| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.151918 |
| PGK1 | phosphoglycerate kinase 1 | 0.130559 |
| TMSB10 | thymosin beta 10 | 0.119238 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.117132 |
| SMYD3 | SET and MYND domain containing 3 | 0.116204 |
| FLNB | filamin B, beta | 0.113701 |
| MYOF | myoferlin | 0.102247 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.101586 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0933712 |
| GPC6 | glypican 6 | 0.0923374 |
| ASPH | aspartate beta-hydroxylase | 0.0912153 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0911044 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0838231 |
| AHNAK | AHNAK nucleoprotein | 0.0829499 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0812443 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0805873 |
| NDRG1 | N-myc downstream regulated 1 | 0.0805712 |
| COPA | coatomer protein complex, subunit alpha | 0.0803211 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.079076 |
| CDC73 | cell division cycle 73 | 0.0776459 |
| MEF2A | myocyte enhancer factor 2A | 0.0757474 |
| DENND1A | DENN/MADD domain containing 1A | 0.0708448 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0682805 |
| GOLGA4 | golgin A4 | 0.0680709 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0671074 |
| NF1 | neurofibromin 1 | 0.0655247 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0649445 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0648408 |
| KIF5B | kinesin family member 5B | 0.0635329 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0627311 |
| VCL | vinculin | 0.0598035 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0592712 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0584628 |
| LDHA | lactate dehydrogenase A | 0.0577292 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0576705 |
| RAB1A | RAB1A, member RAS oncogene family | 0.057462 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.054673 |
| MATR3 | matrin 3 | 0.0542894 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0537171 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0520309 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0519194 |
| WAC | WW domain containing adaptor with coiled-coil | 0.051363 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0502643 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.050053 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0487805 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0484935 |
| WDR45B | WD repeat domain 45B | 0.0484199 |
| TFG | TRK-fused gene | 0.0481739 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0479288 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0463172 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0459027 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0448112 |
| RUNX1 | runt-related transcription factor 1 | 0.0447296 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0447183 |
| NEK7 | NIMA-related kinase 7 | 0.0440268 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0423448 |
| SMAD3 | SMAD family member 3 | 0.0413428 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0411224 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0400339 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0400012 |
| CERS6 | ceramide synthase 6 | 0.0398891 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0379007 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0370433 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0367486 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0366579 |
| FTL | ferritin, light polypeptide | 0.0362408 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0360719 |
| COG5 | component of oligomeric golgi complex 5 | 0.0360603 |
| PARD3 | par-3 family cell polarity regulator | 0.0360003 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0355899 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.034749 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0341805 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0338286 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0336348 |
| DST | dystonin | 0.0335737 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0331048 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0317954 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0311065 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0308149 |
| OGA | O-GlcNAcase | 0.0294456 |
| MCL1 | myeloid cell leukemia 1 | 0.0292489 |
| RPL35A | ribosomal protein L35a | 0.0282635 |
| RPL23 | ribosomal protein L23 | 0.0274069 |
| ANXA2 | annexin A2 | 0.0273666 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0273051 |
| CANX | calnexin | 0.0272552 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0264803 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0262708 |
| SETD5 | SET domain containing 5 | 0.0258726 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0254034 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0251067 |
| CREB5 | cAMP responsive element binding protein 5 | 0.023303 |
| TBC1D22A | TBC1 domain family, member 22A | 0.022126 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0208008 |
| POTEF | POTE ankyrin domain family, member F | 0.0206375 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0206324 |
| ENO1 | enolase 1, (alpha) | 0.0203448 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0201897 |
| LSAMP | limbic system-associated membrane protein | 0.0197643 |
| RPLP2 | ribosomal protein, large, P2 | 0.0195944 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMA4 | laminin, alpha 4 | -0.186455 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.156387 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.125305 |
| RPS6 | ribosomal protein S6 | -0.115439 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104545 |
| PDLIM5 | PDZ and LIM domain 5 | -0.103387 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0986368 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0905038 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0889757 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0869838 |
| RPS8 | ribosomal protein S8 | -0.0868599 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0863823 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0846542 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0839786 |
| VIM | vimentin | -0.0818221 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0807301 |
| PTMA | prothymosin, alpha | -0.0802015 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0796933 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0766296 |
| RPS3 | ribosomal protein S3 | -0.0737374 |
| RSF1 | remodeling and spacing factor 1 | -0.0735846 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.073053 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0729222 |
| CTBP2 | C-terminal binding protein 2 | -0.0700536 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0672217 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0663334 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0634807 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0629512 |
| SLTM | SAFB-like, transcription modulator | -0.0624879 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0605936 |
| FNIP1 | folliculin interacting protein 1 | -0.0605349 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0598814 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0597722 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0579325 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0573033 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0561381 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0555096 |
| AOPEP | aminopeptidase O (putative) | -0.0553782 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0538556 |
| PDE10A | phosphodiesterase 10A | -0.0531339 |
| TOP1 | topoisomerase (DNA) I | -0.0528522 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0523596 |
| RPL15 | ribosomal protein L15 | -0.0519021 |
| JMJD1C | jumonji domain containing 1C | -0.0515737 |
| CD2AP | CD2-associated protein | -0.0504884 |
| APP | amyloid beta (A4) precursor protein | -0.049489 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0492347 |
| CALU | calumenin | -0.0490886 |
| RPL19 | ribosomal protein L19 | -0.0483411 |
| RPL8 | ribosomal protein L8 | -0.0459895 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.044969 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0441796 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0437343 |
| RORA | RAR-related orphan receptor A | -0.0434853 |
| RIGI | RNA sensor RIG-I | -0.0427266 |
| ERBIN | erbb2 interacting protein | -0.0420594 |
| VMP1 | vacuole membrane protein 1 | -0.041853 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0417718 |
| TXNRD1 | thioredoxin reductase 1 | -0.0407006 |
| RPL11 | ribosomal protein L11 | -0.0394929 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0384376 |
| SBF2 | SET binding factor 2 | -0.0382377 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0378677 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0373493 |
| PKM | pyruvate kinase, muscle | -0.0372325 |
| SPAG9 | sperm associated antigen 9 | -0.0370556 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0366336 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0365036 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0360838 |
| MAP4 | microtubule-associated protein 4 | -0.0348427 |
| CDH13 | cadherin 13 | -0.0330827 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0330016 |
| CUL4A | cullin 4A | -0.0323607 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0322287 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0320318 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0312401 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0309709 |
| CLTC | clathrin, heavy chain (Hc) | -0.0308832 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0300014 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0297232 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0294988 |
| PDE8A | phosphodiesterase 8A | -0.0293394 |
| PRELID2 | PRELI domain containing 2 | -0.0290927 |
| PRKD3 | protein kinase D3 | -0.0287679 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0285182 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0284096 |
| EGFR | epidermal growth factor receptor | -0.0275919 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0259787 |
| AFF4 | AF4/FMR2 family, member 4 | -0.025169 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0250946 |
| B2M | beta-2-microglobulin | -0.0250015 |
| RPL26 | ribosomal protein L26 | -0.0244892 |
| RTN4 | reticulon 4 | -0.024233 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0233016 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0229709 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0217746 |
| TLK1 | tousled-like kinase 1 | -0.0216782 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0214917 |
| RPS19 | ribosomal protein S19 | -0.021339 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0212261 |
