| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entrectinib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Entrectinib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0489094 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0470928 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0444127 |
| FOXO1 | forkhead box O1 | 0.0407916 |
| OSMR | oncostatin M receptor | 0.0406322 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0310203 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0304021 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0298223 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0288777 |
| FLNB | filamin B, beta | 0.0273338 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0269058 |
| RIN2 | Ras and Rab interactor 2 | 0.0266747 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0263021 |
| PRELID2 | PRELI domain containing 2 | 0.0259356 |
| EFNA5 | ephrin-A5 | 0.0258881 |
| MTSS1 | metastasis suppressor 1 | 0.0241328 |
| BCL2L1 | BCL2-like 1 | 0.0239926 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0238951 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0237051 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0235303 |
| LUZP1 | leucine zipper protein 1 | 0.0230797 |
| VCL | vinculin | 0.0227784 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0217928 |
| RASAL2 | RAS protein activator like 2 | 0.0214685 |
| LDLR | low density lipoprotein receptor | 0.0213346 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0207006 |
| CAPRIN2 | caprin family member 2 | 0.0196767 |
| SMYD3 | SET and MYND domain containing 3 | 0.0189715 |
| MECOM | MDS1 and EVI1 complex locus | 0.0179852 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0177516 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0173439 |
| RAD51B | RAD51 paralog B | 0.0168938 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0162154 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0161592 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0158161 |
| CDK6 | cyclin-dependent kinase 6 | 0.0158069 |
| FNIP1 | folliculin interacting protein 1 | 0.0156234 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.015574 |
| LAMC2 | laminin, gamma 2 | 0.0154132 |
| SMAD3 | SMAD family member 3 | 0.0151307 |
| FOXP1 | forkhead box P1 | 0.0146226 |
| SETX | senataxin | 0.014555 |
| SEPTIN9 | septin 9 | 0.0145367 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0144966 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0143923 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0142039 |
| BLCAP | bladder cancer associated protein | 0.0141285 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0139242 |
| PLEC | plectin | 0.0138831 |
| EXOC4 | exocyst complex component 4 | 0.0138814 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.013775 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0137392 |
| MCL1 | myeloid cell leukemia 1 | 0.0133727 |
| AOPEP | aminopeptidase O (putative) | 0.013221 |
| IL6ST | interleukin 6 signal transducer | 0.0130981 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0127874 |
| ATM | ATM serine/threonine kinase | 0.012757 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0127002 |
| EXOC6B | exocyst complex component 6B | 0.0125999 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0125638 |
| DUSP4 | dual specificity phosphatase 4 | 0.0125434 |
| EGFR | epidermal growth factor receptor | 0.0124349 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0122877 |
| RAI14 | retinoic acid induced 14 | 0.0121564 |
| FRMD5 | FERM domain containing 5 | 0.0120812 |
| NEK7 | NIMA-related kinase 7 | 0.0120322 |
| KIAA0040 | KIAA0040 | 0.0119578 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0119573 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0119114 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0118578 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0118281 |
| KLF12 | Kruppel-like factor 12 | 0.0118174 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0117117 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0116801 |
| HMGA2 | high mobility group AT-hook 2 | 0.0115597 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0115276 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0115136 |
| METTL15 | methyltransferase like 15 | 0.0113819 |
| TENM4 | teneurin transmembrane protein 4 | 0.0112818 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0112614 |
| ATXN1 | ataxin 1 | 0.0112555 |
| AMOTL1 | angiomotin like 1 | 0.0111769 |
| KIAA1217 | KIAA1217 | 0.0111563 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.01113 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0109809 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0109401 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0109393 |
| CNTNAP3 | contactin associated protein-like 3 | 0.0109206 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0108524 |
| C4BPB | complement component 4 binding protein, beta | 0.0107887 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0106855 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0105587 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0104729 |
| STK10 | serine/threonine kinase 10 | 0.0104092 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0104068 |
| SVIL | supervillin | 0.0103848 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0103607 |
| AHNAK | AHNAK nucleoprotein | 0.0103014 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0103012 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0102298 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180993 |
| NDRG1 | N-myc downstream regulated 1 | -0.151469 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104935 |
| PTMA | prothymosin, alpha | -0.0849556 |
| ENO1 | enolase 1, (alpha) | -0.0765387 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0726826 |
| RPS6 | ribosomal protein S6 | -0.0710292 |
| LDHA | lactate dehydrogenase A | -0.071018 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0695875 |
| MEF2A | myocyte enhancer factor 2A | -0.0687968 |
| PGK1 | phosphoglycerate kinase 1 | -0.065237 |
| S100A10 | S100 calcium binding protein A10 | -0.0639284 |
| RPS8 | ribosomal protein S8 | -0.0620897 |
| B2M | beta-2-microglobulin | -0.060942 |
| ANXA1 | annexin A1 | -0.0591078 |
| TMSB10 | thymosin beta 10 | -0.0589989 |
| MT2A | metallothionein 2A | -0.0532317 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0505604 |
| PKM | pyruvate kinase, muscle | -0.04725 |
| RPS21 | ribosomal protein S21 | -0.0453727 |
| LMNA | lamin A/C | -0.0448299 |
| DSTN | destrin (actin depolymerizing factor) | -0.0447976 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0447886 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427062 |
| GOLGA4 | golgin A4 | -0.0425993 |
| POTEF | POTE ankyrin domain family, member F | -0.0425741 |
| SQLE | squalene epoxidase | -0.0421138 |
| KRT17 | keratin 17, type I | -0.0411539 |
| RPL11 | ribosomal protein L11 | -0.0405054 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0400414 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0394618 |
| CANX | calnexin | -0.0389323 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0384318 |
| GNAS | GNAS complex locus | -0.0384159 |
| YBX1 | Y box binding protein 1 | -0.0374374 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0374136 |
| S100A6 | S100 calcium binding protein A6 | -0.037036 |
| S100A9 | S100 calcium binding protein A9 | -0.0363848 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0362395 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0360774 |
| RPS13 | ribosomal protein S13 | -0.0355795 |
| RPL8 | ribosomal protein L8 | -0.0347681 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0345079 |
| MORF4L2 | mortality factor 4 like 2 | -0.0344436 |
| SPAG9 | sperm associated antigen 9 | -0.0341328 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0338906 |
| STC1 | stanniocalcin 1 | -0.0338114 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0337695 |
| PLS3 | plastin 3 | -0.0333927 |
| RPL23 | ribosomal protein L23 | -0.0331058 |
| RPLP2 | ribosomal protein, large, P2 | -0.0325477 |
| ANXA2 | annexin A2 | -0.0323273 |
| RPS3 | ribosomal protein S3 | -0.0319478 |
| RPS19 | ribosomal protein S19 | -0.0318845 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0314765 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0310089 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0308475 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0307072 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0303657 |
| CALR | calreticulin | -0.0300259 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0299621 |
| TAGLN2 | transgelin 2 | -0.0297635 |
| RPLP0 | ribosomal protein, large, P0 | -0.0291757 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0291477 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0290886 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.029034 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0289243 |
| RPL27A | ribosomal protein L27a | -0.0285221 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0284921 |
| FTL | ferritin, light polypeptide | -0.0283401 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0281897 |
| RPL5 | ribosomal protein L5 | -0.0280659 |
| RACK1 | receptor for activated C kinase 1 | -0.0278928 |
| RPS25 | ribosomal protein S25 | -0.0277279 |
| SRP54 | signal recognition particle 54kDa | -0.0277138 |
| GLYAT | glycine-N-acyltransferase | -0.027709 |
| RPL12 | ribosomal protein L12 | -0.0275762 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0275254 |
| EZR | ezrin | -0.0274419 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0272731 |
| RPL34 | ribosomal protein L34 | -0.0270573 |
| RPL19 | ribosomal protein L19 | -0.0267616 |
| ZNF292 | zinc finger protein 292 | -0.026613 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0264158 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0263156 |
| RPL37 | ribosomal protein L37 | -0.0262036 |
| SEPTIN7 | septin 7 | -0.0261723 |
| S100A2 | S100 calcium binding protein A2 | -0.0261307 |
| RPL35A | ribosomal protein L35a | -0.0260304 |
| MT1X | metallothionein 1X | -0.0259137 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.025646 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0252427 |
| COPA | coatomer protein complex, subunit alpha | -0.0251007 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0250162 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0246237 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0245498 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0243802 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0243583 |
| RPS12 | ribosomal protein S12 | -0.0243493 |
| RPS14 | ribosomal protein S14 | -0.0239365 |
