| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.13001 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.106081 |
| FN1 | fibronectin 1 | 0.0946364 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0939156 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0841253 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0708572 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0683095 |
| ZNF292 | zinc finger protein 292 | 0.0638571 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0626353 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0587951 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0547654 |
| ATP13A3 | ATPase type 13A3 | 0.0507763 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.050568 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0471532 |
| OGA | O-GlcNAcase | 0.0470244 |
| GOLGA4 | golgin A4 | 0.0455592 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0447771 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0428922 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0425155 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0420177 |
| SPAG9 | sperm associated antigen 9 | 0.0419909 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0402389 |
| ARRDC3 | arrestin domain containing 3 | 0.0397525 |
| PCBP2 | poly(rC) binding protein 2 | 0.0389986 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0359575 |
| RTN4 | reticulon 4 | 0.0356669 |
| ANLN | anillin, actin binding protein | 0.035448 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0351848 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0347848 |
| MATR3 | matrin 3 | 0.0342581 |
| CCNL1 | cyclin L1 | 0.0341565 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0339953 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0339314 |
| RPS6 | ribosomal protein S6 | 0.0336994 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0326944 |
| RBM39 | RNA binding motif protein 39 | 0.0325692 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0320715 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0314402 |
| HELZ | helicase with zinc finger | 0.0313208 |
| WTAP | Wilms tumor 1 associated protein | 0.0311928 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0311458 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0308776 |
| PHIP | pleckstrin homology domain interacting protein | 0.0300249 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0291882 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0288971 |
| POTEF | POTE ankyrin domain family, member F | 0.0286604 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0283802 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0278094 |
| DSTN | destrin (actin depolymerizing factor) | 0.0276165 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0274189 |
| TXNIP | thioredoxin interacting protein | 0.0273708 |
| DIAPH3 | diaphanous-related formin 3 | 0.0268693 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0267103 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0266691 |
| PGK1 | phosphoglycerate kinase 1 | 0.0266079 |
| SRGN | serglycin | 0.0264568 |
| SNX9 | sorting nexin 9 | 0.0260763 |
| B2M | beta-2-microglobulin | 0.025529 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0254178 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0253102 |
| RPS4X | ribosomal protein S4, X-linked | 0.0252946 |
| ANXA2 | annexin A2 | 0.0250287 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0247855 |
| RPL23 | ribosomal protein L23 | 0.0247231 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0247186 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0246482 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0245309 |
| RPLP0 | ribosomal protein, large, P0 | 0.0244 |
| SERINC1 | serine incorporator 1 | 0.0242944 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0242064 |
| RLF | rearranged L-myc fusion | 0.0240733 |
| MSN | moesin | 0.0238323 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0237197 |
| SFTPA2 | surfactant protein A2 | 0.023459 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0234066 |
| ANXA5 | annexin A5 | 0.0226018 |
| TMEM123 | transmembrane protein 123 | 0.0224769 |
| TFG | TRK-fused gene | 0.0223852 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0223665 |
| JMJD1C | jumonji domain containing 1C | 0.0223351 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0218978 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0217177 |
| DEK | DEK proto-oncogene | 0.0214322 |
| NUP153 | nucleoporin 153kDa | 0.0213285 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0211783 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0211419 |
| NEK7 | NIMA-related kinase 7 | 0.021136 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0210794 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0210709 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0210554 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0209877 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0207421 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0205379 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0203792 |
| DENND4C | DENN/MADD domain containing 4C | 0.0203408 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0202342 |
| EZR | ezrin | 0.0201956 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0200595 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.02005 |
| KLF6 | Kruppel-like factor 6 | 0.0199879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.150014 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.140163 |
| GLIS3 | GLIS family zinc finger 3 | -0.126573 |
| HMGA2 | high mobility group AT-hook 2 | -0.0935767 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0904366 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0806069 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0772877 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0664686 |
| CDH13 | cadherin 13 | -0.0633899 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0626416 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0621088 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0579296 |
| INTS6 | integrator complex subunit 6 | -0.0567868 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0552818 |
| NAV1 | neuron navigator 1 | -0.05192 |
| VCL | vinculin | -0.0515315 |
| HDAC9 | histone deacetylase 9 | -0.0508146 |
| PDE10A | phosphodiesterase 10A | -0.0503446 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0499457 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0497894 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0497259 |
| DST | dystonin | -0.0481459 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0480176 |
| CD44 | CD44 molecule (Indian blood group) | -0.047802 |
| BICC1 | BicC family RNA binding protein 1 | -0.0472781 |
| TNS3 | tensin 3 | -0.0469716 |
| EGFR | epidermal growth factor receptor | -0.0462261 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0422723 |
| DIAPH2 | diaphanous-related formin 2 | -0.0407551 |
| COL5A1 | collagen, type V, alpha 1 | -0.0406173 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0399618 |
| RAI14 | retinoic acid induced 14 | -0.0390045 |
| TMEM132D | transmembrane protein 132D | -0.0386645 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.038491 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0384489 |
| ATXN1 | ataxin 1 | -0.0380564 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0375985 |
| ASPH | aspartate beta-hydroxylase | -0.0361518 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0355256 |
| IER3 | immediate early response 3 | -0.0351829 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0348028 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0337088 |
| FAM20C | family with sequence similarity 20, member C | -0.0332859 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.033126 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0326704 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0313786 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0313277 |
| RAD51B | RAD51 paralog B | -0.0306846 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0304616 |
| HLA-B | major histocompatibility complex, class I, B | -0.0300807 |
| SQSTM1 | sequestosome 1 | -0.0280385 |
| EFNA5 | ephrin-A5 | -0.0277682 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0276719 |
| KYNU | kynureninase | -0.0271152 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0268336 |
| NABP1 | nucleic acid binding protein 1 | -0.0268275 |
| RNF213 | ring finger protein 213 | -0.0267579 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0266914 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0264998 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0260437 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.025959 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0254605 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.025415 |
| NCKAP5 | NCK-associated protein 5 | -0.0250993 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.025043 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0249176 |
| TMSB10 | thymosin beta 10 | -0.0245347 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0239209 |
| EHBP1 | EH domain binding protein 1 | -0.0238945 |
| SEPTIN9 | septin 9 | -0.0237137 |
| VEGFA | vascular endothelial growth factor A | -0.0236301 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0224602 |
| C3 | complement component 3 | -0.0224423 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0220176 |
| AHNAK | AHNAK nucleoprotein | -0.0218166 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0216709 |
| TENM2 | teneurin transmembrane protein 2 | -0.0216708 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.021465 |
| CLMP | CXADR-like membrane protein | -0.0209674 |
| WFDC10B | WAP four-disulfide core domain 10B | -0.0209343 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0208105 |
| SVIL | supervillin | -0.0208012 |
| CTSD | cathepsin D | -0.0207977 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0206795 |
| TPM1 | tropomyosin 1 (alpha) | -0.0204422 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0202148 |
| FBXO11 | F-box protein 11 | -0.0199995 |
| GOLGB1 | golgin B1 | -0.0199892 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0199198 |
| PALLD | palladin, cytoskeletal associated protein | -0.0199183 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0197857 |
| PRKCA | protein kinase C, alpha | -0.0197776 |
| BNC2 | basonuclin 2 | -0.0195407 |
| MLPH | melanophilin | -0.019201 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0190603 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0189328 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0188661 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0188407 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0187855 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0187216 |