| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entrectinib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entrectinib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TM4SF1 | transmembrane 4 L six family member 1 | 0.141574 |
| TXNRD1 | thioredoxin reductase 1 | 0.139357 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.131357 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.106504 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0991114 |
| VIM | vimentin | 0.084591 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0708888 |
| RAI1 | retinoic acid induced 1 | 0.0676877 |
| CENPF | centromere protein F, 350/400kDa | 0.065828 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.064335 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0635103 |
| EZR | ezrin | 0.0594835 |
| RTN4 | reticulon 4 | 0.059259 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.058558 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0575234 |
| MKI67 | marker of proliferation Ki-67 | 0.0537571 |
| JUN | jun proto-oncogene | 0.0510076 |
| TMEM41B | transmembrane protein 41B | 0.0496283 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0452822 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0434922 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0415892 |
| FMNL2 | formin-like 2 | 0.0402824 |
| USP34 | ubiquitin specific peptidase 34 | 0.0400233 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0397243 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0395596 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0394372 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0387588 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0374316 |
| JMJD1C | jumonji domain containing 1C | 0.0363189 |
| CAPRIN2 | caprin family member 2 | 0.0358183 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0352969 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.033418 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0333277 |
| FLNB | filamin B, beta | 0.0331938 |
| SPAG9 | sperm associated antigen 9 | 0.0323994 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0322183 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0316758 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0316112 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0312359 |
| PGK1 | phosphoglycerate kinase 1 | 0.0308994 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0308023 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0306862 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.030338 |
| MT1X | metallothionein 1X | 0.0302721 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0300438 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0297228 |
| EGR1 | early growth response 1 | 0.0295926 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0293975 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0292929 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0292784 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0288542 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0288141 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0288053 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0286622 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0275654 |
| CKAP5 | cytoskeleton associated protein 5 | 0.027342 |
| UPP1 | uridine phosphorylase 1 | 0.0272975 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0268719 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0268382 |
| VMP1 | vacuole membrane protein 1 | 0.0268353 |
| FNIP1 | folliculin interacting protein 1 | 0.0266129 |
| RBM25 | RNA binding motif protein 25 | 0.0264219 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0260985 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0258863 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0257515 |
| HPCAL1 | hippocalcin-like 1 | 0.0256848 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0256368 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0254974 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0254961 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0253322 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0253237 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0248944 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0247737 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0245306 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0241916 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0239838 |
| PYGL | phosphorylase, glycogen, liver | 0.0239545 |
| CLTC | clathrin, heavy chain (Hc) | 0.0238144 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0235834 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0235163 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0231525 |
| KLF6 | Kruppel-like factor 6 | 0.0229912 |
| EREG | epiregulin | 0.0229715 |
| YBX3 | Y box binding protein 3 | 0.0229032 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0228585 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0226812 |
| ANLN | anillin, actin binding protein | 0.0225333 |
| NUP58 | nucleoporin 58 | 0.0224949 |
| TPX2 | TPX2, microtubule-associated | 0.0221984 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0220263 |
| CEP170 | centrosomal protein 170kDa | 0.0219135 |
| APP | amyloid beta (A4) precursor protein | 0.0215271 |
| PLK2 | polo-like kinase 2 | 0.0215271 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0214172 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0212555 |
| CDK19 | cyclin-dependent kinase 19 | 0.0212514 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0211819 |
| KIF14 | kinesin family member 14 | 0.0210112 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0209604 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0209432 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143103 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104981 |
| CADM2 | cell adhesion molecule 2 | -0.04454 |
| DST | dystonin | -0.0430484 |
| TXNIP | thioredoxin interacting protein | -0.0418933 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0385678 |
| CALR | calreticulin | -0.0381901 |
| TP63 | tumor protein p63 | -0.036812 |
| RPLP1 | ribosomal protein, large, P1 | -0.0367681 |
| PKM | pyruvate kinase, muscle | -0.0367599 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0358535 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0355516 |
| TMSB10 | thymosin beta 10 | -0.0341993 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0323428 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0321327 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0302715 |
| GOLGA4 | golgin A4 | -0.0296883 |
| FTL | ferritin, light polypeptide | -0.0282066 |
| RPS19 | ribosomal protein S19 | -0.0270365 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.026604 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0249358 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0248342 |
| RPL23 | ribosomal protein L23 | -0.0246737 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0246519 |
| POTEF | POTE ankyrin domain family, member F | -0.0239352 |
| EGFR | epidermal growth factor receptor | -0.0230944 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0222228 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0219083 |
| MT1E | metallothionein 1E | -0.0219082 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0215207 |
| PTMA | prothymosin, alpha | -0.0212015 |
| RPL31 | ribosomal protein L31 | -0.0209388 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0209313 |
| EPHA4 | EPH receptor A4 | -0.0206982 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0206078 |
| TNS3 | tensin 3 | -0.0202279 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0194687 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0193536 |
| RPS8 | ribosomal protein S8 | -0.0190452 |
| RPS12 | ribosomal protein S12 | -0.0188042 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0186883 |
| RPS6 | ribosomal protein S6 | -0.0183964 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0183116 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.018232 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0177737 |
| FNDC3B | fibronectin type III domain containing 3B | -0.017643 |
| RPL28 | ribosomal protein L28 | -0.0176059 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0173779 |
| RPS25 | ribosomal protein S25 | -0.0170752 |
| COL5A2 | collagen, type V, alpha 2 | -0.0169905 |
| LDHA | lactate dehydrogenase A | -0.016927 |
| RPS24 | ribosomal protein S24 | -0.0168906 |
| RPS29 | ribosomal protein S29 | -0.0167783 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0166351 |
| MYOF | myoferlin | -0.0164568 |
| RPL27A | ribosomal protein L27a | -0.0164104 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.016338 |
| RPL37 | ribosomal protein L37 | -0.0160601 |
| PRELID2 | PRELI domain containing 2 | -0.0160593 |
| ASTN2 | astrotactin 2 | -0.0160124 |
| RPL37A | ribosomal protein L37a | -0.0159496 |
| RPS16 | ribosomal protein S16 | -0.0155274 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0155117 |
| CUX1 | cut-like homeobox 1 | -0.0152273 |
| RPS27 | ribosomal protein S27 | -0.0151039 |
| SRP54 | signal recognition particle 54kDa | -0.014904 |
| NDRG1 | N-myc downstream regulated 1 | -0.0148943 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0148352 |
| RPS17 | ribosomal protein S17 | -0.0148242 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.0146863 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0146357 |
| RPL39 | ribosomal protein L39 | -0.0143533 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0139435 |
| PLIN2 | perilipin 2 | -0.0138146 |
| RPL11 | ribosomal protein L11 | -0.0137429 |
| AEBP2 | AE binding protein 2 | -0.0136997 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0135704 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0135585 |
| RPS10 | ribosomal protein S10 | -0.0135199 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0133031 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.013212 |
| B2M | beta-2-microglobulin | -0.01302 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0129687 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0129213 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0128948 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0127903 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0127229 |
| RPL35 | ribosomal protein L35 | -0.012672 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0126344 |
| HLA-A | major histocompatibility complex, class I, A | -0.0126036 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0125715 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0124839 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0124007 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0123191 |
| TRIM56 | tripartite motif containing 56 | -0.0122138 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0121593 |
| RPS28 | ribosomal protein S28 | -0.0120942 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.012054 |
| FTO | fat mass and obesity associated | -0.0120422 |
| RPL38 | ribosomal protein L38 | -0.0120286 |
