| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Entecavir (monohydrate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL35A | ribosomal protein L35a | 0.0660962 |
| USP3 | ubiquitin specific peptidase 3 | 0.0606067 |
| MT2A | metallothionein 2A | 0.0584634 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0525288 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0494655 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0485383 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0474882 |
| ZNF292 | zinc finger protein 292 | 0.0447817 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0440289 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0428383 |
| DIAPH3 | diaphanous-related formin 3 | 0.0407396 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0386626 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0385991 |
| PCBP2 | poly(rC) binding protein 2 | 0.0375338 |
| PHIP | pleckstrin homology domain interacting protein | 0.0374172 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0373578 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.037001 |
| RPL23 | ribosomal protein L23 | 0.0363945 |
| ATP13A3 | ATPase type 13A3 | 0.0363769 |
| S100A2 | S100 calcium binding protein A2 | 0.0363285 |
| RBM25 | RNA binding motif protein 25 | 0.0360646 |
| HMGA1 | high mobility group AT-hook 1 | 0.0360164 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.036004 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0358157 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0355386 |
| RPLP1 | ribosomal protein, large, P1 | 0.0347502 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0346042 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0341384 |
| PTK2 | protein tyrosine kinase 2 | 0.0337814 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0327037 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0320398 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0309714 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0309437 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0304199 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0299759 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0299618 |
| HLA-A | major histocompatibility complex, class I, A | 0.0295905 |
| RLF | rearranged L-myc fusion | 0.0295773 |
| RPL36 | ribosomal protein L36 | 0.0294115 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0288168 |
| TMSB10 | thymosin beta 10 | 0.0288063 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0286953 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0284539 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.028369 |
| MTF2 | metal response element binding transcription factor 2 | 0.0283535 |
| NUP58 | nucleoporin 58 | 0.0283212 |
| B2M | beta-2-microglobulin | 0.028276 |
| RPL30 | ribosomal protein L30 | 0.0282482 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0281588 |
| RPLP0 | ribosomal protein, large, P0 | 0.0279196 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0279195 |
| CCNL1 | cyclin L1 | 0.0268352 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0266555 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.026634 |
| PARD3 | par-3 family cell polarity regulator | 0.0266018 |
| POU2F1 | POU class 2 homeobox 1 | 0.0265271 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0261066 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0259907 |
| TXNRD1 | thioredoxin reductase 1 | 0.0258826 |
| FOXO3 | forkhead box O3 | 0.025866 |
| KIF20B | kinesin family member 20B | 0.0257866 |
| PCNX1 | pecanex 1 | 0.0255452 |
| TMEM87A | transmembrane protein 87A | 0.0253399 |
| TPI1 | triosephosphate isomerase 1 | 0.0252264 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0252192 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0250829 |
| OLA1 | Obg-like ATPase 1 | 0.0249838 |
| RBM39 | RNA binding motif protein 39 | 0.0249173 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0248912 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0248502 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0248457 |
| RPS21 | ribosomal protein S21 | 0.0247086 |
| RNF145 | ring finger protein 145 | 0.0244405 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0243219 |
| MED13 | mediator complex subunit 13 | 0.0243213 |
| ECT2 | epithelial cell transforming 2 | 0.0242367 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0242082 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0241533 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.023964 |
| RPL13A | ribosomal protein L13a | 0.0238042 |
| CDC73 | cell division cycle 73 | 0.0237926 |
| NOP58 | NOP58 ribonucleoprotein | 0.0236231 |
| WDR43 | WD repeat domain 43 | 0.0235937 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0235278 |
| RHOA | ras homolog family member A | 0.0233329 |
| RPS4X | ribosomal protein S4, X-linked | 0.0232702 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0232416 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0228165 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.022779 |
| LAMB3 | laminin, beta 3 | 0.0225148 |
| PFN1 | profilin 1 | 0.0224689 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | 0.0224616 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0222788 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0222586 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0221802 |
| FANCI | Fanconi anemia, complementation group I | 0.0221652 |
| DEK | DEK proto-oncogene | 0.0220764 |
| RTN4 | reticulon 4 | 0.0220281 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0219493 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.021908 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.144831 |
| FRMD6 | FERM domain containing 6 | -0.130153 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.100413 |
| ZNF438 | zinc finger protein 438 | -0.0980266 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0864797 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0855292 |
| FRMD4A | FERM domain containing 4A | -0.0788786 |
| RPS2 | ribosomal protein S2 | -0.0755514 |
| NABP1 | nucleic acid binding protein 1 | -0.0717734 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0713542 |
| HMGA2 | high mobility group AT-hook 2 | -0.0700208 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0659766 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0651672 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0636206 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0620786 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0617276 |
| RPL7 | ribosomal protein L7 | -0.0554238 |
| MTAP | methylthioadenosine phosphorylase | -0.0539133 |
| AHNAK | AHNAK nucleoprotein | -0.0511447 |
| SET | SET nuclear proto-oncogene | -0.0493969 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0488153 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0486741 |
| STC1 | stanniocalcin 1 | -0.048632 |
| RPL3 | ribosomal protein L3 | -0.0467969 |
| EFNB2 | ephrin-B2 | -0.0448654 |
| CLTC | clathrin, heavy chain (Hc) | -0.0445218 |
| TTR | transthyretin | -0.0436468 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0434549 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0422322 |
| ASPH | aspartate beta-hydroxylase | -0.0417521 |
| HDAC9 | histone deacetylase 9 | -0.0413705 |
| NAV3 | neuron navigator 3 | -0.0410592 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0387449 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0385142 |
| CAPRIN2 | caprin family member 2 | -0.0378491 |
| CANX | calnexin | -0.0372068 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0368513 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0355688 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0349081 |
| PAPOLA | poly(A) polymerase alpha | -0.0342679 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0335919 |
| SP100 | SP100 nuclear antigen | -0.0333963 |
| TPM4 | tropomyosin 4 | -0.0330091 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0327561 |
| INTS6 | integrator complex subunit 6 | -0.0326439 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0321899 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0320494 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0318049 |
| NAV2 | neuron navigator 2 | -0.0315853 |
| TPM3 | tropomyosin 3 | -0.031502 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.031056 |
| GOLGB1 | golgin B1 | -0.0310319 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0305411 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0304103 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0303069 |
| CUX1 | cut-like homeobox 1 | -0.0290506 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0289579 |
| RPS18 | ribosomal protein S18 | -0.0288915 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0287151 |
| RPL7A | ribosomal protein L7a | -0.0285781 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0285646 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0281576 |
| PCNX4 | pecanex 4 | -0.028086 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0279218 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0278141 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0277751 |
| PTMA | prothymosin, alpha | -0.0272149 |
| PGK1 | phosphoglycerate kinase 1 | -0.0272041 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.027157 |
| BPTF | bromodomain PHD finger transcription factor | -0.0271103 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.026889 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0267649 |
| UBC | ubiquitin C | -0.0259744 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0256556 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0253908 |
| RPL4 | ribosomal protein L4 | -0.0250396 |
| FLNB | filamin B, beta | -0.0250301 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0249926 |
| TAOK1 | TAO kinase 1 | -0.0247472 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0244845 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0243995 |
| SETX | senataxin | -0.0242623 |
| TRIM44 | tripartite motif containing 44 | -0.0242037 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.024113 |
| DST | dystonin | -0.0238518 |
| STK4 | serine/threonine kinase 4 | -0.02382 |
| ZNF706 | zinc finger protein 706 | -0.0235427 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.023541 |
| SGMS2 | sphingomyelin synthase 2 | -0.0234522 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0234201 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0231216 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0231116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0230512 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0225294 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0223096 |
| AEBP2 | AE binding protein 2 | -0.0222678 |
| DSG2 | desmoglein 2 | -0.0221363 |
| PRKCE | protein kinase C, epsilon | -0.0218545 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0218124 |
| ATM | ATM serine/threonine kinase | -0.0217621 |
