| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.173331 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.154126 |
| FN1 | fibronectin 1 | 0.137337 |
| FAM13A | family with sequence similarity 13, member A | 0.120144 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0955811 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0800219 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0713047 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0673881 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0629599 |
| CDCP1 | CUB domain containing protein 1 | 0.0575244 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.057198 |
| NGLY1 | N-glycanase 1 | 0.0556661 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0537312 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.047625 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0469258 |
| ZNF292 | zinc finger protein 292 | 0.045238 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0449665 |
| USP3 | ubiquitin specific peptidase 3 | 0.0428818 |
| LOX | lysyl oxidase | 0.0428296 |
| PDE10A | phosphodiesterase 10A | 0.0415983 |
| ATP13A3 | ATPase type 13A3 | 0.0410686 |
| NDRG1 | N-myc downstream regulated 1 | 0.0409155 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0405299 |
| SPAG9 | sperm associated antigen 9 | 0.0403449 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0391708 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0373652 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0366152 |
| RNF24 | ring finger protein 24 | 0.0358277 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0356955 |
| CD109 | CD109 molecule | 0.0355848 |
| FLNB | filamin B, beta | 0.0353512 |
| RTN4 | reticulon 4 | 0.0348848 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0336908 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0335343 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0332326 |
| SETD5 | SET domain containing 5 | 0.0329235 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0318502 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0314464 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0314036 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0312515 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0312016 |
| HELZ | helicase with zinc finger | 0.0311666 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.031047 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0309107 |
| GOLGA4 | golgin A4 | 0.0308023 |
| ARRDC3 | arrestin domain containing 3 | 0.0300741 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0294845 |
| MEF2A | myocyte enhancer factor 2A | 0.0286905 |
| RUNX1 | runt-related transcription factor 1 | 0.0283985 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0278038 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0275886 |
| ZNF148 | zinc finger protein 148 | 0.0273137 |
| NUP58 | nucleoporin 58 | 0.0271045 |
| AXL | AXL receptor tyrosine kinase | 0.0268816 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.026449 |
| SYAP1 | synapse associated protein 1 | 0.0261181 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0258707 |
| SEC24A | SEC24 family member A | 0.0257426 |
| INSIG2 | insulin induced gene 2 | 0.0256092 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.025552 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0252586 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0252562 |
| STC1 | stanniocalcin 1 | 0.0239173 |
| LDHA | lactate dehydrogenase A | 0.0237862 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0229764 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0229617 |
| ANXA5 | annexin A5 | 0.0226594 |
| RLF | rearranged L-myc fusion | 0.0224917 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0223279 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0221051 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0219059 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0215714 |
| OGA | O-GlcNAcase | 0.0214671 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0213748 |
| ADM | adrenomedullin | 0.0213236 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0211642 |
| SNX9 | sorting nexin 9 | 0.0211194 |
| CCNL1 | cyclin L1 | 0.0210705 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.020755 |
| RNF149 | ring finger protein 149 | 0.0202415 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0200839 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0198272 |
| SMAD3 | SMAD family member 3 | 0.0197997 |
| FOXJ3 | forkhead box J3 | 0.0197859 |
| RNF145 | ring finger protein 145 | 0.0197098 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0196946 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0196834 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0191716 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0190556 |
| DUSP6 | dual specificity phosphatase 6 | 0.0187773 |
| WDR45B | WD repeat domain 45B | 0.0187246 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0186509 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0184993 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0184862 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0182989 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0182623 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0182499 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0181245 |
| TET3 | tet methylcytosine dioxygenase 3 | 0.0181186 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0181147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.163607 |
| VIM | vimentin | -0.152378 |
| HMGA2 | high mobility group AT-hook 2 | -0.149836 |
| COL5A1 | collagen, type V, alpha 1 | -0.136735 |
| TMSB10 | thymosin beta 10 | -0.110761 |
| CDH13 | cadherin 13 | -0.105414 |
| NAV1 | neuron navigator 1 | -0.100922 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0996231 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0813047 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0798486 |
| ACTG1 | actin gamma 1 | -0.0711389 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0667178 |
| GLIS3 | GLIS family zinc finger 3 | -0.0630273 |
| AHNAK | AHNAK nucleoprotein | -0.0592011 |
| MYO10 | myosin X | -0.0578383 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0572755 |
| VCL | vinculin | -0.0570859 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0537406 |
| DST | dystonin | -0.0521097 |
| CD44 | CD44 molecule (Indian blood group) | -0.0500522 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0487888 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0446294 |
| MT2A | metallothionein 2A | -0.0440454 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0423667 |
| ASPH | aspartate beta-hydroxylase | -0.0423447 |
| INTS6 | integrator complex subunit 6 | -0.0403113 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0391067 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0389211 |
| PLEC | plectin | -0.0385908 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0382741 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0378913 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0377231 |
| FMN1 | formin 1 | -0.0372069 |
| RAI14 | retinoic acid induced 14 | -0.0370355 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0367704 |
| EGFR | epidermal growth factor receptor | -0.0360647 |
| PRKCA | protein kinase C, alpha | -0.0357401 |
| FRMD4A | FERM domain containing 4A | -0.0356073 |
| KIAA1549L | KIAA1549-like | -0.0353699 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0343757 |
| RAD51B | RAD51 paralog B | -0.0339771 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0339719 |
| NABP1 | nucleic acid binding protein 1 | -0.033701 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0334243 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0330369 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0327017 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0323003 |
| ATXN1 | ataxin 1 | -0.0317809 |
| PRSS23 | protease, serine, 23 | -0.0314379 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0310301 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0310182 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0308432 |
| WWOX | WW domain containing oxidoreductase | -0.0306904 |
| DIAPH2 | diaphanous-related formin 2 | -0.0303814 |
| TPM1 | tropomyosin 1 (alpha) | -0.0302366 |
| SMYD3 | SET and MYND domain containing 3 | -0.029527 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0292656 |
| CLMP | CXADR-like membrane protein | -0.0290879 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0285469 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0284313 |
| ATG7 | autophagy related 7 | -0.028145 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0281287 |
| IGF2 | insulin-like growth factor 2 | -0.0280896 |
| RPLP1 | ribosomal protein, large, P1 | -0.0280692 |
| RPS6 | ribosomal protein S6 | -0.0278944 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0277194 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.027361 |
| NAV3 | neuron navigator 3 | -0.0273551 |
| CCDC91 | coiled-coil domain containing 91 | -0.0272427 |
| COL1A1 | collagen, type I, alpha 1 | -0.0269371 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0264947 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0263541 |
| AEBP2 | AE binding protein 2 | -0.0263471 |
| CDK6 | cyclin-dependent kinase 6 | -0.02634 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.026203 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0259853 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0257413 |
| TGFB1 | transforming growth factor, beta 1 | -0.0255526 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0255392 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.025534 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0251817 |
| FLNA | filamin A, alpha | -0.0250876 |
| CUX1 | cut-like homeobox 1 | -0.0248779 |
| CDK14 | cyclin-dependent kinase 14 | -0.0247108 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0246751 |
| RPS19 | ribosomal protein S19 | -0.0246546 |
| ENO1 | enolase 1, (alpha) | -0.0242942 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0241626 |
| AFF3 | AF4/FMR2 family, member 3 | -0.024062 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.022765 |
| RPS8 | ribosomal protein S8 | -0.0227405 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0223004 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0222274 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0220506 |
| RRBP1 | ribosome binding protein 1 | -0.0219337 |
| LMNA | lamin A/C | -0.0218264 |
| CEP112 | centrosomal protein 112kDa | -0.0215477 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0213464 |
| LRRC23 | leucine rich repeat containing 23 | -0.0211886 |
| FER | fer (fps/fes related) tyrosine kinase | -0.021171 |
