| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entrectinib perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entrectinib_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.179628 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0903068 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0476695 |
| CD44 | CD44 molecule (Indian blood group) | 0.0424869 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0412529 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.035697 |
| COL1A1 | collagen, type I, alpha 1 | 0.0356105 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0329802 |
| STC1 | stanniocalcin 1 | 0.0310935 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0292009 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0282212 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0278185 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0265999 |
| CDH13 | cadherin 13 | 0.0255177 |
| COL5A1 | collagen, type V, alpha 1 | 0.0254519 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0228399 |
| HMGA2 | high mobility group AT-hook 2 | 0.0222545 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0214629 |
| MTSS1 | metastasis suppressor 1 | 0.0202778 |
| FBN1 | fibrillin 1 | 0.019805 |
| ECE1 | endothelin converting enzyme 1 | 0.0182674 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0171389 |
| LOXL2 | lysyl oxidase-like 2 | 0.0170708 |
| FAT1 | FAT atypical cadherin 1 | 0.0170123 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0167824 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0166945 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0166472 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.016473 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0161713 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0159594 |
| SMAD3 | SMAD family member 3 | 0.0158327 |
| VCAN | versican | 0.0158269 |
| MAP1B | microtubule-associated protein 1B | 0.0155194 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0151565 |
| GLIS3 | GLIS family zinc finger 3 | 0.0148808 |
| H1-0 | H1.0 linker histone | 0.0146696 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0145803 |
| NAV1 | neuron navigator 1 | 0.0145375 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0145105 |
| CLIC4 | chloride intracellular channel 4 | 0.0144735 |
| PRELID2 | PRELI domain containing 2 | 0.0139933 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.01398 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0134639 |
| HAS2 | hyaluronan synthase 2 | 0.0133801 |
| EFNA5 | ephrin-A5 | 0.0133389 |
| PLEC | plectin | 0.0132532 |
| VCL | vinculin | 0.0127439 |
| RUNX1 | runt-related transcription factor 1 | 0.0126334 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0126156 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.012582 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0121891 |
| NAV2 | neuron navigator 2 | 0.012168 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.012096 |
| ATXN1 | ataxin 1 | 0.0120316 |
| DST | dystonin | 0.0118633 |
| RASA2 | RAS p21 protein activator 2 | 0.0116577 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0112466 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0111873 |
| AHNAK | AHNAK nucleoprotein | 0.0110635 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0108636 |
| DSPP | dentin sialophosphoprotein | 0.0105035 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0102116 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0101788 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0100586 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.00987023 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00975448 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00967985 |
| MSN | moesin | 0.00966722 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0093609 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00922827 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00904804 |
| KIAA1217 | KIAA1217 | 0.00895735 |
| SH3PXD2B | SH3 and PX domains 2B | 0.008909 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.00887517 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00858623 |
| VEGFC | vascular endothelial growth factor C | 0.00841795 |
| RASA3 | RAS p21 protein activator 3 | 0.00839512 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00833841 |
| FER | fer (fps/fes related) tyrosine kinase | 0.00833118 |
| MYO10 | myosin X | 0.00830017 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.00827162 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.00812342 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.00808226 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00785323 |
| FAM20C | family with sequence similarity 20, member C | 0.00776582 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00775716 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00773385 |
| SEPTIN9 | septin 9 | 0.00762616 |
| RARB | retinoic acid receptor, beta | 0.00760007 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0075783 |
| MKI67 | marker of proliferation Ki-67 | 0.00749453 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.00746674 |
| YEATS2 | YEATS domain containing 2 | 0.00744669 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.00736798 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.00724794 |
| LOX | lysyl oxidase | 0.00723054 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.00721537 |
| RAI14 | retinoic acid induced 14 | 0.00717548 |
| TNS1 | tensin 1 | 0.00715956 |
| OSMR | oncostatin M receptor | 0.00715281 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.141856 |
| VIM | vimentin | -0.129649 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0925978 |
| TMSB10 | thymosin beta 10 | -0.0878574 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0770733 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.075113 |
| COL1A2 | collagen, type I, alpha 2 | -0.0651918 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0619581 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0617059 |
| RPS8 | ribosomal protein S8 | -0.0553716 |
| FTL | ferritin, light polypeptide | -0.0535952 |
| PTMA | prothymosin, alpha | -0.05316 |
| MT2A | metallothionein 2A | -0.0498691 |
| RPS6 | ribosomal protein S6 | -0.0488724 |
| RPL35A | ribosomal protein L35a | -0.0463341 |
| CADM1 | cell adhesion molecule 1 | -0.0436737 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0419219 |
| ENO1 | enolase 1, (alpha) | -0.0399638 |
| LDHA | lactate dehydrogenase A | -0.0396308 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0364325 |
| CALR | calreticulin | -0.0364205 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0357235 |
| S100A9 | S100 calcium binding protein A9 | -0.0344155 |
| ACTG1 | actin gamma 1 | -0.0327551 |
| IER3 | immediate early response 3 | -0.0319903 |
| RPL23 | ribosomal protein L23 | -0.0300451 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0300436 |
| PKM | pyruvate kinase, muscle | -0.0295494 |
| MTDH | metadherin | -0.0281025 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.027419 |
| RPLP1 | ribosomal protein, large, P1 | -0.0271595 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0270499 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0268642 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0267809 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0265882 |
| RPL11 | ribosomal protein L11 | -0.0265604 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0256994 |
| S100A6 | S100 calcium binding protein A6 | -0.0250386 |
| UBC | ubiquitin C | -0.0249668 |
| RPL37A | ribosomal protein L37a | -0.0244177 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0241898 |
| DSTN | destrin (actin depolymerizing factor) | -0.0239425 |
| RPL5 | ribosomal protein L5 | -0.0237162 |
| RPS19 | ribosomal protein S19 | -0.0236769 |
| RPL28 | ribosomal protein L28 | -0.0231777 |
| RPL26 | ribosomal protein L26 | -0.0230989 |
| GOLGA4 | golgin A4 | -0.0230032 |
| CANX | calnexin | -0.0227781 |
| RPS3 | ribosomal protein S3 | -0.0225621 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0224413 |
| B2M | beta-2-microglobulin | -0.0222585 |
| SEPTIN7 | septin 7 | -0.0219449 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0214375 |
| RPL8 | ribosomal protein L8 | -0.0212822 |
| RPL19 | ribosomal protein L19 | -0.0211081 |
| LMAN1 | lectin, mannose-binding, 1 | -0.020842 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0207846 |
| RPL30 | ribosomal protein L30 | -0.0206919 |
| RACK1 | receptor for activated C kinase 1 | -0.0206546 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0205706 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0204152 |
| RPLP0 | ribosomal protein, large, P0 | -0.0201617 |
| RPLP2 | ribosomal protein, large, P2 | -0.0201127 |
| RPS13 | ribosomal protein S13 | -0.0200363 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0199722 |
| RPL34 | ribosomal protein L34 | -0.0197973 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0197199 |
| RPS25 | ribosomal protein S25 | -0.0193695 |
| S100A10 | S100 calcium binding protein A10 | -0.0192322 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.019232 |
| HLA-B | major histocompatibility complex, class I, B | -0.0191989 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0190982 |
| RPS12 | ribosomal protein S12 | -0.0188964 |
| RPS11 | ribosomal protein S11 | -0.0187529 |
| FAM162A | family with sequence similarity 162, member A | -0.0187267 |
| TPM2 | tropomyosin 2 (beta) | -0.0186986 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0186723 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0186137 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.018576 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0184828 |
| USP3 | ubiquitin specific peptidase 3 | -0.0182132 |
| RPL12 | ribosomal protein L12 | -0.0180186 |
| TRAM1 | translocation associated membrane protein 1 | -0.0178953 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0176631 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0176327 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0176236 |
| RPS24 | ribosomal protein S24 | -0.0173543 |
| RPL9 | ribosomal protein L9 | -0.017284 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0172815 |
| GNAS | GNAS complex locus | -0.0172229 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0171232 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0169545 |
| RPL36 | ribosomal protein L36 | -0.0169254 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0164164 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.016326 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0160802 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0159238 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0158791 |
| RPL31 | ribosomal protein L31 | -0.0158386 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.015807 |
