| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.0783015 |
| TXNRD1 | thioredoxin reductase 1 | 0.0676353 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0600756 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0524475 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0493565 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0484561 |
| WDR43 | WD repeat domain 43 | 0.0353243 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0269477 |
| NNMT | nicotinamide N-methyltransferase | 0.0256115 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0246963 |
| OSMR | oncostatin M receptor | 0.0238378 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0221669 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0214528 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0204404 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0203384 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0196339 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0195811 |
| IL6 | interleukin 6 | 0.0195226 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0186078 |
| NTN4 | netrin 4 | 0.0184158 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0178076 |
| FGA | fibrinogen alpha chain | 0.0173017 |
| MKI67 | marker of proliferation Ki-67 | 0.0171429 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0168439 |
| TMEM87A | transmembrane protein 87A | 0.0165293 |
| SP3 | Sp3 transcription factor | 0.0156147 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0155774 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0154921 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.015358 |
| SRGN | serglycin | 0.0152231 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0149441 |
| UBXN4 | UBX domain protein 4 | 0.0148535 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0145861 |
| MFF | mitochondrial fission factor | 0.0145595 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | 0.0144325 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0142208 |
| FLOT1 | flotillin 1 | 0.0140307 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0138633 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0138122 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0136674 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0135472 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.013529 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0134513 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0134363 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0132835 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0130883 |
| ATXN3 | ataxin 3 | 0.0127542 |
| INHBA | inhibin, beta A | 0.0127032 |
| ANXA5 | annexin A5 | 0.0125694 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0125105 |
| HLA-B | major histocompatibility complex, class I, B | 0.012502 |
| LDHA | lactate dehydrogenase A | 0.0123529 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.012296 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.0122761 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0122405 |
| RAN | RAN, member RAS oncogene family | 0.0121637 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.0121304 |
| ITGB5 | integrin, beta 5 | 0.0120881 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.012047 |
| NLN | neurolysin (metallopeptidase M3 family) | 0.0119888 |
| CDCP1 | CUB domain containing protein 1 | 0.0119584 |
| LAMB1 | laminin, beta 1 | 0.0119001 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0118944 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0117333 |
| PTEN | phosphatase and tensin homolog | 0.0116353 |
| ARTN | artemin | 0.0116344 |
| HM13 | histocompatibility (minor) 13 | 0.0116338 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0115323 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0113299 |
| VEGFC | vascular endothelial growth factor C | 0.0112804 |
| MYADM | myeloid-associated differentiation marker | 0.0112549 |
| MT1F | metallothionein 1F | 0.0111812 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0111663 |
| FAM168A | family with sequence similarity 168, member A | 0.0111391 |
| DSTN | destrin (actin depolymerizing factor) | 0.0111127 |
| TMEM167A | transmembrane protein 167A | 0.0110253 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0109658 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0109401 |
| IMMT | inner membrane protein, mitochondrial | 0.0109317 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0109244 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.0108312 |
| AXL | AXL receptor tyrosine kinase | 0.0107977 |
| HDAC9 | histone deacetylase 9 | 0.0107481 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0107238 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 0.010642 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0106091 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0105914 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0105459 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0104813 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0102608 |
| CCNT1 | cyclin T1 | 0.0102588 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0102432 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0102328 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0101545 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0101271 |
| KIFC3 | kinesin family member C3 | 0.00996973 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.00995002 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.00988048 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.00986828 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.00986825 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.215984 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.212218 |
| FTL | ferritin, light polypeptide | -0.204459 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.159273 |
| TMSB10 | thymosin beta 10 | -0.149415 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145121 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.118371 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.117147 |
| FMNL2 | formin-like 2 | -0.115741 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.10705 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0926805 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0875644 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0866382 |
| DST | dystonin | -0.0849528 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0836621 |
| FNDC3B | fibronectin type III domain containing 3B | -0.079088 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0765652 |
| ACTG1 | actin gamma 1 | -0.0745451 |
| AHNAK | AHNAK nucleoprotein | -0.0719729 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0694182 |
| IER3 | immediate early response 3 | -0.0676939 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0674784 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0653003 |
| CMIP | c-Maf inducing protein | -0.0630071 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0625574 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0609449 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0600241 |
| EXT1 | exostosin glycosyltransferase 1 | -0.058361 |
| RPLP1 | ribosomal protein, large, P1 | -0.056166 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0561271 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0555085 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0553257 |
| FLNB | filamin B, beta | -0.0547667 |
| PARD3 | par-3 family cell polarity regulator | -0.0543067 |
| ASPH | aspartate beta-hydroxylase | -0.0537297 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0533736 |
| FBXO11 | F-box protein 11 | -0.0524951 |
| APP | amyloid beta (A4) precursor protein | -0.0515691 |
| PKM | pyruvate kinase, muscle | -0.0515242 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0510414 |
| MCL1 | myeloid cell leukemia 1 | -0.0504623 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0504594 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0491343 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0481032 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0480629 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0478542 |
| GNAS | GNAS complex locus | -0.0478082 |
| VIM | vimentin | -0.0470673 |
| RPL19 | ribosomal protein L19 | -0.046947 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0466785 |
| YBX1 | Y box binding protein 1 | -0.0453277 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0453207 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.044773 |
| RAB1A | RAB1A, member RAS oncogene family | -0.044197 |
| PDE8A | phosphodiesterase 8A | -0.0434877 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0431458 |
| MYOF | myoferlin | -0.0425602 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0417416 |
| CANX | calnexin | -0.0413748 |
| RAD51B | RAD51 paralog B | -0.0412418 |
| PFN1 | profilin 1 | -0.0406973 |
| CYTH1 | cytohesin 1 | -0.0405276 |
| UTRN | utrophin | -0.0404376 |
| ANXA2 | annexin A2 | -0.0400023 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.039965 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0394367 |
| EFNA5 | ephrin-A5 | -0.0387923 |
| FLNA | filamin A, alpha | -0.0380465 |
| PTK2 | protein tyrosine kinase 2 | -0.0379961 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0371451 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0370041 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0364387 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0360724 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0356914 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0355909 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0355103 |
| RPS19 | ribosomal protein S19 | -0.0354602 |
| FNBP1L | formin binding protein 1-like | -0.0353984 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0347651 |
| LMNA | lamin A/C | -0.0343301 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0342628 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0339082 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0337415 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0336524 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0336083 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0333539 |
| S100A10 | S100 calcium binding protein A10 | -0.0331949 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0331473 |
| TFRC | transferrin receptor | -0.0328409 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0327911 |
| FUS | FUS RNA binding protein | -0.0326398 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0324899 |
| BICC1 | BicC family RNA binding protein 1 | -0.0321607 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.031797 |
| ZNF207 | zinc finger protein 207 | -0.0317596 |
| CUX1 | cut-like homeobox 1 | -0.0317188 |
| MYO1E | myosin IE | -0.0316598 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0311965 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0310904 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0310846 |
