0384464 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0374102 |
| PCBP2 | poly(rC) binding protein 2 | 0.0369234 |
| SETD5 | SET domain containing 5 | 0.0367632 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0366652 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0365409 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0364233 |
| COPA | coatomer protein complex, subunit alpha | 0.036317 |
| RTN4 | reticulon 4 | 0.0361276 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0361032 |
| MSN | moesin | 0.0359853 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0353501 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0353104 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0341733 |
| USP3 | ubiquitin specific peptidase 3 | 0.0334464 |
| SEC24A | SEC24 family member A | 0.033118 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0321404 |
| ATP13A3 | ATPase type 13A3 | 0.0320678 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0320236 |
| HIP1 | huntingtin interacting protein 1 | 0.0318705 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0317042 |
| NBAS | neuroblastoma amplified sequence | 0.0314382 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0314 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0312075 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0310787 |
| RNF220 | ring finger protein 220 | 0.0308941 |
| TFG | TRK-fused gene | 0.0308507 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0304838 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0301683 |
| ZNF292 | zinc finger protein 292 | 0.0300878 |
| INSIG2 | insulin induced gene 2 | 0.0298414 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0296431 |
| FNIP1 | folliculin interacting protein 1 | 0.0288911 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0285274 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0284862 |
| USP37 | ubiquitin specific peptidase 37 | 0.0280153 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0278908 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0276279 |
| CDK19 | cyclin-dependent kinase 19 | 0.0274111 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0273878 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0272138 |
| PCBP3 | poly(rC) binding protein 3 | 0.0271358 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0271304 |
| SCFD1 | sec1 family domain containing 1 | 0.0271285 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0266967 |
| CCNL1 | cyclin L1 | 0.026688 |
| ZNF395 | zinc finger protein 395 | 0.0264965 |
| GOLGB1 | golgin B1 | 0.0263167 |
| CANX | calnexin | 0.0263048 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0262936 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0260986 |
| YEATS2 | YEATS domain containing 2 | 0.0260599 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0259261 |
| NUP58 | nucleoporin 58 | 0.0258529 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0258468 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0258449 |
| CD109 | CD109 molecule | 0.0256555 |
| C1D | C1D nuclear receptor corepressor | 0.0256028 |
| MAGT1 | magnesium transporter 1 | 0.0255994 |
| PKM | pyruvate kinase, muscle | 0.0255318 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0253378 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.0247934 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0246699 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0244705 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0242214 |
| VMP1 | vacuole membrane protein 1 | 0.0242104 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0239936 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0238074 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0237653 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0237471 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.179342 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139274 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.122393 |
| VIM | vimentin | -0.10541 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.103731 |
| MT2A | metallothionein 2A | -0.0985484 |
| TMSB10 | thymosin beta 10 | -0.0980696 |
| KYNU | kynureninase | -0.0951034 |
| CD44 | CD44 molecule (Indian blood group) | -0.0768951 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0743238 |
| FTL | ferritin, light polypeptide | -0.0667605 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0549267 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0527566 |
| NAV3 | neuron navigator 3 | -0.0489586 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.046807 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0466661 |
| NLGN1 | neuroligin 1 | -0.0456892 |
| FN1 | fibronectin 1 | -0.0437954 |
| OSMR | oncostatin M receptor | -0.0405559 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0398922 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0397623 |
| HDAC9 | histone deacetylase 9 | -0.0385697 |
| DST | dystonin | -0.0376767 |
| INHBA | inhibin, beta A | -0.0361835 |
| MAP1B | microtubule-associated protein 1B | -0.0358445 |
| TMSB4X | thymosin beta 4, X-linked | -0.0348672 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0336038 |
| NAV1 | neuron navigator 1 | -0.0330249 |
| TNNC1 | troponin C type 1 (slow) | -0.0328666 |
| RPS19 | ribosomal protein S19 | -0.032138 |
| YBX1 | Y box binding protein 1 | -0.0310927 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0310381 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0307642 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0303048 |
| DTNA | dystrobrevin, alpha | -0.0294225 |
| RPL35A | ribosomal protein L35a | -0.0281835 |
| SEC61G | Sec61 gamma subunit | -0.0281294 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0280733 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0280486 |
| TENM3 | teneurin transmembrane protein 3 | -0.0276427 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0275793 |
| TPTE | transmembrane phosphatase with tensin homology | -0.0272083 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0271307 |
| EHBP1 | EH domain binding protein 1 | -0.0268969 |
| CALD1 | caldesmon 1 | -0.0268084 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | -0.02671 |
| TNS3 | tensin 3 | -0.0264639 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0263902 |
| AK1 | adenylate kinase 1 | -0.0263849 |
| ACTN4 | actinin, alpha 4 | -0.0263245 |
| MT1X | metallothionein 1X | -0.0261039 |
| FSTL1 | follistatin-like 1 | -0.0258609 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0258497 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0254552 |
| CDK6 | cyclin-dependent kinase 6 | -0.0251389 |
| VEGFC | vascular endothelial growth factor C | -0.0251373 |
| RPL32 | ribosomal protein L32 | -0.0250275 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0250195 |
| RPS4X | ribosomal protein S4, X-linked | -0.0249007 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0247067 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0243786 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0240407 |
| EGR1 | early growth response 1 | -0.023801 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0236435 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0234269 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0231581 |
| PAPPA2 | pappalysin 2 | -0.0230676 |
| MYLK | myosin light chain kinase | -0.0230203 |
| ATXN10 | ataxin 10 | -0.0230008 |
| AOPEP | aminopeptidase O (putative) | -0.0229437 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0224626 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.022135 |
| CLMP | CXADR-like membrane protein | -0.0219959 |
| ETV6 | ets variant 6 | -0.0219379 |
| PHF14 | PHD finger protein 14 | -0.0217319 |
| ASPH | aspartate beta-hydroxylase | -0.0215077 |
| RPL36 | ribosomal protein L36 | -0.0213401 |
| RPL34 | ribosomal protein L34 | -0.0212185 |
| CCND1 | cyclin D1 | -0.021184 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0211267 |
| TXNRD1 | thioredoxin reductase 1 | -0.0211027 |
| SBF2 | SET binding factor 2 | -0.0210935 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.02083 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0204858 |
| RACK1 | receptor for activated C kinase 1 | -0.0204319 |
| LAMB1 | laminin, beta 1 | -0.0203044 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.020197 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0201953 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0200615 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0198558 |
| ENO1 | enolase 1, (alpha) | -0.0197373 |
| RPL12 | ribosomal protein L12 | -0.0195673 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0194677 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0191759 |
| MYO9A | myosin IXA | -0.0191322 |
| TUBB | tubulin, beta class I | -0.0190457 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.019032 |
| GLIS3 | GLIS family zinc finger 3 | -0.0189981 |
| RPLP1 | ribosomal protein, large, P1 | -0.0186787 |
| ASTN2 | astrotactin 2 | -0.0186711 |