| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entrectinib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
126 genes differentially expressed following the Entrectinib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SBF2 | SET binding factor 2 | 0.0838458 |
| FN1 | fibronectin 1 | 0.0766384 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0742 |
| ATP13A3 | ATPase type 13A3 | 0.0660671 |
| COL5A2 | collagen, type V, alpha 2 | 0.0655795 |
| PKM | pyruvate kinase, muscle | 0.0581224 |
| TENM3 | teneurin transmembrane protein 3 | 0.0569626 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.053594 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0534922 |
| FMNL2 | formin-like 2 | 0.0514031 |
| RIGI | RNA sensor RIG-I | 0.0498912 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0497679 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0479908 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0478364 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0476833 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0457146 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0456812 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0452366 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0445987 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0411683 |
| JMJD1C | jumonji domain containing 1C | 0.0408713 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0393535 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0392741 |
| ANO6 | anoctamin 6 | 0.0384138 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0378185 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0377361 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0361976 |
| SMYD3 | SET and MYND domain containing 3 | 0.0345599 |
| CNKSR3 | CNKSR family member 3 | 0.032571 |
| FTL | ferritin, light polypeptide | 0.0323226 |
| NAV2 | neuron navigator 2 | 0.0303733 |
| STC1 | stanniocalcin 1 | 0.0300387 |
| BBX | bobby sox homolog (Drosophila) | 0.0300184 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0295233 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0292951 |
| B2M | beta-2-microglobulin | 0.0288038 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0258978 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0257392 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0253669 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0253385 |
| DST | dystonin | 0.0251275 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0245019 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0241046 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0238941 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0238456 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0179669 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0176902 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0151305 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0148329 |
| GPC6 | glypican 6 | 0.013472 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0134141 |
| SPAG9 | sperm associated antigen 9 | 0.0126383 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0123996 |
| MT2A | metallothionein 2A | 0.0112944 |
| RBM39 | RNA binding motif protein 39 | 0.0100156 |
| RAB1A | RAB1A, member RAS oncogene family | 0.00984957 |
| LMO7 | LIM domain 7 | 0.00913333 |
| OGA | O-GlcNAcase | 0.0077789 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00757351 |
| RUNX1 | runt-related transcription factor 1 | 0.00593226 |
| IGF2 | insulin-like growth factor 2 | 0.00386417 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0026905 |
| DSCAM | Down syndrome cell adhesion molecule | 0.00223616 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.254275 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.108514 |
| TMSB10 | thymosin beta 10 | -0.104681 |
| EFNA5 | ephrin-A5 | -0.0976881 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.09074 |
| MYO1E | myosin IE | -0.0872337 |
| VIM | vimentin | -0.0846364 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0716457 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0709325 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0619096 |
| NDRG1 | N-myc downstream regulated 1 | -0.0608421 |
| CANX | calnexin | -0.0586549 |
| HMGA2 | high mobility group AT-hook 2 | -0.052115 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0466912 |
| PTMA | prothymosin, alpha | -0.0441578 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0435051 |
| PRKCA | protein kinase C, alpha | -0.0429508 |
| COL5A1 | collagen, type V, alpha 1 | -0.0429168 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0428483 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0428097 |
| FLNB | filamin B, beta | -0.0415448 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0412536 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0403446 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0384083 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0347396 |
| CDH13 | cadherin 13 | -0.0345887 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0343399 |
| RPS6 | ribosomal protein S6 | -0.0339466 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0318827 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0315999 |
| RPS19 | ribosomal protein S19 | -0.0278965 |
| MYOF | myoferlin | -0.0266499 |
| RPS25 | ribosomal protein S25 | -0.0249865 |
| ASPH | aspartate beta-hydroxylase | -0.0244851 |
| PTK2 | protein tyrosine kinase 2 | -0.0225416 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.021051 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0208766 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0205574 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0185114 |
| RPL23 | ribosomal protein L23 | -0.0183939 |
| RPS8 | ribosomal protein S8 | -0.0175226 |
| ANXA2 | annexin A2 | -0.0170693 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0164827 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0161179 |
| PARD3 | par-3 family cell polarity regulator | -0.0152714 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0148589 |
| LDHA | lactate dehydrogenase A | -0.0147287 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0137966 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0134034 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0131609 |
| PDE10A | phosphodiesterase 10A | -0.0125163 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.012439 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0117838 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0109984 |
| RPS12 | ribosomal protein S12 | -0.00973353 |
| VCL | vinculin | -0.00774401 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.00578817 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0054264 |
| TPM4 | tropomyosin 4 | -0.0033833 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00294161 |
| MCL1 | myeloid cell leukemia 1 | -0.00242571 |
| RNF213 | ring finger protein 213 | -0.00172705 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00141007 |
