| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.119173 |
| NDRG1 | N-myc downstream regulated 1 | 0.102179 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.095425 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0831718 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0676108 |
| MCL1 | myeloid cell leukemia 1 | 0.0645912 |
| RORA | RAR-related orphan receptor A | 0.0622589 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0562661 |
| DTNA | dystrobrevin, alpha | 0.0498973 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0449012 |
| CA8 | carbonic anhydrase VIII | 0.0439491 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0439214 |
| FAM13A | family with sequence similarity 13, member A | 0.0419871 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.039135 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0382395 |
| ZNF292 | zinc finger protein 292 | 0.0365764 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0334999 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0328756 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0310408 |
| DENND1A | DENN/MADD domain containing 1A | 0.0295457 |
| MAP1B | microtubule-associated protein 1B | 0.0286597 |
| NELL1 | NEL-like 1 (chicken) | 0.0269338 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0267447 |
| ENO1 | enolase 1, (alpha) | 0.0267093 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.026415 |
| CCNL1 | cyclin L1 | 0.0259114 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0257368 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.025532 |
| VEGFA | vascular endothelial growth factor A | 0.0255287 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0253523 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0252745 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0250982 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0250972 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0239689 |
| NUP58 | nucleoporin 58 | 0.023943 |
| STC1 | stanniocalcin 1 | 0.0238698 |
| CHGB | chromogranin B | 0.0237357 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0236058 |
| PCBP2 | poly(rC) binding protein 2 | 0.0235183 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0232181 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0231435 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0230906 |
| CDC27 | cell division cycle 27 | 0.0230749 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0228584 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0226681 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0222588 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0222563 |
| TXNIP | thioredoxin interacting protein | 0.0220828 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0216351 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0214455 |
| NBAS | neuroblastoma amplified sequence | 0.0207386 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.02064 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0205395 |
| CEP152 | centrosomal protein 152kDa | 0.0204982 |
| LDHA | lactate dehydrogenase A | 0.0204662 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0204342 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.0199801 |
| MSN | moesin | 0.0199459 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0196766 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0196658 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0196464 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0196076 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0192085 |
| XPO1 | exportin 1 | 0.0191338 |
| APP | amyloid beta (A4) precursor protein | 0.0190186 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0188221 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0185315 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0183577 |
| MED13L | mediator complex subunit 13-like | 0.0182924 |
| PTK2 | protein tyrosine kinase 2 | 0.0182232 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0181622 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0180211 |
| TPM3 | tropomyosin 3 | 0.0179827 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0176624 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0176609 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0173793 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0172888 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0172876 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0172749 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0172607 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0172501 |
| LSAMP | limbic system-associated membrane protein | 0.0171936 |
| ESRRG | estrogen-related receptor gamma | 0.0171744 |
| ASPH | aspartate beta-hydroxylase | 0.0171212 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0170768 |
| DOCK5 | dedicator of cytokinesis 5 | 0.016857 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.016562 |
| RTN4 | reticulon 4 | 0.0164589 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0164491 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0162212 |
| HMGB3 | high mobility group box 3 | 0.0161977 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0160158 |
| CENPF | centromere protein F, 350/400kDa | 0.0160131 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0158018 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0158005 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0156775 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0156531 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0155918 |
| RUNX1 | runt-related transcription factor 1 | 0.0155501 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.0153197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.256944 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.110546 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0699118 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0688318 |
| CNKSR3 | CNKSR family member 3 | -0.0649221 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0617922 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0598968 |
| FGF14 | fibroblast growth factor 14 | -0.0597804 |
| RIT2 | Ras-like without CAAX 2 | -0.0578317 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0567059 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.055961 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0527489 |
| AOPEP | aminopeptidase O (putative) | -0.0509802 |
| SNTG1 | syntrophin, gamma 1 | -0.0477235 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0473204 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0470138 |
| SMYD3 | SET and MYND domain containing 3 | -0.0465738 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0427493 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0414067 |
| SIK2 | salt-inducible kinase 2 | -0.0407687 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.0393734 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0360497 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0353126 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.035106 |
| PEG10 | paternally expressed 10 | -0.0348975 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0347998 |
| COL22A1 | collagen, type XXII, alpha 1 | -0.0346179 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0344342 |
| TOX | thymocyte selection-associated high mobility group box | -0.0339852 |
| ZNF804A | zinc finger protein 804A | -0.0333891 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0331719 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 | -0.0326928 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.0320069 |
| MT2A | metallothionein 2A | -0.0319229 |
| NBEA | neurobeachin | -0.0313665 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0308351 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.0302663 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0301546 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0300164 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.028908 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0286393 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.028597 |
| GPC5 | glypican 5 | -0.0282427 |
| KIAA0825 | KIAA0825 | -0.0275969 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0269513 |
| MAP7 | microtubule-associated protein 7 | -0.0260905 |
| RPS6 | ribosomal protein S6 | -0.025458 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0245488 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0238729 |
| INHBA | inhibin, beta A | -0.0238679 |
| FTL | ferritin, light polypeptide | -0.0236548 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0231846 |
| PHF14 | PHD finger protein 14 | -0.0229825 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0226598 |
| FUS | FUS RNA binding protein | -0.0225448 |
| TMSB4X | thymosin beta 4, X-linked | -0.0224842 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0219368 |
| VAV2 | vav 2 guanine nucleotide exchange factor | -0.0218569 |
| FOXC1 | forkhead box C1 | -0.021834 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 | -0.0214057 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0212202 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.0210649 |
| H1-0 | H1.0 linker histone | -0.0209803 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0208841 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0207664 |
| RALYL | RALY RNA binding protein-like | -0.020572 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0205336 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | -0.0204943 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0204882 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0199336 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0197165 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0195687 |
| TRIM9 | tripartite motif containing 9 | -0.0195311 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0195034 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.0194189 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0192347 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | -0.0191021 |
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | -0.0190351 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0189465 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0188913 |
| RPL26 | ribosomal protein L26 | -0.018741 |
| RNF213 | ring finger protein 213 | -0.01872 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | -0.0183404 |
| RPS27A | ribosomal protein S27a | -0.0181194 |
| CORO1C | coronin, actin binding protein, 1C | -0.0180329 |
| TRIM16 | tripartite motif containing 16 | -0.0179917 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0176349 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0176228 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.017388 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.0171636 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0170714 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0170553 |
| RPL6 | ribosomal protein L6 | -0.0170307 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0170166 |
| SYT1 | synaptotagmin I | -0.017 |
| RPL35A | ribosomal protein L35a | -0.0167027 |
| MMP26 | matrix metallopeptidase 26 | -0.0165839 |
| ABI2 | abl-interactor 2 | -0.0164837 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.0163171 |
| CALCA | calcitonin-related polypeptide alpha | -0.0162101 |
