Entecavir (monohydrate)_SW1417 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Entecavir (monohydrate) perturbation in SW1417 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Entecavir (monohydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha 0.107668
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0724809
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.071589
CCND1 cyclin D1 0.0693798
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0691326
KRT8 keratin 8, type II 0.0678625
RBM39 RNA binding motif protein 39 0.0674058
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.053283
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0527057
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0526563
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0509798
FXR1 fragile X mental retardation, autosomal homolog 1 0.0499738
MATR3 matrin 3 0.0499123
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0484175
NAMPT nicotinamide phosphoribosyltransferase 0.0478206
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0467587
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.0458896
SQSTM1 sequestosome 1 0.0444319
ANXA2 annexin A2 0.0442779
RAB1A RAB1A, member RAS oncogene family 0.0429936
GLS2 glutaminase 2 (liver, mitochondrial) 0.0425447
RAD21 RAD21 homolog (S. pombe) 0.0422141
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0415488
SPAG9 sperm associated antigen 9 0.0414004
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0408446
KRT18 keratin 18, type I 0.0397913
TRA2A transformer 2 alpha homolog (Drosophila) 0.038236
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0377025
NCOA3 nuclear receptor coactivator 3 0.0362431
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0360323
KMT2E lysine (K)-specific methyltransferase 2E 0.0340904
CSNK1A1 casein kinase 1, alpha 1 0.0338194
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0332883
CCNL1 cyclin L1 0.0329935
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 0.0328101
ZNF292 zinc finger protein 292 0.0321593
LMTK2 lemur tyrosine kinase 2 0.0318685
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0313616
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0312553
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0311826
HBP1 HMG-box transcription factor 1 0.0308797
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0305998
PTK2 protein tyrosine kinase 2 0.0303902
NPTN neuroplastin 0.0302363
BZW1 basic leucine zipper and W2 domains 1 0.0301224
PERP PERP, TP53 apoptosis effector 0.0297142
UBQLN1 ubiquilin 1 0.0296815
EPCAM epithelial cell adhesion molecule 0.0296365
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0291493
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.0288421
RHEB Ras homolog enriched in brain 0.0286182
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0283601
IFRD1 interferon-related developmental regulator 1 0.0281659
ATL2 atlastin GTPase 2 0.0275808
GNAS GNAS complex locus 0.0274485
ZNRF3 zinc and ring finger 3 0.0271692
ANKHD1 ankyrin repeat and KH domain containing 1 0.0270691
RBM33 RNA binding motif protein 33 0.026994
USP3 ubiquitin specific peptidase 3 0.0269352
TMEM123 transmembrane protein 123 0.0269278
DIDO1 death inducer-obliterator 1 0.0268919
FBXO11 F-box protein 11 0.0267753
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0266579
RSRC2 arginine/serine-rich coiled-coil 2 0.0264706
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0260013
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0257273
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0257075
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0254063
SET SET nuclear proto-oncogene 0.0252788
MTMR3 myotubularin related protein 3 0.0252518
STAG2 stromal antigen 2 0.0245979
ARHGAP32 Rho GTPase activating protein 32 0.0244523
KDM3A lysine (K)-specific demethylase 3A 0.0244136
PDIA3 protein disulfide isomerase family A, member 3 0.0241119
MEF2A myocyte enhancer factor 2A 0.0238679
DEK DEK proto-oncogene 0.0236515
AFDN afadin, adherens junction formation factor 0.0235654
TPT1 tumor protein, translationally-controlled 1 0.0235213
UBE2H ubiquitin-conjugating enzyme E2H 0.0233874
PCBP2 poly(rC) binding protein 2 0.0233841
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0228951
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0226995
WAC WW domain containing adaptor with coiled-coil 0.0224111
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.0223542
ECT2 epithelial cell transforming 2 0.0223062
RAB10 RAB10, member RAS oncogene family 0.0221364
EZR ezrin 0.0218768
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.0218405
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.02172
EPS8 epidermal growth factor receptor pathway substrate 8 0.0217095
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.0216212
TCERG1 transcription elongation regulator 1 0.0214421
RPS2 ribosomal protein S2 0.0214003
EMP1 epithelial membrane protein 1 0.0213646
NCKAP1 NCK-associated protein 1 0.0212211
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0210164
KDM6A lysine (K)-specific demethylase 6A 0.0209329
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.0209065
CDK17 cyclin-dependent kinase 17 0.0208158
TXNRD1 thioredoxin reductase 1 0.0207158

decreased expression

Symbol Name Standardized Value
FTL ferritin, light polypeptide -0.178474
TMSB10 thymosin beta 10 -0.0855156
BCL2L1 BCL2-like 1 -0.0657411
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0590007
EGR1 early growth response 1 -0.0570782
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.038341
VCL vinculin -0.0332736
RPS19 ribosomal protein S19 -0.0316658
IFITM3 interferon induced transmembrane protein 3 -0.0295288
NDRG1 N-myc downstream regulated 1 -0.0290556
RPS21 ribosomal protein S21 -0.0288632
RPS13 ribosomal protein S13 -0.0287525
RPL8 ribosomal protein L8 -0.0286488
GOLGA4 golgin A4 -0.028614
NCEH1 neutral cholesterol ester hydrolase 1 -0.0286136
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0282884
MACC1 metastasis associated in colon cancer 1 -0.0282839
RPS6 ribosomal protein S6 -0.0280117
IFITM1 interferon induced transmembrane protein 1 -0.0274758
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.027428
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0267861
PRELID2 PRELI domain containing 2 -0.0257973
RPL32 ribosomal protein L32 -0.0257551
ESYT2 extended synaptotagmin-like protein 2 -0.0257115
EDN1 endothelin 1 -0.0255317
CST3 cystatin C -0.0253843
RPLP2 ribosomal protein, large, P2 -0.0248836
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0244547
RPL23 ribosomal protein L23 -0.0244248
IFI27 interferon, alpha-inducible protein 27 -0.0241948
RPL28 ribosomal protein L28 -0.0241496
RPL36 ribosomal protein L36 -0.0236771
IFI6 interferon, alpha-inducible protein 6 -0.022228
MAML2 mastermind-like 2 (Drosophila) -0.0222072
RPL31 ribosomal protein L31 -0.0219376
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0215294
ROMO1 reactive oxygen species modulator 1 -0.0212018
RPS29 ribosomal protein S29 -0.0210444
MYOF myoferlin -0.0208653
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.0206653
WWC1 WW and C2 domain containing 1 -0.0204825
MX2 MX dynamin-like GTPase 2 -0.0195134
H1-0 H1.0 linker histone -0.0192624
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.0192267
SRRM2 serine/arginine repetitive matrix 2 -0.0187697
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0184853
RPS14 ribosomal protein S14 -0.0182948
MT2A metallothionein 2A -0.0180647
RPL27 ribosomal protein L27 -0.0178085
MYO1E myosin IE -0.0177682
FAT1 FAT atypical cadherin 1 -0.0176483
CLDN4 claudin 4 -0.0175303
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0174512
RPL19 ribosomal protein L19 -0.0174459
RPS15 ribosomal protein S15 -0.0173737
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0171296
S100A9 S100 calcium binding protein A9 -0.0169541
ADM adrenomedullin -0.0168783
ANKRD12 ankyrin repeat domain 12 -0.0166795
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0165797
ACBD3 acyl-CoA binding domain containing 3 -0.0163059
RPL35A ribosomal protein L35a -0.0157872
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0157813
VIM vimentin -0.0156348
ATP5F1E ATP synthase F1 subunit epsilon -0.0155172
SEC61G Sec61 gamma subunit -0.0152961
RPL38 ribosomal protein L38 -0.0149915
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.01495
RPL15 ribosomal protein L15 -0.0148507
RPS10 ribosomal protein S10 -0.0148322
ARHGAP42 Rho GTPase activating protein 42 -0.0148099
MT1X metallothionein 1X -0.0147691
ZNFX1 zinc finger, NFX1-type containing 1 -0.0147134
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0145355
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.0145259
CEMIP cell migration inducing protein, hyaluronan binding -0.0144516
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0143092
SP100 SP100 nuclear antigen -0.0140117
CXXC5 CXXC finger protein 5 -0.0138937
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0137787
RPS11 ribosomal protein S11 -0.0136004
RPL12 ribosomal protein L12 -0.0134026
LOC112694756 uncharaterized LOC112694756 -0.0133214
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0133189
LATS2 large tumor suppressor kinase 2 -0.0131734
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -0.0131375
RPL35 ribosomal protein L35 -0.0130571
KTN1 kinectin 1 (kinesin receptor) -0.01293
CALU calumenin -0.0129045
C6ORF132 chromosome 6 open reading frame 132 -0.0126025
RPS27 ribosomal protein S27 -0.0125264
SHB Src homology 2 domain containing adaptor protein B -0.0124739
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0122664
UBXN4 UBX domain protein 4 -0.0122071
RAB5A RAB5A, member RAS oncogene family -0.012135
GSTP1 glutathione S-transferase pi 1 -0.0121013
PFDN1 prefoldin subunit 1 -0.0120787
TGFA transforming growth factor, alpha -0.012066
RPS25 ribosomal protein S25 -0.0120282
SVIL supervillin -0.0120198