Entecavir (monohydrate)_SK-MEL-2 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Entecavir (monohydrate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Entecavir (monohydrate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FN1 fibronectin 1 0.133287
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0911771
FMN1 formin 1 0.0707693
SPAG9 sperm associated antigen 9 0.0592317
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0589939
FNDC3B fibronectin type III domain containing 3B 0.0586283
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0558878
PRELID2 PRELI domain containing 2 0.0520094
NLGN1 neuroligin 1 0.051118
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0476438
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0442654
MSI2 musashi RNA-binding protein 2 0.0440048
OGA O-GlcNAcase 0.0422808
CANX calnexin 0.0421064
BBX bobby sox homolog (Drosophila) 0.0410217
ASPH aspartate beta-hydroxylase 0.0409281
ICAM1 intercellular adhesion molecule 1 0.0406091
FMNL2 formin-like 2 0.0399984
PDE4D phosphodiesterase 4D, cAMP-specific 0.0399977
ELL2 elongation factor, RNA polymerase II, 2 0.0397039
NAMPT nicotinamide phosphoribosyltransferase 0.0373407
KDM3A lysine (K)-specific demethylase 3A 0.0365245
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0360509
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0356543
RERE arginine-glutamic acid dipeptide (RE) repeats 0.035585
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0345083
ZFAND3 zinc finger, AN1-type domain 3 0.0341578
IGF1R insulin-like growth factor 1 receptor 0.0341351
CFAP20DC CFAP20 domain containing 0.0327648
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0325866
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0325696
SETD5 SET domain containing 5 0.0324266
ZNF292 zinc finger protein 292 0.0321721
ESYT2 extended synaptotagmin-like protein 2 0.0321657
JMJD1C jumonji domain containing 1C 0.032036
MAP4 microtubule-associated protein 4 0.0318786
NAV2 neuron navigator 2 0.0318443
SFTPA2 surfactant protein A2 0.0312842
PGK1 phosphoglycerate kinase 1 0.031219
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0311883
HELZ helicase with zinc finger 0.0310017
ANKRD11 ankyrin repeat domain 11 0.030925
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0305434
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0305097
WSB1 WD repeat and SOCS box containing 1 0.0300407
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.0299613
ANLN anillin, actin binding protein 0.0291856
RBM39 RNA binding motif protein 39 0.0291509
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.028939
ZMYND8 zinc finger, MYND-type containing 8 0.0288698
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0285182
CCDC47 coiled-coil domain containing 47 0.028139
ANGPTL4 angiopoietin-like 4 0.0273765
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 0.0271206
FLNB filamin B, beta 0.0270752
AHNAK AHNAK nucleoprotein 0.0270674
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0269772
RAD51B RAD51 paralog B 0.0268533
AKAP13 A kinase (PRKA) anchor protein 13 0.0264721
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0261959
WWOX WW domain containing oxidoreductase 0.026059
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0260291
SUCO SUN domain containing ossification factor 0.0256098
SLC39A11 solute carrier family 39, member 11 0.0253155
INPP5F inositol polyphosphate-5-phosphatase F 0.0250583
LRMDA leucine rich melanocyte differentiation associated 0.0248462
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0247518
RAB1A RAB1A, member RAS oncogene family 0.0246879
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0245883
YEATS2 YEATS domain containing 2 0.0244569
KMT2C lysine (K)-specific methyltransferase 2C 0.0244122
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0240295
STAG2 stromal antigen 2 0.0239396
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0239239
MORF4L2 mortality factor 4 like 2 0.0238989
FYN FYN proto-oncogene, Src family tyrosine kinase 0.0235642
AKAP10 A kinase (PRKA) anchor protein 10 0.0235391
WWTR1 WW domain containing transcription regulator 1 0.0234833
FHIT fragile histidine triad 0.0234343
NPEPPS aminopeptidase puromycin sensitive 0.0233863
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0233448
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0233293
TM4SF1 transmembrane 4 L six family member 1 0.0231486
MED13L mediator complex subunit 13-like 0.0230343
SSH1 slingshot protein phosphatase 1 0.0228988
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0228765
MAP2K1 mitogen-activated protein kinase kinase 1 0.0228685
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0227674
KMT2E lysine (K)-specific methyltransferase 2E 0.0227083
CADM1 cell adhesion molecule 1 0.022639
AFF4 AF4/FMR2 family, member 4 0.0226146
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0224874
TXNRD1 thioredoxin reductase 1 0.0224
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.0223486
WAC WW domain containing adaptor with coiled-coil 0.0221913
PTK2 protein tyrosine kinase 2 0.0220791
PHF21A PHD finger protein 21A 0.0220763
UBE2H ubiquitin-conjugating enzyme E2H 0.022036
BRWD3 bromodomain and WD repeat domain containing 3 0.0219077
TFG TRK-fused gene 0.0218395

decreased expression

Symbol Name Standardized Value
VIM vimentin -0.122956
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0858182
MT2A metallothionein 2A -0.0538754
RPL35A ribosomal protein L35a -0.0535274
RPS3 ribosomal protein S3 -0.0505136
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.046589
FTL ferritin, light polypeptide -0.0447629
TMSB10 thymosin beta 10 -0.0447068
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0435904
RPS6 ribosomal protein S6 -0.0408587
POTEF POTE ankyrin domain family, member F -0.0373473
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.03354
RPL23 ribosomal protein L23 -0.0328575
ACTG1 actin gamma 1 -0.0321614
HDAC9 histone deacetylase 9 -0.0300936
HMGA1 high mobility group AT-hook 1 -0.0250297
RPS8 ribosomal protein S8 -0.0242873
RPL19 ribosomal protein L19 -0.0236163
LINC02798 long intergenic non-protein coding RNA 2798 -0.0232924
FILIP1 filamin A interacting protein 1 -0.022162
RPS14 ribosomal protein S14 -0.0218936
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -0.0210729
TP63 tumor protein p63 -0.0210691
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0209033
RPL31 ribosomal protein L31 -0.0204071
LSAMP limbic system-associated membrane protein -0.0203927
RPL27 ribosomal protein L27 -0.0203645
CCND1 cyclin D1 -0.0202245
S100A9 S100 calcium binding protein A9 -0.0201482
RPS13 ribosomal protein S13 -0.0199242
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.019879
RPL12 ribosomal protein L12 -0.0194288
RASAL2 RAS protein activator like 2 -0.0192078
IGFBP3 insulin-like growth factor binding protein 3 -0.0190745
RPS19 ribosomal protein S19 -0.0189051
RPS4X ribosomal protein S4, X-linked -0.0188261
RPS23 ribosomal protein S23 -0.018229
RPL34 ribosomal protein L34 -0.0178357
RPL32 ribosomal protein L32 -0.0177742
RPS21 ribosomal protein S21 -0.0176534
RPLP2 ribosomal protein, large, P2 -0.0175866
CDK6 cyclin-dependent kinase 6 -0.017562
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0168364
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0158565
RPL28 ribosomal protein L28 -0.0152867
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -0.0152535
RPL36 ribosomal protein L36 -0.015216
RPS27 ribosomal protein S27 -0.0151793
EEF2 eukaryotic translation elongation factor 2 -0.0148669
AKAP9 A kinase (PRKA) anchor protein 9 -0.0145393
NACA nascent polypeptide-associated complex alpha subunit -0.0143705
RACK1 receptor for activated C kinase 1 -0.0143436
RPS11 ribosomal protein S11 -0.0142679
TOP1 topoisomerase (DNA) I -0.0142415
RPS16 ribosomal protein S16 -0.0141475
LMNA lamin A/C -0.013961
RPL7 ribosomal protein L7 -0.0137385
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0132228
RPL9 ribosomal protein L9 -0.0130931
WDR27 WD repeat domain 27 -0.0130733
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.0129149
FRMD5 FERM domain containing 5 -0.0129021
CCDC88A coiled-coil domain containing 88A -0.0128807
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0128294
ENO2 enolase 2 (gamma, neuronal) -0.0128022
RPL11 ribosomal protein L11 -0.0127718
PKM pyruvate kinase, muscle -0.0126922
IFITM3 interferon induced transmembrane protein 3 -0.0124556
WNT2B wingless-type MMTV integration site family, member 2B -0.0123781
HSPB1 heat shock 27kDa protein 1 -0.0121572
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0121148
KTN1 kinectin 1 (kinesin receptor) -0.0119564
RPS10 ribosomal protein S10 -0.0119101
RPL35 ribosomal protein L35 -0.0119061
CYB5R3 cytochrome b5 reductase 3 -0.0117621
RPS27A ribosomal protein S27a -0.0117156
RPS15 ribosomal protein S15 -0.0116541
RPL36A ribosomal protein L36a -0.0115684
TPI1 triosephosphate isomerase 1 -0.0115501
TAGLN2 transgelin 2 -0.0114403
FAM193A family with sequence similarity 193, member A -0.0114237
HLA-A major histocompatibility complex, class I, A -0.0113797
RGS5 regulator of G-protein signaling 5 -0.0113723
GRIK5 glutamate receptor, ionotropic, kainate 5 -0.0113649
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -0.0113142
EGR1 early growth response 1 -0.0110971
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0110768
RPS5 ribosomal protein S5 -0.0110636
CBX3 chromobox homolog 3 -0.0109234
RUNX1 runt-related transcription factor 1 -0.0109154
RPL38 ribosomal protein L38 -0.0107954
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0107717
TSC22D2 TSC22 domain family, member 2 -0.0106702
HDAC8 histone deacetylase 8 -0.0103727
PMP22 peripheral myelin protein 22 -0.0103125
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0101966
ATF4 activating transcription factor 4 -0.0101939
EEF1G eukaryotic translation elongation factor 1 gamma -0.0101756
RPL15 ribosomal protein L15 -0.0101521
SON SON DNA binding protein -0.0101029