Epilepsy, Tonic-Clonic Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D004830
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Genes

578 genes/proteins associated with the disease Epilepsy, Tonic-Clonic from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
BDNF brain-derived neurotrophic factor 2.88009
POMC proopiomelanocortin 2.88009
NES nestin 2.88009
BCHE butyrylcholinesterase 2.88009
NTF3 neurotrophin 3 2.88009
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.88009
NGF nerve growth factor (beta polypeptide) 2.88009
HBEGF heparin-binding EGF-like growth factor 2.88009
FGF2 fibroblast growth factor 2 (basic) 2.88009
OXT oxytocin/neurophysin I prepropeptide 2.88009
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.41243
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.4079
TNF tumor necrosis factor 2.33893
FOS FBJ murine osteosarcoma viral oncogene homolog 2.32834
CAT catalase 2.32202
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.31599
MAPK1 mitogen-activated protein kinase 1 2.30262
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.2874
MAPK3 mitogen-activated protein kinase 3 2.26595
BAX BCL2-associated X protein 2.21917
BCL2 B-cell CLL/lymphoma 2 2.17317
NOS2 nitric oxide synthase 2, inducible 2.16121
JUN jun proto-oncogene 2.1336
IL6 interleukin 6 2.08344
PRL prolactin 2.0725
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.06513
EGR1 early growth response 1 1.99567
GSTP1 glutathione S-transferase pi 1 1.97813
MAPK8 mitogen-activated protein kinase 8 1.97728
CXCL8 chemokine (C-X-C motif) ligand 8 1.97449
NPY neuropeptide Y 1.96891
DRD1 dopamine receptor D1 1.96506
DRD2 dopamine receptor D2 1.96328
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.9557
IL1B interleukin 1, beta 1.93414
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.92058
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.90935
GFAP glial fibrillary acidic protein 1.90853
DUSP1 dual specificity phosphatase 1 1.88852
FAS Fas cell surface death receptor 1.8877
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.88092
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.87742
SOD2 superoxide dismutase 2, mitochondrial 1.8634
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.86253
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.86184
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.86132
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.85134
OPRM1 opioid receptor, mu 1 1.83361
MAOA monoamine oxidase A 1.82954
TP53 tumor protein p53 1.8152
CREB1 cAMP responsive element binding protein 1 1.81465
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.7853
IFNG interferon, gamma 1.77179
VEGFA vascular endothelial growth factor A 1.76849
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.7652
HMOX1 heme oxygenase 1 1.7619
IL2 interleukin 2 1.75934
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.75003
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.74862
NUPR1 nuclear protein, transcriptional regulator, 1 1.74621
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.7448
TH tyrosine hydroxylase 1.7446
TAC1 tachykinin, precursor 1 1.74321
PRKCE protein kinase C, epsilon 1.72405
ADORA2A adenosine A2a receptor 1.71544
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.7107
ACHE acetylcholinesterase (Yt blood group) 1.70347
FABP1 fatty acid binding protein 1, liver 1.70306
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.69867
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.69405
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.68464
CALCA calcitonin-related polypeptide alpha 1.66382
CES2 carboxylesterase 2 1.65643
GSTM1 glutathione S-transferase mu 1 1.65533
GSK3B glycogen synthase kinase 3 beta 1.65402
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.65271
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.65
JUNB jun B proto-oncogene 1.64303
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.63899
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.62893
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.6287
IL1A interleukin 1, alpha 1.62825
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.62579
ICAM1 intercellular adhesion molecule 1 1.62468
EDN1 endothelin 1 1.61621
CRH corticotropin releasing hormone 1.61061
NOS1 nitric oxide synthase 1 (neuronal) 1.6036
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.60314
ARC activity-regulated cytoskeleton-associated protein 1.59614
C10ORF10 chromosome 10 open reading frame 10 1.59218
TAGLN transgelin 1.59172
BCL2L1 BCL2-like 1 1.58065
ADORA1 adenosine A1 receptor 1.57571
INHBE inhibin, beta E 1.57257
PARP1 poly (ADP-ribose) polymerase 1 1.56361
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.56166
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.56141
TGFB1 transforming growth factor, beta 1 1.56068
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.55747
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.55157
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.55133
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.54523
PENK proenkephalin 1.54499
MAOB monoamine oxidase B 1.54499
MAPK14 mitogen-activated protein kinase 14 1.54232
NEFH neurofilament, heavy polypeptide 1.53184
PDE4B phosphodiesterase 4B, cAMP-specific 1.53184
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.52111
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.51886
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.51355
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.51004
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.51004
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.50903
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.50852
HSPA1A heat shock 70kDa protein 1A 1.50725
SOD1 superoxide dismutase 1, soluble 1.5065
IL4 interleukin 4 1.50095
GRM1 glutamate receptor, metabotropic 1 1.50018
GAL galanin/GMAP prepropeptide 1.49992
IL10 interleukin 10 1.49711
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.49558
CNR1 cannabinoid receptor 1 (brain) 1.48967
CTSL cathepsin L 1.48916
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.48633
CCL2 chemokine (C-C motif) ligand 2 1.48556
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.47711
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.47348
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.46754
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.46409
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 1.46409
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.45962
NUCLEOLIN nucleolin multifunctional protein 1.45115
HOMER1 homer scaffolding protein 1 1.45115
DDIT3 DNA-damage-inducible transcript 3 1.44599
SREBF1 sterol regulatory element binding transcription factor 1 1.44544
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.44544
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.443
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.44273
CCND1 cyclin D1 1.44029
RB1 retinoblastoma 1 1.43455
OPRK1 opioid receptor, kappa 1 1.43428
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.42994
REN renin 1.42616
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.42129
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.42129
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 1.42047
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.41938
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.41368
LHB luteinizing hormone beta polypeptide 1.41146
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.41091
CXCL2 chemokine (C-X-C motif) ligand 2 1.40623
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.40513
FNDC4 fibronectin type III domain containing 4 1.40513
GRIK5 glutamate receptor, ionotropic, kainate 5 1.40513
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 1.40064
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.39366
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.39142
GRIK2 glutamate receptor, ionotropic, kainate 2 1.3903
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.38946
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.38835
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.38584
CES1 carboxylesterase 1 1.38555
TXNRD1 thioredoxin reductase 1 1.38242
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.37874
CDK2 cyclin-dependent kinase 2 1.37789
AVP arginine vasopressin 1.37733
DRD4 dopamine receptor D4 1.37619
EGR2 early growth response 2 1.37475
MAPT microtubule-associated protein tau 1.37475
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.37189
TLR4 toll-like receptor 4 1.36961
FOSL2 FOS-like antigen 2 1.36848
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.36504
PTK2B protein tyrosine kinase 2 beta 1.36504
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.36304
VIM vimentin 1.36275
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.36275
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.36247
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.36047
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.35792
PER2 period circadian clock 2 1.35502
CALR calreticulin 1.35415
CTSD cathepsin D 1.35386
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.35357
ERN1 endoplasmic reticulum to nucleus signaling 1 1.35184
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.35184
RGS2 regulator of G-protein signaling 2 1.34897
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.34869
TEX261 testis expressed 261 1.3484
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.34782
GPX1 glutathione peroxidase 1 1.34635
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.34489
PRKCB protein kinase C, beta 1.34401
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.33612
TPI1 triosephosphate isomerase 1 1.33583
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.33199
SREBF2 sterol regulatory element binding transcription factor 2 1.32369
EFNB1 ephrin-B1 1.31985
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 1.31746
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.31686
NFE2L2 nuclear factor, erythroid 2-like 2 1.31327
IL2RA interleukin 2 receptor, alpha 1.31178
CCNB2 cyclin B2 1.31059
GRIK1 glutamate receptor, ionotropic, kainate 1 1.30269
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.30269
EDNRB endothelin receptor type B 1.30147
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 1.29996
HSPA1B heat shock 70kDa protein 1B 1.29905
RPA2 replication protein A2, 32kDa 1.2975
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.29688
IGF1 insulin-like growth factor 1 (somatomedin C) 1.2895
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.28765
HSPA8 heat shock 70kDa protein 8 1.28703
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.28672
HPN hepsin 1.28672
ACIN1 apoptotic chromatin condensation inducer 1 1.28579
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.28549
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.28456
SELL selectin L 1.28456
MMP13 matrix metallopeptidase 13 1.28364
PRLR prolactin receptor 1.28272
CDK5 cyclin-dependent kinase 5 1.28149
DLAT dihydrolipoamide S-acetyltransferase 1.28149
RGS4 regulator of G-protein signaling 4 1.28088
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.27782
TKT transketolase 1.27751
PLAT plasminogen activator, tissue 1.27657
GLDC glycine dehydrogenase (decarboxylating) 1.27626
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.27533
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.27471
CTSB cathepsin B 1.27286
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.27132
GSTM3 glutathione S-transferase mu 3 (brain) 1.2707
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 1.26638
NPPA natriuretic peptide A 1.26452
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.26421
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.25682
MCL1 myeloid cell leukemia 1 1.25619
INS insulin 1.25588
CYCS cytochrome c, somatic 1.25028
PLCD1 phospholipase C, delta 1 1.24843
LDHB lactate dehydrogenase B 1.24307
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.24087
SIGMAR1 sigma non-opioid intracellular receptor 1 1.23962
GSR glutathione reductase 1.23868
ACSL5 acyl-CoA synthetase long-chain family member 5 1.23837
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.23837
PRKCD protein kinase C, delta 1.23806
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.23743
GLUL glutamate-ammonia ligase 1.23616
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.23616
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.2352
S100A8 S100 calcium binding protein A8 1.2336
S100B S100 calcium binding protein B 1.23328
ADRB1 adrenoceptor beta 1 1.22371
POR P450 (cytochrome) oxidoreductase 1.22209
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.22177
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.21663
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.21631
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.21631
PHB prohibitin 1.21435
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.21271
MAP2K2 mitogen-activated protein kinase kinase 2 1.21206
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.21206
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.21173
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.20946
CLTB clathrin, light chain B 1.20913
MAPK9 mitogen-activated protein kinase 9 1.20654
RELN reelin 1.20361
MEX3B mex-3 RNA binding family member B 1.20295
COX6C cytochrome c oxidase subunit VIc 1.20295
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.20262
CCND3 cyclin D3 1.20031
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.19933
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.19835
ATF7 activating transcription factor 7 1.19704
SYN2 synapsin II 1.19672
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.19639
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.19639
CREM cAMP responsive element modulator 1.19639
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.19345
GCLM glutamate-cysteine ligase, modifier subunit 1.19279
PF4 platelet factor 4 1.19146
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.19146
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.19113
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.18751
BAK1 BCL2-antagonist/killer 1 1.18685
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.18521
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 1.18521
HRH1 histamine receptor H1 1.18456
TRH thyrotropin-releasing hormone 1.18359
AR androgen receptor 1.18026
EGR3 early growth response 3 1.17993
FZD4 frizzled class receptor 4 1.17959
GLS2 glutaminase 2 (liver, mitochondrial) 1.17959
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.17629
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.17629
SGK1 serum/glucocorticoid regulated kinase 1 1.17596
GPR88 G protein-coupled receptor 88 1.17235
CHDH choline dehydrogenase 1.17235
STX12 syntaxin 12 1.17235
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.17235
SOCS6 suppressor of cytokine signaling 6 1.17235
EGFR epidermal growth factor receptor 1.17101
INSR insulin receptor 1.17067
PGK1 phosphoglycerate kinase 1 1.17067
FANCG Fanconi anemia, complementation group G 1.16833
E2F1 E2F transcription factor 1 1.16733
FGFR1 fibroblast growth factor receptor 1 1.16533
PER1 period circadian clock 1 1.16467
LBP lipopolysaccharide binding protein 1.16467
NREP neuronal regeneration related protein 1.16467
SYT4 synaptotagmin IV 1.16368
MAP2K5 mitogen-activated protein kinase kinase 5 1.16302
IGFBP1 insulin-like growth factor binding protein 1 1.16302
OPRL1 opiate receptor-like 1 1.16302
ALAS1 5'-aminolevulinate synthase 1 1.16269
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.16104
GNAS GNAS complex locus 1.16001
ATF4 activating transcription factor 4 1.15899
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.15763
CTH cystathionine gamma-lyase 1.15729
TRHR thyrotropin-releasing hormone receptor 1.15526
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.15492
TFRC transferrin receptor 1.15458
BMP4 bone morphogenetic protein 4 1.15458
ALAD aminolevulinate dehydratase 1.15458
CCNF cyclin F 1.15391
POU2F1 POU class 2 homeobox 1 1.15256
MAP3K7 mitogen-activated protein kinase kinase kinase 7 1.15256
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.15189
CCL5 chemokine (C-C motif) ligand 5 1.15156
APP amyloid beta (A4) precursor protein 1.15055
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.15022
UBC ubiquitin C 1.15022
EIF1 eukaryotic translation initiation factor 1 1.14747
EFNB3 ephrin-B3 1.14713
PLCD4 phospholipase C, delta 4 1.14713
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 1.14678
CRTC3 CREB regulated transcription coactivator 3 1.1461
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.14438
TJP1 tight junction protein 1 1.14404
DES desmin 1.14336
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 1.14234
CCNL1 cyclin L1 1.14234
INHA inhibin, alpha 1.14234
S100A9 S100 calcium binding protein A9 1.14132
SLC19A1 solute carrier family 19 (folate transporter), member 1 1.13963
DCAF8 DDB1 and CUL4 associated factor 8 1.13895
LARGE like-glycosyltransferase 1.13895
EFNA5 ephrin-A5 1.13895
GNS glucosamine (N-acetyl)-6-sulfatase 1.13862
FOSL1 FOS-like antigen 1 1.13862
STAR steroidogenic acute regulatory protein 1.13827
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.13689
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.13655
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.13655
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.13621
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.13449
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 1.13245
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 1.13245
DPYSL2 dihydropyrimidinase-like 2 1.13245
FANCM Fanconi anemia, complementation group M 1.13143
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.13143
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.13109
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 1.13075
SBNO1 strawberry notch homolog 1 (Drosophila) 1.13075
CCK cholecystokinin 1.12973
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.12771
ALDOC aldolase C, fructose-bisphosphate 1.12634
MMP9 matrix metallopeptidase 9 1.12564
LPL lipoprotein lipase 1.12564
HSPB1 heat shock 27kDa protein 1 1.12391
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 1.12357
BRWD1 bromodomain and WD repeat domain containing 1 1.12323
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.12288
AXIN2 axin 2 1.12288
PVALB parvalbumin 1.12288
ALB albumin 1.12151
EZR ezrin 1.1198
BHMT betaine--homocysteine S-methyltransferase 1.1198
F2 coagulation factor II (thrombin) 1.11911
IHH indian hedgehog 1.11843
GLRA2 glycine receptor, alpha 2 1.11809
CA2 carbonic anhydrase II 1.11673
STMN1 stathmin 1 1.11673
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 1.11606
COBL cordon-bleu WH2 repeat protein 1.11606
SMC2 structural maintenance of chromosomes 2 1.1136
CHKA choline kinase alpha 1.1136
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.1136
CCNE1 cyclin E1 1.11186
MPO myeloperoxidase 1.11116
PKLR pyruvate kinase, liver and RBC 1.11011
BBC3 BCL2 binding component 3 1.10942
PTGIS prostaglandin I2 (prostacyclin) synthase 1.10907
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.10907
TUBA4A tubulin, alpha 4a 1.10907
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.10907
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.10872
CUL4A cullin 4A 1.10872
NQO1 NAD(P)H dehydrogenase, quinone 1 1.10872
CTPS2 CTP synthase 2 1.10872
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.10699
GUSB glucuronidase, beta 1.10699
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.10596
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.10459
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.10459
GADD45A growth arrest and DNA-damage-inducible, alpha 1.10388
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.10388
ALPP alkaline phosphatase, placental 1.10211
CAPZB capping protein (actin filament) muscle Z-line, beta 1.10211
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.10175
LZTFL1 leucine zipper transcription factor-like 1 1.10175
GAP43 growth associated protein 43 1.10069
CAMK2D calcium/calmodulin-dependent protein kinase II delta 1.10033
CCNA2 cyclin A2 1.09963
GSTA2 glutathione S-transferase alpha 2 1.09646
SRM spermidine synthase 1.09576
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.09506
ACO2 aconitase 2, mitochondrial 1.09471
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.09366
TMEM184B transmembrane protein 184B 1.09226
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 1.09226
ILDR2 immunoglobulin-like domain containing receptor 2 1.0919
GSTM2 glutathione S-transferase mu 2 (muscle) 1.09119
CFLAR CASP8 and FADD-like apoptosis regulator 1.09083
ZMYND8 zinc finger, MYND-type containing 8 1.08833
RRM2 ribonucleotide reductase M2 1.08833
GSTA3 glutathione S-transferase alpha 3 1.08762
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 1.08726
GRM5 glutamate receptor, metabotropic 5 1.08726
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.08726
UBE2I ubiquitin-conjugating enzyme E2I 1.08726
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 1.08549
UNG uracil-DNA glycosylase 1.08549
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.08266
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 1.08231
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 1.08196
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.08161
NCAN neurocan 1.08091
MAP2K1 mitogen-activated protein kinase kinase 1 1.08055
SOWAHA sosondowah ankyrin repeat domain family member A 1.08019
FN1 fibronectin 1 1.07911
MKI67 marker of proliferation Ki-67 1.07875
VCAM1 vascular cell adhesion molecule 1 1.07804
PPAP2C phosphatidic acid phosphatase type 2C 1.07553
GPX3 glutathione peroxidase 3 1.07518
IL33 interleukin 33 1.07482
MVP major vault protein 1.07482
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 1.07482
SMAD2 SMAD family member 2 1.07376
CKB creatine kinase, brain 1.07376
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.07093
CD47 CD47 molecule 1.07057
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 1.06952
DCAF6 DDB1 and CUL4 associated factor 6 1.06952
MAP3K12 mitogen-activated protein kinase kinase kinase 12 1.06952
NCALD neurocalcin delta 1.06917
CBLN1 cerebellin 1 precursor 1.06917
CPN1 carboxypeptidase N, polypeptide 1 1.06917
HEXA hexosaminidase A (alpha polypeptide) 1.06917
CD36 CD36 molecule (thrombospondin receptor) 1.06844
ORM1 orosomucoid 1 1.06808
SOCS3 suppressor of cytokine signaling 3 1.06661
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.06661
IL5 interleukin 5 1.06515
CDC6 cell division cycle 6 1.06515
KALRN kalirin, RhoGEF kinase 1.06297
STXBP1 syntaxin binding protein 1 1.06297
PCP4L1 Purkinje cell protein 4 like 1 1.06297
ERP29 endoplasmic reticulum protein 29 1.06261
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.06008
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.05972
EFNA2 ephrin-A2 1.059
PEX11B peroxisomal biogenesis factor 11 beta 1.05864
PPP1R7 protein phosphatase 1, regulatory subunit 7 1.05864
GNPAT glyceronephosphate O-acyltransferase 1.05828
FBXL3 F-box and leucine-rich repeat protein 3 1.05828
CCDC93 coiled-coil domain containing 93 1.05828
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 1.05828
COL4A4 collagen, type IV, alpha 4 1.05828
CRYM crystallin, mu 1.05721
PLP1 proteolipid protein 1 1.05721
NRP1 neuropilin 1 1.05685
MSMO1 methylsterol monooxygenase 1 1.05685
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 1.05685
GJA1 gap junction protein, alpha 1, 43kDa 1.05648
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.05498
CCND2 cyclin D2 1.05349
CLU clusterin 1.05312
XDH xanthine dehydrogenase 1.05312
PDE4A phosphodiesterase 4A, cAMP-specific 1.05089
CDK1 cyclin-dependent kinase 1 1.05089
MDH1 malate dehydrogenase 1, NAD (soluble) 1.05089
COIL coilin 1.04831
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.04831
ARMC8 armadillo repeat containing 8 1.04831
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.04831
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.04794
PKNOX2 PBX/knotted 1 homeobox 2 1.04794
KRAS Kirsten rat sarcoma viral oncogene homolog 1.04721
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.04684
AADAT aminoadipate aminotransferase 1.04538
TANK TRAF family member-associated NFKB activator 1.04501
MBP myelin basic protein 1.04276
FMO1 flavin containing monooxygenase 1 1.04276
IDI1 isopentenyl-diphosphate delta isomerase 1 1.04276
NSF N-ethylmaleimide-sensitive factor 1.03976
AQP4 aquaporin 4 1.03939
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.03939
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) 1.03939
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 1.03939
PLA2G12A phospholipase A2, group XIIA 1.03939
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.03939
ATM ATM serine/threonine kinase 1.03901
CPPED1 calcineurin-like phosphoesterase domain containing 1 1.03864
FER fer (fps/fes related) tyrosine kinase 1.03827
DLL4 delta-like 4 (Drosophila) 1.03789
RIOK2 RIO kinase 2 1.03752
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.03752
PGD phosphogluconate dehydrogenase 1.03493
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.03493
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.03493
CD14 CD14 molecule 1.03493
CASP12 caspase 12 (gene/pseudogene) 1.03493
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.03382
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.03382
CD44 CD44 molecule (Indian blood group) 1.03271
AGO4 argonaute RISC catalytic component 4 1.03271
OAT ornithine aminotransferase 1.03235
MCM7 minichromosome maintenance complex component 7 1.03197
ODC1 ornithine decarboxylase 1 1.03159
ADCY5 adenylate cyclase 5 1.02858
DAPK3 death-associated protein kinase 3 1.02821
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.02821
RHOQ ras homolog family member Q 1.02821
LMO7 LIM domain 7 1.02821
PRKD3 protein kinase D3 1.02821
TCF3 transcription factor 3 1.02821
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.02821
PDCD5 programmed cell death 5 1.02821
ADAT2 adenosine deaminase, tRNA-specific 2 1.02783
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.02708
IL1R1 interleukin 1 receptor, type I 1.02447
DHFR dihydrofolate reductase 1.02447
SQLE squalene epoxidase 1.02447
SQSTM1 sequestosome 1 1.02299
EIF4B eukaryotic translation initiation factor 4B 1.02299
GLRA1 glycine receptor, alpha 1 1.02299
TIMP1 TIMP metallopeptidase inhibitor 1 1.02151
EIF5 eukaryotic translation initiation factor 5 1.02114
LDB2 LIM domain binding 2 1.01928
TMEM63A transmembrane protein 63A 1.01928
NXPH3 neurexophilin 3 1.0189
FASN fatty acid synthase 1.0189
F10 coagulation factor X 1.01776
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.01776
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.01739
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.01739
DDR1 discoidin domain receptor tyrosine kinase 1 1.01739
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.01739
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.01701
ESR1 estrogen receptor 1 1.01474
CBR3 carbonyl reductase 3 1.01437
BIRC5 baculoviral IAP repeat containing 5 1.01361
CP ceruloplasmin (ferroxidase) 1.01324
EIF3A eukaryotic translation initiation factor 3, subunit A 1.01212
ASL argininosuccinate lyase 1.01212
GDF10 growth differentiation factor 10 1.01212
AK3 adenylate kinase 3 1.01212
SDS serine dehydratase 1.01212
FASLG Fas ligand (TNF superfamily, member 6) 1.01099
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.01099
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.01062
SDC4 syndecan 4 1.01062
NGLY1 N-glycanase 1 1.01025
PLXNB1 plexin B1 1.01025