| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Entecavir (monohydrate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.131061 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.118503 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.112705 |
| FTL | ferritin, light polypeptide | 0.0979112 |
| GOLGA4 | golgin A4 | 0.0965286 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0951887 |
| LDHA | lactate dehydrogenase A | 0.0931661 |
| RPL35A | ribosomal protein L35a | 0.0883591 |
| TMSB10 | thymosin beta 10 | 0.0874078 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0861114 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0859591 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0726017 |
| RPL23 | ribosomal protein L23 | 0.0723055 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0706037 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0674871 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0669713 |
| SRP54 | signal recognition particle 54kDa | 0.0666415 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0633185 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0610838 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0604493 |
| PCBP2 | poly(rC) binding protein 2 | 0.0590393 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0577872 |
| ZNF292 | zinc finger protein 292 | 0.0541508 |
| RPS8 | ribosomal protein S8 | 0.0531479 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0516082 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0507367 |
| RPS6 | ribosomal protein S6 | 0.049946 |
| GOLGA2 | golgin A2 | 0.0489167 |
| UBC | ubiquitin C | 0.0486982 |
| RPS24 | ribosomal protein S24 | 0.0477704 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0458532 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0456702 |
| NUP58 | nucleoporin 58 | 0.0454266 |
| RBM25 | RNA binding motif protein 25 | 0.0451497 |
| RPLP0 | ribosomal protein, large, P0 | 0.0451361 |
| SUCO | SUN domain containing ossification factor | 0.0447088 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0443689 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0415664 |
| WDR45B | WD repeat domain 45B | 0.0412751 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0409832 |
| NOP58 | NOP58 ribonucleoprotein | 0.0406406 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0401933 |
| INSIG2 | insulin induced gene 2 | 0.0393391 |
| KRT8 | keratin 8, type II | 0.0386682 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0385539 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0382721 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0381503 |
| LDHB | lactate dehydrogenase B | 0.0379524 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0379323 |
| RHOA | ras homolog family member A | 0.0374963 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0372529 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0368354 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0368218 |
| RPL8 | ribosomal protein L8 | 0.0366573 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0363918 |
| TUBB | tubulin, beta class I | 0.0361271 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0360035 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0357913 |
| ATF4 | activating transcription factor 4 | 0.0356212 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0352095 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0348064 |
| FOXO3 | forkhead box O3 | 0.0344925 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0344416 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0343952 |
| MATR3 | matrin 3 | 0.0336782 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0336593 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0334799 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0328187 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.03263 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0323611 |
| RPL11 | ribosomal protein L11 | 0.0315614 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0314184 |
| SETD5 | SET domain containing 5 | 0.0310385 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.030915 |
| RPL30 | ribosomal protein L30 | 0.0308907 |
| GNAS | GNAS complex locus | 0.0303171 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0302945 |
| COG5 | component of oligomeric golgi complex 5 | 0.0302321 |
| YBX1 | Y box binding protein 1 | 0.0300935 |
| RACK1 | receptor for activated C kinase 1 | 0.0299725 |
| ARF1 | ADP-ribosylation factor 1 | 0.029633 |
| TMF1 | TATA element modulatory factor 1 | 0.0295806 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0291494 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0291409 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0290192 |
| TXNRD1 | thioredoxin reductase 1 | 0.0288012 |
| RPS4X | ribosomal protein S4, X-linked | 0.0287421 |
| FAM117B | family with sequence similarity 117, member B | 0.0284089 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.027853 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0277857 |
| SEPTIN2 | septin 2 | 0.0276938 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0276421 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.027571 |
| HLA-A | major histocompatibility complex, class I, A | 0.0275483 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.027514 |
| CBX3 | chromobox homolog 3 | 0.0274503 |
| NDRG1 | N-myc downstream regulated 1 | 0.0274481 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0273794 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0273628 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0271239 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DSCAM | Down syndrome cell adhesion molecule | -0.10552 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0788449 |
| VCL | vinculin | -0.074825 |
| RPS2 | ribosomal protein S2 | -0.0678 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0673256 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0672126 |
| TPM4 | tropomyosin 4 | -0.0669614 |
| MCL1 | myeloid cell leukemia 1 | -0.0665676 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0643528 |
| DSPP | dentin sialophosphoprotein | -0.0547197 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0544403 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0540127 |
| CLTC | clathrin, heavy chain (Hc) | -0.050689 |
| MKI67 | marker of proliferation Ki-67 | -0.0504668 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0495148 |
| NEBL | nebulette | -0.0471499 |
| PRELID2 | PRELI domain containing 2 | -0.045615 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0449406 |
| CENPF | centromere protein F, 350/400kDa | -0.0445434 |
| WWC2 | WW and C2 domain containing 2 | -0.0443811 |
| ASPH | aspartate beta-hydroxylase | -0.0442897 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.042519 |
| SMYD3 | SET and MYND domain containing 3 | -0.0405786 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0393099 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0374951 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0367783 |
| EZR | ezrin | -0.0362931 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0358163 |
| LDLR | low density lipoprotein receptor | -0.0338193 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0334675 |
| UTRN | utrophin | -0.0326453 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0325265 |
| TJP1 | tight junction protein 1 | -0.0323446 |
| VMP1 | vacuole membrane protein 1 | -0.0315374 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0311301 |
| AHNAK | AHNAK nucleoprotein | -0.0309796 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0309767 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0301876 |
| GPHN | gephyrin | -0.0300523 |
| DSG2 | desmoglein 2 | -0.0299623 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0296579 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.029445 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0289882 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0289424 |
| RPS18 | ribosomal protein S18 | -0.02853 |
| APP | amyloid beta (A4) precursor protein | -0.0280184 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0274776 |
| NCKAP1 | NCK-associated protein 1 | -0.0269257 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0256667 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0256021 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0250978 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0250423 |
| SNX14 | sorting nexin 14 | -0.0249535 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0248462 |
| ANXA2 | annexin A2 | -0.0246446 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0242184 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0241517 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0241225 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0240099 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0239433 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0238312 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0237518 |
| MAP4 | microtubule-associated protein 4 | -0.023681 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0235334 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0235185 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.0233476 |
| AXIN2 | axin 2 | -0.0232243 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0232108 |
| TENM3 | teneurin transmembrane protein 3 | -0.0232067 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0231171 |
| KIAA1328 | KIAA1328 | -0.0229972 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0229824 |
| H1-4 | H1.4 linker histone, cluster member | -0.0229509 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0229384 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.0229309 |
| DUSP5 | dual specificity phosphatase 5 | -0.0228012 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0226534 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0226333 |
| DIAPH2 | diaphanous-related formin 2 | -0.0224852 |
| DNMBP | dynamin binding protein | -0.022421 |
| GOLGB1 | golgin B1 | -0.0223853 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0222316 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0219851 |
| SETX | senataxin | -0.0218206 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.021759 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0217429 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0217106 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0216844 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0216786 |
| MYO9A | myosin IXA | -0.0215817 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0215254 |
| HOXB3 | homeobox B3 | -0.0215216 |
| JAK1 | Janus kinase 1 | -0.0214058 |
| PLEC | plectin | -0.0213591 |
| WWOX | WW domain containing oxidoreductase | -0.0212081 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0211879 |
| RSPH3 | radial spoke 3 homolog (Chlamydomonas) | -0.0210605 |
| FHIT | fragile histidine triad | -0.0209913 |
| CHRM3 | cholinergic receptor, muscarinic 3 | -0.0208743 |
| NRDC | nardilysin convertase | -0.0206639 |
