| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entecavir (monohydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entecavir (monohydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0904926 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0807551 |
| TXNIP | thioredoxin interacting protein | 0.0661335 |
| CD109 | CD109 molecule | 0.0504759 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0452807 |
| NRP1 | neuropilin 1 | 0.0448633 |
| TMEM156 | transmembrane protein 156 | 0.0442549 |
| RUNX2 | runt-related transcription factor 2 | 0.043314 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0390309 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0380069 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0368328 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0368152 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0320208 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0300564 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.029819 |
| CCNL1 | cyclin L1 | 0.0298115 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0291721 |
| RTN4 | reticulon 4 | 0.0290891 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0289708 |
| WDR26 | WD repeat domain 26 | 0.0287732 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0286246 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0275536 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0265168 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0261484 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0258668 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0252119 |
| RNF145 | ring finger protein 145 | 0.0251408 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0250748 |
| PELO | pelota homolog (Drosophila) | 0.0248198 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0247525 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0245845 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0240526 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0238485 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0237972 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0237069 |
| HELZ | helicase with zinc finger | 0.0235581 |
| ADD3 | adducin 3 (gamma) | 0.0227412 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0221873 |
| ITGB5 | integrin, beta 5 | 0.0219675 |
| FAM13A | family with sequence similarity 13, member A | 0.0219373 |
| CAB39 | calcium binding protein 39 | 0.0217538 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0216818 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0214709 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0214564 |
| ERBIN | erbb2 interacting protein | 0.0213472 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0206806 |
| USP12 | ubiquitin specific peptidase 12 | 0.0203421 |
| PRPF8 | pre-mRNA processing factor 8 | 0.02014 |
| COPA | coatomer protein complex, subunit alpha | 0.0199622 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0199499 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0199412 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0198167 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.019726 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0195003 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0194208 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0193892 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0193717 |
| RBM39 | RNA binding motif protein 39 | 0.0192701 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0191692 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0191414 |
| ETNK1 | ethanolamine kinase 1 | 0.0189462 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0189096 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0188568 |
| PDE8A | phosphodiesterase 8A | 0.018813 |
| FBXO32 | F-box protein 32 | 0.0187036 |
| ZNF292 | zinc finger protein 292 | 0.0186464 |
| SMOX | spermine oxidase | 0.0185443 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0185332 |
| SNX13 | sorting nexin 13 | 0.018287 |
| RNF24 | ring finger protein 24 | 0.018151 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0178853 |
| CORO1C | coronin, actin binding protein, 1C | 0.0177553 |
| TMEM87A | transmembrane protein 87A | 0.0176479 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0176023 |
| DIAPH3 | diaphanous-related formin 3 | 0.0174074 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0173304 |
| PRELID2 | PRELI domain containing 2 | 0.0170216 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0170004 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0169246 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.016844 |
| AFDN | afadin, adherens junction formation factor | 0.0168116 |
| TXNRD1 | thioredoxin reductase 1 | 0.0167532 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0167371 |
| AHR | aryl hydrocarbon receptor | 0.0166616 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0166453 |
| SETD5 | SET domain containing 5 | 0.0163851 |
| HNRNPLL | heterogeneous nuclear ribonucleoprotein L-like | 0.0161644 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0161426 |
| DUSP5 | dual specificity phosphatase 5 | 0.0160634 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0158749 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0158124 |
| CCNJL | cyclin J-like | 0.0157229 |
| CDC73 | cell division cycle 73 | 0.0155943 |
| PCBP2 | poly(rC) binding protein 2 | 0.0155732 |
| MSN | moesin | 0.0155569 |
| ATL2 | atlastin GTPase 2 | 0.0155521 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0155111 |
| RCOR3 | REST corepressor 3 | 0.015482 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0154658 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0154182 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.269737 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.249669 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.196089 |
| PTMA | prothymosin, alpha | -0.177175 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.146328 |
| NRG1 | neuregulin 1 | -0.142353 |
| SQSTM1 | sequestosome 1 | -0.137677 |
| CANX | calnexin | -0.127577 |
| VIM | vimentin | -0.105372 |
| S100A6 | S100 calcium binding protein A6 | -0.0904013 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.090284 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0884545 |
| FN1 | fibronectin 1 | -0.0884152 |
| TMSB10 | thymosin beta 10 | -0.0877908 |
| HLA-B | major histocompatibility complex, class I, B | -0.081425 |
| HMGA2 | high mobility group AT-hook 2 | -0.0797088 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0787759 |
| TMSB4X | thymosin beta 4, X-linked | -0.0783656 |
| ASPH | aspartate beta-hydroxylase | -0.0768769 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0761822 |
| FTL | ferritin, light polypeptide | -0.0721647 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0658935 |
| ENO1 | enolase 1, (alpha) | -0.062449 |
| EXT1 | exostosin glycosyltransferase 1 | -0.061602 |
| RPS27A | ribosomal protein S27a | -0.0595987 |
| RACK1 | receptor for activated C kinase 1 | -0.058989 |
| RPL26 | ribosomal protein L26 | -0.058344 |
| MT2A | metallothionein 2A | -0.058172 |
| ACTG1 | actin gamma 1 | -0.0578649 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0541192 |
| INTS6 | integrator complex subunit 6 | -0.0526233 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0521343 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.050213 |
| UBC | ubiquitin C | -0.0498273 |
| S100A10 | S100 calcium binding protein A10 | -0.0491923 |
| RPS8 | ribosomal protein S8 | -0.0488039 |
| AEBP2 | AE binding protein 2 | -0.0481094 |
| RPL37A | ribosomal protein L37a | -0.0477067 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0472606 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0463922 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0453883 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0452039 |
| CALR | calreticulin | -0.0449664 |
| PALLD | palladin, cytoskeletal associated protein | -0.0445572 |
| VCL | vinculin | -0.0444181 |
| RPLP1 | ribosomal protein, large, P1 | -0.0440126 |
| RPS12 | ribosomal protein S12 | -0.0436381 |
| SFTPA2 | surfactant protein A2 | -0.0421701 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0420763 |
| IER3 | immediate early response 3 | -0.0416488 |
| RAI14 | retinoic acid induced 14 | -0.0416232 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0414011 |
| AHNAK | AHNAK nucleoprotein | -0.0408371 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0408234 |
| RPL31 | ribosomal protein L31 | -0.0408227 |
| RPS24 | ribosomal protein S24 | -0.0402626 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0395571 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0387322 |
| LRRC23 | leucine rich repeat containing 23 | -0.0385806 |
| LMNA | lamin A/C | -0.0379249 |
| B2M | beta-2-microglobulin | -0.0372901 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0368335 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0367782 |
| RPL38 | ribosomal protein L38 | -0.0359866 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.035874 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0358344 |
| RPL9 | ribosomal protein L9 | -0.0354558 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0352954 |
| RPL34 | ribosomal protein L34 | -0.0350529 |
| H1-0 | H1.0 linker histone | -0.0349699 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0344336 |
| HDLBP | high density lipoprotein binding protein | -0.0341859 |
| RPL37 | ribosomal protein L37 | -0.0341618 |
| RPS6 | ribosomal protein S6 | -0.0333829 |
| RPS19 | ribosomal protein S19 | -0.0329109 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0319179 |
| GNAS | GNAS complex locus | -0.0318158 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0312735 |
| RPS29 | ribosomal protein S29 | -0.0312057 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0309824 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0309774 |
| RPL35A | ribosomal protein L35a | -0.0303345 |
| RPS5 | ribosomal protein S5 | -0.0300537 |
| HMGA1 | high mobility group AT-hook 1 | -0.0299797 |
| MTDH | metadherin | -0.0297835 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0296877 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0296133 |
| RPS27 | ribosomal protein S27 | -0.0294882 |
| RPS3 | ribosomal protein S3 | -0.0293363 |
| POTEF | POTE ankyrin domain family, member F | -0.0289359 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0288499 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0287081 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0286505 |
| RPL19 | ribosomal protein L19 | -0.0283426 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0281248 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0280688 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0279121 |
| S100A9 | S100 calcium binding protein A9 | -0.0278355 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0277355 |
| RPS21 | ribosomal protein S21 | -0.0275438 |