| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entrectinib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Entrectinib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0429464 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0356856 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0271588 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0213143 |
| EGFR | epidermal growth factor receptor | 0.018428 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0172143 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0170851 |
| LRRC49 | leucine rich repeat containing 49 | 0.0146842 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0146053 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.014167 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0140284 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0140258 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0140116 |
| ECE1 | endothelin converting enzyme 1 | 0.0135872 |
| CAB39 | calcium binding protein 39 | 0.0132237 |
| CD44 | CD44 molecule (Indian blood group) | 0.0128551 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.011948 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0117817 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0116067 |
| TGM2 | transglutaminase 2 | 0.0112745 |
| VIM | vimentin | 0.011196 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0109481 |
| PRELID2 | PRELI domain containing 2 | 0.010673 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0104654 |
| HDAC9 | histone deacetylase 9 | 0.0104544 |
| FRMD4A | FERM domain containing 4A | 0.0104059 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0103889 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0100895 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0100067 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00976616 |
| MYOF | myoferlin | 0.00970664 |
| CENPF | centromere protein F, 350/400kDa | 0.00969898 |
| NCOA7 | nuclear receptor coactivator 7 | 0.00958513 |
| FAM107B | family with sequence similarity 107, member B | 0.00954519 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00934709 |
| RPL7 | ribosomal protein L7 | 0.00906098 |
| RPL3 | ribosomal protein L3 | 0.00891189 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00877778 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.00871493 |
| FRMD5 | FERM domain containing 5 | 0.00856585 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.00851562 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00829262 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00817839 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.00816191 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00811399 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0080511 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.00800705 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.00787249 |
| RAD51B | RAD51 paralog B | 0.0077033 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00770032 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00756809 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0075176 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00747467 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.00746659 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.00743421 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.00741032 |
| KIAA1328 | KIAA1328 | 0.00739491 |
| SCFD1 | sec1 family domain containing 1 | 0.00722089 |
| FHIT | fragile histidine triad | 0.00720971 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.00718853 |
| TBC1D5 | TBC1 domain family, member 5 | 0.00717453 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0071475 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.00712072 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.00709387 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00688858 |
| PRKCSH | protein kinase C substrate 80K-H | 0.00679614 |
| MSN | moesin | 0.00670901 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00670582 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.00668229 |
| MKI67 | marker of proliferation Ki-67 | 0.00667128 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.00663094 |
| FAM3C | family with sequence similarity 3, member C | 0.00658309 |
| KLF6 | Kruppel-like factor 6 | 0.00658071 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00653702 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0065212 |
| GPR107 | G protein-coupled receptor 107 | 0.00649172 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00642625 |
| KIAA1217 | KIAA1217 | 0.00640616 |
| TCERG1 | transcription elongation regulator 1 | 0.00637059 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | 0.00635813 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.00635196 |
| TLN1 | talin 1 | 0.00630523 |
| IL1R1 | interleukin 1 receptor, type I | 0.00624018 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.00615793 |
| RPL35A | ribosomal protein L35a | 0.0061561 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.00613386 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00612948 |
| TGFB2 | transforming growth factor, beta 2 | 0.00611298 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.00609504 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.00604236 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0060013 |
| TBCK | TBC1 domain containing kinase | 0.0059322 |
| GOLGA3 | golgin A3 | 0.00593118 |
| SON | SON DNA binding protein | 0.00590101 |
| MCL1 | myeloid cell leukemia 1 | 0.00589634 |
| AHI1 | Abelson helper integration site 1 | 0.00588181 |
| PPP1R3B | protein phosphatase 1, regulatory subunit 3B | 0.00587383 |
| RPS23 | ribosomal protein S23 | 0.00584533 |
| CALU | calumenin | 0.00576945 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00570673 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.0896926 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.083705 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0821932 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0707264 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0693779 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0656423 |
| TMSB10 | thymosin beta 10 | -0.0628118 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0586845 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0574987 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.055088 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0483234 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0476899 |
| HMGA2 | high mobility group AT-hook 2 | -0.04467 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0438139 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0436455 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0406432 |
| CDH13 | cadherin 13 | -0.0403634 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.038102 |
| FAM13A | family with sequence similarity 13, member A | -0.037665 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0369244 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0352442 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0346644 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0340965 |
| MTSS1 | metastasis suppressor 1 | -0.0337286 |
| PTMA | prothymosin, alpha | -0.0336233 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0334273 |
| MEF2A | myocyte enhancer factor 2A | -0.0321295 |
| NRG1 | neuregulin 1 | -0.0313292 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0298526 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0296844 |
| CLMP | CXADR-like membrane protein | -0.0295716 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0295512 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.027702 |
| STC1 | stanniocalcin 1 | -0.0270392 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0269416 |
| CDK14 | cyclin-dependent kinase 14 | -0.0266398 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0265233 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0264347 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0263946 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0256593 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0255819 |
| RIOK3 | RIO kinase 3 | -0.0254694 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0250923 |
| S100A6 | S100 calcium binding protein A6 | -0.0249809 |
| PARD3 | par-3 family cell polarity regulator | -0.0246442 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0241138 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0239267 |
| NDRG1 | N-myc downstream regulated 1 | -0.0238004 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0235194 |
| FAM20C | family with sequence similarity 20, member C | -0.0232594 |
| GNAS | GNAS complex locus | -0.0232514 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0229265 |
| PTK2 | protein tyrosine kinase 2 | -0.0227534 |
| USP3 | ubiquitin specific peptidase 3 | -0.0227176 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0225544 |
| HELZ | helicase with zinc finger | -0.022282 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0221943 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0220892 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0220541 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0219558 |
| RBM39 | RNA binding motif protein 39 | -0.0219283 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0218465 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0217221 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0217173 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0215756 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0212472 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0212264 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0210629 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0207838 |
| PKM | pyruvate kinase, muscle | -0.0207394 |
| USP34 | ubiquitin specific peptidase 34 | -0.0207338 |
| CUX1 | cut-like homeobox 1 | -0.0205954 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0205095 |
| FBN1 | fibrillin 1 | -0.0203448 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0201155 |
| LOXL2 | lysyl oxidase-like 2 | -0.0200037 |
| PRKCA | protein kinase C, alpha | -0.0197693 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0196024 |
| ASPH | aspartate beta-hydroxylase | -0.0194898 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0194768 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0193007 |
| PGK1 | phosphoglycerate kinase 1 | -0.019259 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0187077 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0184341 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0182524 |
| GLIS3 | GLIS family zinc finger 3 | -0.0182228 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0182189 |
| IFI44L | interferon-induced protein 44-like | -0.0181228 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0180784 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0179836 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0179321 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0178974 |
| NUMB | numb homolog (Drosophila) | -0.0178696 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0178651 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0178326 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0177886 |
| SEPTIN9 | septin 9 | -0.0177296 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0177278 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0176912 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0176616 |
