| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.156878 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.144834 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.122594 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.103991 |
| SMAD3 | SMAD family member 3 | 0.100027 |
| FAM13A | family with sequence similarity 13, member A | 0.0899494 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.088267 |
| PCBP2 | poly(rC) binding protein 2 | 0.0882347 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0881991 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0866551 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0854104 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0820692 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0730762 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0722912 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0690366 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0648748 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.062944 |
| RUNX1 | runt-related transcription factor 1 | 0.0614011 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0601688 |
| EFNA5 | ephrin-A5 | 0.0598624 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0588374 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0569506 |
| HELZ | helicase with zinc finger | 0.0561688 |
| FLNB | filamin B, beta | 0.0553988 |
| SIK3 | SIK family kinase 3 | 0.0541392 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0527727 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0525922 |
| NAV2 | neuron navigator 2 | 0.0523463 |
| ASPH | aspartate beta-hydroxylase | 0.0511148 |
| NDRG1 | N-myc downstream regulated 1 | 0.050094 |
| RBM39 | RNA binding motif protein 39 | 0.0493697 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0463895 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0462372 |
| HAS2 | hyaluronan synthase 2 | 0.0438643 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0433924 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0426697 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.041774 |
| PRELID2 | PRELI domain containing 2 | 0.0417234 |
| PTK2 | protein tyrosine kinase 2 | 0.0413988 |
| KLF6 | Kruppel-like factor 6 | 0.0413275 |
| ANXA1 | annexin A1 | 0.0409984 |
| ATP13A3 | ATPase type 13A3 | 0.0409471 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0404618 |
| EZR | ezrin | 0.0400292 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.039477 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0392961 |
| SPAG9 | sperm associated antigen 9 | 0.0392849 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0382941 |
| CCNL1 | cyclin L1 | 0.0381556 |
| TGM2 | transglutaminase 2 | 0.0379493 |
| RARB | retinoic acid receptor, beta | 0.0379362 |
| ADD3 | adducin 3 (gamma) | 0.0375194 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0368139 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0354859 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0349655 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0347478 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0345121 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0338781 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0338452 |
| USP34 | ubiquitin specific peptidase 34 | 0.0335497 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0335038 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0317697 |
| FBXO32 | F-box protein 32 | 0.0313647 |
| ARRDC3 | arrestin domain containing 3 | 0.0306462 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0306456 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0305195 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.030449 |
| PFKP | phosphofructokinase, platelet | 0.0304361 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0300608 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.030015 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0298777 |
| ECE1 | endothelin converting enzyme 1 | 0.0297365 |
| PHIP | pleckstrin homology domain interacting protein | 0.0297072 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0294865 |
| IL6ST | interleukin 6 signal transducer | 0.0293626 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0291823 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0290669 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0288788 |
| PARD3 | par-3 family cell polarity regulator | 0.0287319 |
| CD44 | CD44 molecule (Indian blood group) | 0.0285128 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0284869 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0283057 |
| ATXN1 | ataxin 1 | 0.0282009 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0280715 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0278049 |
| AHR | aryl hydrocarbon receptor | 0.0277529 |
| SLTM | SAFB-like, transcription modulator | 0.0277337 |
| ANXA2 | annexin A2 | 0.0276651 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0276558 |
| CDCP1 | CUB domain containing protein 1 | 0.0275868 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0274476 |
| MT2A | metallothionein 2A | 0.0273485 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0273148 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0270328 |
| YBX3 | Y box binding protein 3 | 0.0270287 |
| MSN | moesin | 0.0269323 |
| RTN4 | reticulon 4 | 0.0266145 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0263639 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0262876 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0261063 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.136348 |
| TMSB10 | thymosin beta 10 | -0.124216 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0955518 |
| HMGA2 | high mobility group AT-hook 2 | -0.0840764 |
| GLCCI1 | glucocorticoid induced 1 | -0.0758745 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0658116 |
| CDH13 | cadherin 13 | -0.0639446 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0620893 |
| FAM20C | family with sequence similarity 20, member C | -0.0602587 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0575116 |
| LOX | lysyl oxidase | -0.0487937 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0487433 |
| NTN4 | netrin 4 | -0.0479553 |
| ZNF804A | zinc finger protein 804A | -0.043185 |
| VIM | vimentin | -0.042899 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0428601 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0427228 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0419238 |
| DST | dystonin | -0.041481 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.040886 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0393871 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0385735 |
| NRG1 | neuregulin 1 | -0.0377284 |
| HDLBP | high density lipoprotein binding protein | -0.0362183 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0360692 |
| VRK2 | vaccinia related kinase 2 | -0.0356581 |
| EHBP1 | EH domain binding protein 1 | -0.0350978 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0350396 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.034983 |
| S100A6 | S100 calcium binding protein A6 | -0.0333707 |
| AADAC | arylacetamide deacetylase | -0.0329458 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0308695 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0306412 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0303975 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0303708 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0302805 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.030104 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0300894 |
| OSMR | oncostatin M receptor | -0.0298604 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0293851 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0289337 |
| KYNU | kynureninase | -0.0289334 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0285079 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0281413 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0276853 |
| DNER | delta/notch-like EGF repeat containing | -0.0275917 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0274821 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0268386 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0261236 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0253261 |
| ATM | ATM serine/threonine kinase | -0.025291 |
| RAI14 | retinoic acid induced 14 | -0.0251077 |
| GOLGA3 | golgin A3 | -0.0248876 |
| FBN1 | fibrillin 1 | -0.024722 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0246996 |
| ATG7 | autophagy related 7 | -0.0244989 |
| NAV3 | neuron navigator 3 | -0.0242806 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0241894 |
| EXOC4 | exocyst complex component 4 | -0.0238818 |
| GOLGB1 | golgin B1 | -0.0233369 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0232269 |
| ENOSF1 | enolase superfamily member 1 | -0.0232041 |
| CDK13 | cyclin-dependent kinase 13 | -0.0230285 |
| ANTXR1 | anthrax toxin receptor 1 | -0.022789 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0224957 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0224138 |
| CLMP | CXADR-like membrane protein | -0.0223826 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0222652 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0219075 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0218456 |
| MECOM | MDS1 and EVI1 complex locus | -0.0218436 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0217985 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0217846 |
| RASAL2 | RAS protein activator like 2 | -0.0217413 |
| RSU1 | Ras suppressor protein 1 | -0.0215616 |
| PCNX4 | pecanex 4 | -0.0214401 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0210094 |
| CUX1 | cut-like homeobox 1 | -0.0210087 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0209889 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0209888 |
| PRSS23 | protease, serine, 23 | -0.0206778 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0202708 |
| ZNF407 | zinc finger protein 407 | -0.0202457 |
| R3HDM2 | R3H domain containing 2 | -0.0202402 |
| SYT1 | synaptotagmin I | -0.0202016 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0201762 |
| PRRX1 | paired related homeobox 1 | -0.020096 |
| GLIS3 | GLIS family zinc finger 3 | -0.0197356 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0197174 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0195813 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0195364 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0194166 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0192999 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0190728 |
| RPL35A | ribosomal protein L35a | -0.0189128 |
| TMSB4X | thymosin beta 4, X-linked | -0.0187315 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0186495 |
| HM13 | histocompatibility (minor) 13 | -0.0186149 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0185414 |
| OXSR1 | oxidative stress responsive 1 | -0.018431 |
