| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entrectinib perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Entrectinib_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.127993 |
| POTEF | POTE ankyrin domain family, member F | 0.118899 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.106623 |
| TMSB10 | thymosin beta 10 | 0.0799853 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0729095 |
| KRT7 | keratin 7, type II | 0.0583392 |
| FBXO32 | F-box protein 32 | 0.0542588 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0511219 |
| LAMC2 | laminin, gamma 2 | 0.0499317 |
| CCND1 | cyclin D1 | 0.0470181 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0469705 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0455177 |
| TPM4 | tropomyosin 4 | 0.0397642 |
| HLA-B | major histocompatibility complex, class I, B | 0.0385338 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0374579 |
| ERBIN | erbb2 interacting protein | 0.0371706 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0370872 |
| TPM3 | tropomyosin 3 | 0.0365807 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0356459 |
| VEGFA | vascular endothelial growth factor A | 0.0351888 |
| HLA-A | major histocompatibility complex, class I, A | 0.0349434 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0349246 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.034375 |
| MCU | mitochondrial calcium uniporter | 0.0337411 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0337 |
| RBM25 | RNA binding motif protein 25 | 0.0335141 |
| VCL | vinculin | 0.0332056 |
| PTMA | prothymosin, alpha | 0.0329359 |
| LAMB3 | laminin, beta 3 | 0.0328905 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0322124 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0318769 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0317764 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0316811 |
| TMSB4X | thymosin beta 4, X-linked | 0.0311804 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0303672 |
| MAP1B | microtubule-associated protein 1B | 0.0297901 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0296814 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0292439 |
| FNIP1 | folliculin interacting protein 1 | 0.0289731 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0283655 |
| RCOR1 | REST corepressor 1 | 0.0282949 |
| MYO1E | myosin IE | 0.0279862 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0276755 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0273741 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0263152 |
| KRT8 | keratin 8, type II | 0.0259714 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0259417 |
| FLNA | filamin A, alpha | 0.0253013 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.024633 |
| NF1 | neurofibromin 1 | 0.0244338 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0243846 |
| LMNA | lamin A/C | 0.0243677 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0241612 |
| SFTPA2 | surfactant protein A2 | 0.0238322 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0238228 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0236932 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0234261 |
| CLTC | clathrin, heavy chain (Hc) | 0.0233585 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0232479 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0232354 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0231255 |
| TMEM165 | transmembrane protein 165 | 0.0226371 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0224578 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.022412 |
| ZNF148 | zinc finger protein 148 | 0.022066 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0220442 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0218869 |
| ETV6 | ets variant 6 | 0.0217241 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0216726 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0216042 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0214445 |
| USP53 | ubiquitin specific peptidase 53 | 0.0211931 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0211319 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0210363 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0207786 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0206383 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0205906 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0205679 |
| TMF1 | TATA element modulatory factor 1 | 0.0205194 |
| EPCAM | epithelial cell adhesion molecule | 0.0204571 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0204391 |
| TUFT1 | tuftelin 1 | 0.0202849 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0202171 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0202003 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0199806 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0199207 |
| PLEC | plectin | 0.0198767 |
| FBXO34 | F-box protein 34 | 0.0197951 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0197777 |
| COPA | coatomer protein complex, subunit alpha | 0.0196984 |
| GOLM1 | golgi membrane protein 1 | 0.0196151 |
| GOLGA4 | golgin A4 | 0.0195404 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0194754 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0194201 |
| FNBP4 | formin binding protein 4 | 0.0194201 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.0193721 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0193221 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0192445 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.019211 |
| SRPK2 | SRSF protein kinase 2 | 0.0190421 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.231622 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175274 |
| NDRG1 | N-myc downstream regulated 1 | -0.171902 |
| FTL | ferritin, light polypeptide | -0.128891 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0806285 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0739018 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0671907 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0616455 |
| MT2A | metallothionein 2A | -0.0595837 |
| HMGA1 | high mobility group AT-hook 1 | -0.0570781 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0461341 |
| G0S2 | G0/G1 switch 2 | -0.0450348 |
| ASPH | aspartate beta-hydroxylase | -0.0421448 |
| TOP1 | topoisomerase (DNA) I | -0.0401039 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0391848 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0362605 |
| FOSL1 | FOS-like antigen 1 | -0.0355787 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0355607 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0349567 |
| RPLP0 | ribosomal protein, large, P0 | -0.0345073 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0340232 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0329755 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0324547 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0324367 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0319208 |
| S100A10 | S100 calcium binding protein A10 | -0.030295 |
| USP3 | ubiquitin specific peptidase 3 | -0.0298847 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0289538 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0273148 |
| RNF145 | ring finger protein 145 | -0.0269145 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0263778 |
| FHIT | fragile histidine triad | -0.0261101 |
| FAM162A | family with sequence similarity 162, member A | -0.0259331 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0257858 |
| RPS6 | ribosomal protein S6 | -0.0248723 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0244595 |
| NAV2 | neuron navigator 2 | -0.0242638 |
| S100A6 | S100 calcium binding protein A6 | -0.0241742 |
| RPS27 | ribosomal protein S27 | -0.023404 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0233729 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0233562 |
| LDHA | lactate dehydrogenase A | -0.0233459 |
| RPS8 | ribosomal protein S8 | -0.0225345 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0210786 |
| CCNI | cyclin I | -0.0209853 |
| CCNB1 | cyclin B1 | -0.0198522 |
| RYBP | RING1 and YY1 binding protein | -0.0195173 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0193906 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0192149 |
| SMC4 | structural maintenance of chromosomes 4 | -0.018926 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0188782 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0188277 |
| KIAA1217 | KIAA1217 | -0.0188137 |
| YBX1 | Y box binding protein 1 | -0.0186584 |
| CENPE | centromere protein E, 312kDa | -0.0186362 |
| RPLP1 | ribosomal protein, large, P1 | -0.0186105 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0184538 |
| RPS19 | ribosomal protein S19 | -0.0184385 |
| DUSP6 | dual specificity phosphatase 6 | -0.018431 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0184062 |
| ARRDC3 | arrestin domain containing 3 | -0.0182398 |
| FAM13A | family with sequence similarity 13, member A | -0.0182215 |
| ENO1 | enolase 1, (alpha) | -0.0182154 |
| EMP1 | epithelial membrane protein 1 | -0.0181614 |
| CENPF | centromere protein F, 350/400kDa | -0.0180797 |
| QKI | QKI, KH domain containing, RNA binding | -0.0177412 |
| CHMP2B | charged multivesicular body protein 2B | -0.0176966 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0175921 |
| CPNE3 | copine III | -0.0173914 |
| ACTG1 | actin gamma 1 | -0.0173608 |
| ECT2 | epithelial cell transforming 2 | -0.0173199 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0172938 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0171697 |
| COX7C | cytochrome c oxidase subunit VIIc | -0.0170827 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0169829 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.016741 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0167317 |
| TXNRD1 | thioredoxin reductase 1 | -0.0167231 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0167098 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0167045 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0166905 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0166824 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0165485 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0164485 |
| MKI67 | marker of proliferation Ki-67 | -0.0163315 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0161123 |
| RPL21 | ribosomal protein L21 | -0.01576 |
| EHF | ets homologous factor | -0.0155984 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0155418 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0154541 |
| RTN4 | reticulon 4 | -0.0153406 |
| PCBP2 | poly(rC) binding protein 2 | -0.0151449 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0151366 |
| RPL19 | ribosomal protein L19 | -0.0151081 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0151063 |
| NUP58 | nucleoporin 58 | -0.0150663 |
| SQLE | squalene epoxidase | -0.014968 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0148476 |
| AREG | amphiregulin | -0.0146254 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0145766 |
