| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.172322 |
| TXNRD1 | thioredoxin reductase 1 | 0.141538 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.125173 |
| VIM | vimentin | 0.0951553 |
| EZR | ezrin | 0.0823046 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0816822 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0761418 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0748375 |
| RTN4 | reticulon 4 | 0.0743038 |
| EREG | epiregulin | 0.0706603 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0706086 |
| RAI1 | retinoic acid induced 1 | 0.0701094 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0665493 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0594679 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0594055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0582285 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0581324 |
| JMJD1C | jumonji domain containing 1C | 0.0578813 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.057197 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0569414 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0561974 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0558103 |
| TMEM41B | transmembrane protein 41B | 0.055576 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0554011 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0553988 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.055382 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0550514 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0541266 |
| SPAG9 | sperm associated antigen 9 | 0.0531738 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0523769 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0517744 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0508124 |
| TOP1 | topoisomerase (DNA) I | 0.0504182 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0491879 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0489851 |
| APP | amyloid beta (A4) precursor protein | 0.0476253 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0476251 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0476079 |
| MATR3 | matrin 3 | 0.0465312 |
| AHNAK | AHNAK nucleoprotein | 0.0465074 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0453529 |
| CCNL1 | cyclin L1 | 0.0452275 |
| ERBIN | erbb2 interacting protein | 0.0446962 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0438537 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0437936 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0436736 |
| POTEF | POTE ankyrin domain family, member F | 0.0418521 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0412824 |
| ANXA1 | annexin A1 | 0.0406986 |
| NUP58 | nucleoporin 58 | 0.0406947 |
| XPO1 | exportin 1 | 0.0404229 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0403042 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0397361 |
| ZNF292 | zinc finger protein 292 | 0.0396887 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0393553 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0393299 |
| LDHA | lactate dehydrogenase A | 0.0389684 |
| CEP170 | centrosomal protein 170kDa | 0.0388659 |
| SRPK2 | SRSF protein kinase 2 | 0.0387911 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0387593 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0384944 |
| RBM39 | RNA binding motif protein 39 | 0.0381285 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0380395 |
| WDR43 | WD repeat domain 43 | 0.0379911 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.037682 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0369248 |
| SRGN | serglycin | 0.0367316 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0364819 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0363708 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0361247 |
| PCBP2 | poly(rC) binding protein 2 | 0.0355915 |
| SETD5 | SET domain containing 5 | 0.035437 |
| WAC | WW domain containing adaptor with coiled-coil | 0.035349 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0353472 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0352192 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0349891 |
| OGA | O-GlcNAcase | 0.0345845 |
| GOLGA4 | golgin A4 | 0.0344845 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0343662 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0342221 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.034218 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0340822 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.034062 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0340215 |
| WDR26 | WD repeat domain 26 | 0.0337973 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0336546 |
| CENPF | centromere protein F, 350/400kDa | 0.0332745 |
| TNPO1 | transportin 1 | 0.0332389 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0331535 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.032969 |
| PUM1 | pumilio RNA-binding family member 1 | 0.032966 |
| ETNK1 | ethanolamine kinase 1 | 0.0328656 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0328454 |
| ZFR | zinc finger RNA binding protein | 0.0327938 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0327797 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0324676 |
| ATP13A3 | ATPase type 13A3 | 0.0321954 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0321746 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0316483 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0315424 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.177845 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0903664 |
| CD44 | CD44 molecule (Indian blood group) | -0.0892095 |
| CADM2 | cell adhesion molecule 2 | -0.087068 |
| DST | dystonin | -0.083093 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0750702 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0707906 |
| TNS3 | tensin 3 | -0.0706479 |
| PRELID2 | PRELI domain containing 2 | -0.0619386 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0573823 |
| RAD51B | RAD51 paralog B | -0.0503341 |
| RNF213 | ring finger protein 213 | -0.049713 |
| EFNA5 | ephrin-A5 | -0.0492497 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0455652 |
| NEK10 | NIMA-related kinase 10 | -0.0453267 |
| TMSB10 | thymosin beta 10 | -0.0433924 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0430557 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.042677 |
| HLA-B | major histocompatibility complex, class I, B | -0.0418147 |
| PDE10A | phosphodiesterase 10A | -0.0412194 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0399514 |
| INTS6 | integrator complex subunit 6 | -0.0397246 |
| EPHA4 | EPH receptor A4 | -0.0373978 |
| DPH6 | diphthamine biosynthesis 6 | -0.0369391 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0360453 |
| SP100 | SP100 nuclear antigen | -0.0359978 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0331785 |
| DNER | delta/notch-like EGF repeat containing | -0.0321924 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0308973 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0306839 |
| RIGI | RNA sensor RIG-I | -0.029871 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.029131 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0274125 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0266936 |
| AEBP2 | AE binding protein 2 | -0.0263144 |
| TGM2 | transglutaminase 2 | -0.0259578 |
| ECE1 | endothelin converting enzyme 1 | -0.0251305 |
| HDAC9 | histone deacetylase 9 | -0.0250111 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0245082 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0241543 |
| EGFR | epidermal growth factor receptor | -0.0241082 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0238865 |
| PLSCR1 | phospholipid scramblase 1 | -0.0234672 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0226985 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0219712 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0217597 |
| SUMF1 | sulfatase modifying factor 1 | -0.021641 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0214527 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.021387 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0212236 |
| WDR27 | WD repeat domain 27 | -0.0212132 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0200191 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0197281 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0195652 |
| CMIP | c-Maf inducing protein | -0.0193914 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0189897 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0188614 |
| EXOC4 | exocyst complex component 4 | -0.0187635 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0185968 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0181004 |
| MT2A | metallothionein 2A | -0.0178241 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0176414 |
| PRKCE | protein kinase C, epsilon | -0.0175638 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0175598 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0173875 |
| MYOF | myoferlin | -0.0171657 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | -0.0169909 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0169366 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0168801 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0160618 |
| RPL38 | ribosomal protein L38 | -0.0160397 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.0159205 |
| LMNTD1 | lamin tail domain containing 1 | -0.0159132 |
| SDC4 | syndecan 4 | -0.015802 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0157237 |
| DENND1A | DENN/MADD domain containing 1A | -0.0155272 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0154522 |
| FHIT | fragile histidine triad | -0.0153715 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0153484 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0153163 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.015021 |
| VCL | vinculin | -0.014975 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0149288 |
| WFDC10B | WAP four-disulfide core domain 10B | -0.0148247 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0146518 |
| NEBL | nebulette | -0.0145012 |
| RPL31 | ribosomal protein L31 | -0.0145004 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0144025 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0143599 |
| TPRG1 | tumor protein p63 regulated 1 | -0.0143064 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0142264 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0141079 |
| CCDC57 | coiled-coil domain containing 57 | -0.0140971 |
| SMAD9 | SMAD family member 9 | -0.0140893 |
| LRRC49 | leucine rich repeat containing 49 | -0.0140852 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0140583 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0140208 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0138135 |
| PYGL | phosphorylase, glycogen, liver | -0.0136011 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0135555 |
