| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.221164 |
| FN1 | fibronectin 1 | 0.108817 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.102481 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0881267 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0828247 |
| CDH13 | cadherin 13 | 0.077866 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0682621 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0601089 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0586994 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0568081 |
| COL1A2 | collagen, type I, alpha 2 | 0.0555502 |
| PRSS23 | protease, serine, 23 | 0.0542055 |
| LAMB3 | laminin, beta 3 | 0.0538935 |
| FAM13A | family with sequence similarity 13, member A | 0.0509717 |
| LOX | lysyl oxidase | 0.0499392 |
| LOXL2 | lysyl oxidase-like 2 | 0.0491377 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0476648 |
| VIM | vimentin | 0.0475919 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0473394 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0463695 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0459311 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0454677 |
| LDHA | lactate dehydrogenase A | 0.0427882 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0426273 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0413106 |
| NRXN3 | neurexin 3 | 0.0407376 |
| EFNA5 | ephrin-A5 | 0.0391807 |
| ENO1 | enolase 1, (alpha) | 0.0390153 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0387366 |
| ASPH | aspartate beta-hydroxylase | 0.0382689 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0381813 |
| HMGA2 | high mobility group AT-hook 2 | 0.0369605 |
| COL1A1 | collagen, type I, alpha 1 | 0.0367055 |
| FLNB | filamin B, beta | 0.0351974 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.03489 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0348317 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0339842 |
| SPAG9 | sperm associated antigen 9 | 0.0335812 |
| HELZ | helicase with zinc finger | 0.0331137 |
| FTO | fat mass and obesity associated | 0.0330125 |
| ATP13A3 | ATPase type 13A3 | 0.0321925 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.030986 |
| PRELID2 | PRELI domain containing 2 | 0.0307913 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0306118 |
| STC1 | stanniocalcin 1 | 0.0303729 |
| COL5A1 | collagen, type V, alpha 1 | 0.0302525 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0301195 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0298762 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.029446 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.029156 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0290881 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0290627 |
| RUNX1 | runt-related transcription factor 1 | 0.0286982 |
| TNS3 | tensin 3 | 0.0285936 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0285192 |
| EZR | ezrin | 0.0281813 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0280703 |
| IL6 | interleukin 6 | 0.0278473 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0277481 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0274577 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0272975 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0269973 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0268467 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0267628 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0267107 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0267084 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0265924 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0265282 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0263024 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0262826 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0262631 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0256334 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0254552 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0250341 |
| MLEC | malectin | 0.0248714 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.024515 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0244612 |
| NUCB2 | nucleobindin 2 | 0.0244504 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0240598 |
| ANO6 | anoctamin 6 | 0.0240279 |
| AHNAK | AHNAK nucleoprotein | 0.0238047 |
| ZNF638 | zinc finger protein 638 | 0.0237699 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0236327 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0233781 |
| ACTN1 | actinin, alpha 1 | 0.0233303 |
| TUBB | tubulin, beta class I | 0.0232432 |
| SBF2 | SET binding factor 2 | 0.0232137 |
| MTSS1 | metastasis suppressor 1 | 0.0231989 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0230169 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0229776 |
| UTRN | utrophin | 0.0229681 |
| SFTPA2 | surfactant protein A2 | 0.0229103 |
| SEPTIN9 | septin 9 | 0.0228548 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.02284 |
| CBX5 | chromobox homolog 5 | 0.0226541 |
| C1D | C1D nuclear receptor corepressor | 0.0226052 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0225439 |
| BMERB1 | bMERB domain containing 1 | 0.022269 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0220807 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0219573 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.124369 |
| HLA-B | major histocompatibility complex, class I, B | -0.0636235 |
| B2M | beta-2-microglobulin | -0.0620124 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0586438 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0526486 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0495464 |
| H3-3B | H3.3 histone B | -0.0453122 |
| COG5 | component of oligomeric golgi complex 5 | -0.0421084 |
| RPS2 | ribosomal protein S2 | -0.0402037 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0394746 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0371578 |
| RNF24 | ring finger protein 24 | -0.0360692 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0358418 |
| MATR3 | matrin 3 | -0.0354199 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0351517 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0350422 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0347584 |
| CALD1 | caldesmon 1 | -0.0346399 |
| RPL11 | ribosomal protein L11 | -0.0334196 |
| HDLBP | high density lipoprotein binding protein | -0.0331031 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0330798 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0329597 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0311231 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0310762 |
| TPM3 | tropomyosin 3 | -0.0308684 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0307106 |
| LAMB1 | laminin, beta 1 | -0.0305584 |
| NDRG1 | N-myc downstream regulated 1 | -0.030525 |
| RPL26 | ribosomal protein L26 | -0.0301575 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0299944 |
| FUS | FUS RNA binding protein | -0.0296565 |
| TNPO1 | transportin 1 | -0.0295975 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0295803 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0288997 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0287648 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.028717 |
| RINT1 | RAD50 interactor 1 | -0.0287109 |
| TFG | TRK-fused gene | -0.0286386 |
| SETD5 | SET domain containing 5 | -0.0285325 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0284163 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0283489 |
| RPL32 | ribosomal protein L32 | -0.0282807 |
| ANLN | anillin, actin binding protein | -0.028145 |
| ARRDC3 | arrestin domain containing 3 | -0.0281197 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0277484 |
| SMYD3 | SET and MYND domain containing 3 | -0.0275832 |
| SRPK2 | SRSF protein kinase 2 | -0.0272783 |
| SDC4 | syndecan 4 | -0.0271079 |
| HIP1 | huntingtin interacting protein 1 | -0.0271062 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0270951 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0267284 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0264467 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -0.0263854 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.026156 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.026048 |
| KIF5B | kinesin family member 5B | -0.0260162 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0260039 |
| ZNF292 | zinc finger protein 292 | -0.0259464 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0254886 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0254623 |
| WDR45B | WD repeat domain 45B | -0.0253666 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.025353 |
| RYBP | RING1 and YY1 binding protein | -0.0251501 |
| FAM13B | family with sequence similarity 13, member B | -0.0249682 |
| PTN | pleiotrophin | -0.0246057 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0245955 |
| KIF1B | kinesin family member 1B | -0.0245687 |
| GLG1 | golgi glycoprotein 1 | -0.024502 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0244302 |
| PTGES2 | prostaglandin E synthase 2 | -0.0244197 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0244135 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0242644 |
| MAP1B | microtubule-associated protein 1B | -0.0242114 |
| MRTFA | myocardin related transcription factor A | -0.0241909 |
| APP | amyloid beta (A4) precursor protein | -0.0240885 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0239664 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0238926 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0238866 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0237755 |
| RNF130 | ring finger protein 130 | -0.0236754 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0236523 |
| UBAP2 | ubiquitin associated protein 2 | -0.0235969 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0235353 |
| ACTG1 | actin gamma 1 | -0.0234899 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0233882 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0232983 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.02328 |
| GOLGA4 | golgin A4 | -0.0231528 |
| MXD1 | MAX dimerization protein 1 | -0.0230917 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0229765 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0228938 |
| SCAF8 | SR-related CTD-associated factor 8 | -0.0226903 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0226093 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0225845 |
| SFXN1 | sideroflexin 1 | -0.0224548 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.022113 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0219765 |
| TGFB1 | transforming growth factor, beta 1 | -0.0217439 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0217171 |
| TRIM23 | tripartite motif containing 23 | -0.0216932 |