| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entrectinib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Entrectinib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.188309 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.12903 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.105795 |
| VIM | vimentin | 0.105151 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.060985 |
| COL1A1 | collagen, type I, alpha 1 | 0.0555743 |
| MAP1B | microtubule-associated protein 1B | 0.0508854 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0452025 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0420187 |
| RPL35A | ribosomal protein L35a | 0.0389433 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0310427 |
| VCL | vinculin | 0.0306222 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0298823 |
| H1-0 | H1.0 linker histone | 0.0288904 |
| FTL | ferritin, light polypeptide | 0.0286113 |
| RPL34 | ribosomal protein L34 | 0.0273053 |
| SEPTIN9 | septin 9 | 0.0272163 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0266949 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0264268 |
| RPL32 | ribosomal protein L32 | 0.0263887 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0259356 |
| MEF2A | myocyte enhancer factor 2A | 0.0257572 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0251235 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0250592 |
| RPS27A | ribosomal protein S27a | 0.0245993 |
| FN1 | fibronectin 1 | 0.0245272 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0238162 |
| RPS6 | ribosomal protein S6 | 0.0227842 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0223254 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0219764 |
| RPL19 | ribosomal protein L19 | 0.0218634 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0211595 |
| ATRNL1 | attractin-like 1 | 0.0209556 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0208181 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0208062 |
| NDRG1 | N-myc downstream regulated 1 | 0.020351 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0203409 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0203357 |
| EGR1 | early growth response 1 | 0.0198408 |
| PLAT | plasminogen activator, tissue | 0.0196443 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0193032 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0192099 |
| RPS3 | ribosomal protein S3 | 0.0187475 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0184904 |
| SIK2 | salt-inducible kinase 2 | 0.0182565 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.0182356 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0182183 |
| GOLGB1 | golgin B1 | 0.0181263 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.018031 |
| GLCCI1 | glucocorticoid induced 1 | 0.0178996 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0176326 |
| RAD51B | RAD51 paralog B | 0.0174829 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0171957 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0170924 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0170917 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0169371 |
| RPS20 | ribosomal protein S20 | 0.0166694 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0166209 |
| LSAMP | limbic system-associated membrane protein | 0.0164978 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0164253 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0163195 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0162071 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0160813 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.015944 |
| RPL35 | ribosomal protein L35 | 0.0158261 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.0157152 |
| RPS14 | ribosomal protein S14 | 0.0156921 |
| CRH | corticotropin releasing hormone | 0.015582 |
| COL3A1 | collagen, type III, alpha 1 | 0.0151736 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0151201 |
| PTMA | prothymosin, alpha | 0.0151191 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0148127 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0147924 |
| RPL36 | ribosomal protein L36 | 0.0147034 |
| RPL13A | ribosomal protein L13a | 0.014343 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.0143348 |
| CALU | calumenin | 0.0141313 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0139434 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0139359 |
| CADM2 | cell adhesion molecule 2 | 0.0138494 |
| PCBP3 | poly(rC) binding protein 3 | 0.0136834 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0136336 |
| GPC5 | glypican 5 | 0.0134171 |
| GDF15 | growth differentiation factor 15 | 0.0134142 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0132912 |
| RPL37 | ribosomal protein L37 | 0.0130141 |
| NCOR2 | nuclear receptor corepressor 2 | 0.012989 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0129662 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0127223 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0127222 |
| RPL27 | ribosomal protein L27 | 0.0126712 |
| ZFP36 | ZFP36 ring finger protein | 0.012592 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0124948 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0124161 |
| PFN1 | profilin 1 | 0.0123041 |
| TOB1 | transducer of ERBB2, 1 | 0.0122386 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.012234 |
| TGFB1 | transforming growth factor, beta 1 | 0.0120884 |
| RPL37A | ribosomal protein L37a | 0.0119635 |
| GAB2 | GRB2-associated binding protein 2 | 0.0119136 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.34029 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.052247 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0517448 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0475702 |
| HELZ | helicase with zinc finger | -0.0376526 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0367807 |
| LPIN1 | lipin 1 | -0.0351982 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0328951 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.032408 |
| FAM13A | family with sequence similarity 13, member A | -0.0316913 |
| SMYD3 | SET and MYND domain containing 3 | -0.0309004 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0306625 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0304277 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0298668 |
| SPAG9 | sperm associated antigen 9 | -0.0287652 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0287019 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.02767 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0273809 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0271931 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0270492 |
| AOPEP | aminopeptidase O (putative) | -0.026342 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0250596 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0247473 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.024261 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0239969 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0238427 |
| PTK2 | protein tyrosine kinase 2 | -0.0235008 |
| PKM | pyruvate kinase, muscle | -0.0234038 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0232206 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0228346 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0226947 |
| RNF213 | ring finger protein 213 | -0.022552 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0225475 |
| ZNF207 | zinc finger protein 207 | -0.021689 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0214964 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0211948 |
| XPO1 | exportin 1 | -0.020601 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0205679 |
| ANKRD28 | ankyrin repeat domain 28 | -0.020499 |
| PCBP2 | poly(rC) binding protein 2 | -0.0204168 |
| PCDH9 | protocadherin 9 | -0.0202893 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0202765 |
| PCNX1 | pecanex 1 | -0.0200541 |
| JMJD1C | jumonji domain containing 1C | -0.02003 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0200082 |
| SUCO | SUN domain containing ossification factor | -0.0197874 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.019656 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0194841 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0193262 |
| DNMBP | dynamin binding protein | -0.0189762 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0187327 |
| NEK7 | NIMA-related kinase 7 | -0.0184834 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0184718 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0184279 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0181987 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0181891 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0180882 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.01807 |
| NF1 | neurofibromin 1 | -0.0180572 |
| SEPTIN7 | septin 7 | -0.0178819 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0176954 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0176783 |
| TLK2 | tousled-like kinase 2 | -0.0175759 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.017557 |
| PHF21A | PHD finger protein 21A | -0.0175238 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0173949 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0173811 |
| DST | dystonin | -0.0173135 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0172878 |
| ENAH | enabled homolog (Drosophila) | -0.0169914 |
| CENPE | centromere protein E, 312kDa | -0.0169613 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0169459 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0169286 |
| DSCAM | Down syndrome cell adhesion molecule | -0.016926 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0169231 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0168958 |
| BBX | bobby sox homolog (Drosophila) | -0.0168634 |
| NBAS | neuroblastoma amplified sequence | -0.0168385 |
| ANO6 | anoctamin 6 | -0.0167323 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0165631 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0165233 |
| SRP54 | signal recognition particle 54kDa | -0.0165055 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0163988 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0162479 |
| PDS5B | PDS5 cohesin associated factor B | -0.0162007 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0161276 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0161143 |
| OGA | O-GlcNAcase | -0.0160178 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0159538 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0159065 |
| PARD3 | par-3 family cell polarity regulator | -0.0158863 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0156625 |
| PDE8A | phosphodiesterase 8A | -0.0155209 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0155157 |
| RIGI | RNA sensor RIG-I | -0.0154575 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0154549 |
| MED13 | mediator complex subunit 13 | -0.0153428 |
| NKTR | natural killer cell triggering receptor | -0.0153228 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0153027 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0152482 |
