| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Entrectinib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Entrectinib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.113275 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0855829 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0644877 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0602375 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0599121 |
| OSMR | oncostatin M receptor | 0.0501105 |
| TMEM156 | transmembrane protein 156 | 0.0495071 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0490674 |
| SMOX | spermine oxidase | 0.0386344 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0373353 |
| TPR | translocated promoter region, nuclear basket protein | 0.0366659 |
| PELO | pelota homolog (Drosophila) | 0.0352848 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0347515 |
| EREG | epiregulin | 0.0320486 |
| IL6ST | interleukin 6 signal transducer | 0.0313346 |
| NRP1 | neuropilin 1 | 0.0308273 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0299797 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0281128 |
| WDR26 | WD repeat domain 26 | 0.0278838 |
| EXT1 | exostosin glycosyltransferase 1 | 0.025406 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0253639 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0249666 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0240856 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0229404 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0225425 |
| RUNX2 | runt-related transcription factor 2 | 0.0222338 |
| ITGA1 | integrin, alpha 1 | 0.0221054 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0219871 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0214286 |
| CAB39 | calcium binding protein 39 | 0.0200079 |
| CD44 | CD44 molecule (Indian blood group) | 0.0189086 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0187961 |
| HOMER2 | homer scaffolding protein 2 | 0.018705 |
| SMAD3 | SMAD family member 3 | 0.0186363 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0184489 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.017925 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0176764 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0176311 |
| VMP1 | vacuole membrane protein 1 | 0.0174327 |
| ENAH | enabled homolog (Drosophila) | 0.0172635 |
| RAB31 | RAB31, member RAS oncogene family | 0.0172434 |
| TGM2 | transglutaminase 2 | 0.0167847 |
| AHR | aryl hydrocarbon receptor | 0.0166086 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.015941 |
| RNF24 | ring finger protein 24 | 0.0157983 |
| DUSP5 | dual specificity phosphatase 5 | 0.0157105 |
| FAM20C | family with sequence similarity 20, member C | 0.015699 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0156901 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.015664 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0156612 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0154806 |
| KSR1 | kinase suppressor of ras 1 | 0.0153571 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0152369 |
| STK24 | serine/threonine kinase 24 | 0.0150967 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0150866 |
| OGA | O-GlcNAcase | 0.0149871 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0149522 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0149479 |
| WASL | Wiskott-Aldrich syndrome-like | 0.014926 |
| NUP58 | nucleoporin 58 | 0.014878 |
| PNN | pinin, desmosome associated protein | 0.0146239 |
| ATP11A | ATPase, class VI, type 11A | 0.0145021 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0144912 |
| CENPF | centromere protein F, 350/400kDa | 0.0141006 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0140529 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0140304 |
| CUL3 | cullin 3 | 0.0138877 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0137396 |
| RBM25 | RNA binding motif protein 25 | 0.0135649 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0135506 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0133751 |
| TBK1 | TANK-binding kinase 1 | 0.0133747 |
| IPMK | inositol polyphosphate multikinase | 0.0132744 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.013107 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0130289 |
| SUCO | SUN domain containing ossification factor | 0.0129782 |
| SSH1 | slingshot protein phosphatase 1 | 0.0129045 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0127287 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0126418 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0126351 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0124567 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0123503 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0122305 |
| MSN | moesin | 0.0121894 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.0121334 |
| RBM39 | RNA binding motif protein 39 | 0.0120759 |
| TXNRD1 | thioredoxin reductase 1 | 0.0120361 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0120329 |
| FLNA | filamin A, alpha | 0.0119783 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0119658 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0118827 |
| SF1 | splicing factor 1 | 0.0118584 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0118418 |
| THOC2 | THO complex 2 | 0.0118377 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0117287 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0115447 |
| USP15 | ubiquitin specific peptidase 15 | 0.0115071 |
| FBXO28 | F-box protein 28 | 0.0114391 |
| CEP192 | centrosomal protein 192kDa | 0.0113721 |
| OTUD7B | OTU deubiquitinase 7B | 0.0112638 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.23342 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.191213 |
| FN1 | fibronectin 1 | -0.180385 |
| NRG1 | neuregulin 1 | -0.153449 |
| PTMA | prothymosin, alpha | -0.123765 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0972974 |
| TMSB10 | thymosin beta 10 | -0.0749369 |
| NDRG1 | N-myc downstream regulated 1 | -0.07306 |
| ASPH | aspartate beta-hydroxylase | -0.0713782 |
| HMGA2 | high mobility group AT-hook 2 | -0.066856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0644538 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.059225 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.058603 |
| S100A6 | S100 calcium binding protein A6 | -0.0563062 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0561558 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0557296 |
| VIM | vimentin | -0.0550101 |
| CANX | calnexin | -0.054698 |
| SQSTM1 | sequestosome 1 | -0.052839 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0520468 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0514905 |
| STC2 | stanniocalcin 2 | -0.0510606 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0483765 |
| RPL26 | ribosomal protein L26 | -0.0473856 |
| RACK1 | receptor for activated C kinase 1 | -0.04599 |
| HLA-B | major histocompatibility complex, class I, B | -0.0449735 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0432589 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0429192 |
| FTL | ferritin, light polypeptide | -0.0422991 |
| ENO1 | enolase 1, (alpha) | -0.0416269 |
| RPS12 | ribosomal protein S12 | -0.0415063 |
| RPL37A | ribosomal protein L37a | -0.0410565 |
| RPS6 | ribosomal protein S6 | -0.0407249 |
| PKM | pyruvate kinase, muscle | -0.0396501 |
| CADM1 | cell adhesion molecule 1 | -0.03934 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0392286 |
| PLIN2 | perilipin 2 | -0.0388375 |
| RPL31 | ribosomal protein L31 | -0.0385132 |
| RPS8 | ribosomal protein S8 | -0.0377641 |
| FAM13A | family with sequence similarity 13, member A | -0.0369197 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0359486 |
| SFTPA2 | surfactant protein A2 | -0.0357277 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0356813 |
| RPS27 | ribosomal protein S27 | -0.0356061 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0355901 |
| B2M | beta-2-microglobulin | -0.0354308 |
| RPS24 | ribosomal protein S24 | -0.0353588 |
| INTS6 | integrator complex subunit 6 | -0.0346185 |
| CALR | calreticulin | -0.0340465 |
| RPLP1 | ribosomal protein, large, P1 | -0.0337512 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.03359 |
| S100A10 | S100 calcium binding protein A10 | -0.033488 |
| RPL35A | ribosomal protein L35a | -0.0333728 |
| ACTG1 | actin gamma 1 | -0.0331915 |
| RPL12 | ribosomal protein L12 | -0.0322822 |
| AEBP2 | AE binding protein 2 | -0.031965 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0318492 |
| TMSB4X | thymosin beta 4, X-linked | -0.0310568 |
| RPS29 | ribosomal protein S29 | -0.0308414 |
| RAI14 | retinoic acid induced 14 | -0.0304317 |
| RPS19 | ribosomal protein S19 | -0.0303251 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0302238 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0301244 |
| RPS20 | ribosomal protein S20 | -0.0300803 |
| RPS3 | ribosomal protein S3 | -0.0300054 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0297398 |
| LMNA | lamin A/C | -0.0294962 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0289924 |
| RPL37 | ribosomal protein L37 | -0.0287399 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0282762 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0282151 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0277618 |
| RPS25 | ribosomal protein S25 | -0.0276314 |
| TXNIP | thioredoxin interacting protein | -0.0276204 |
| RPL34 | ribosomal protein L34 | -0.0270101 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0269641 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0269042 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0267972 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.026653 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0265276 |
| RPL28 | ribosomal protein L28 | -0.0263226 |
| RPS27A | ribosomal protein S27a | -0.0260909 |
| RPL23 | ribosomal protein L23 | -0.0260411 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0258878 |
| GPC6 | glypican 6 | -0.0257001 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0256313 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0255363 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0246057 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0242205 |
| RPL19 | ribosomal protein L19 | -0.024044 |
| MYOF | myoferlin | -0.023977 |
| GNAS | GNAS complex locus | -0.0239565 |
| RPL11 | ribosomal protein L11 | -0.0237788 |
| RPL38 | ribosomal protein L38 | -0.0236533 |
| LRRC23 | leucine rich repeat containing 23 | -0.0236293 |
| RPS5 | ribosomal protein S5 | -0.0236173 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0228402 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0227548 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0225918 |
| ASTN2 | astrotactin 2 | -0.0224812 |
