Epiretinal Membrane Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An epiretinal membrane is a thin sheet of fibrous tissue that can develop on the surface of the macular area of the retina and cause a disturbance in vision. An epiretinal membrane area can develop on the thin macular area of the retin. An epiretinal membrane is also sometimes called a macular pucker, premacular fibrosis, surface wrinkling retinopathy or cellophane maculopathy. (Human Phenotype Ontology, HP_0100014)
External Link https://www.disgenet.org/browser/0/1/0/C0339543
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Genes

96 genes associated with the disease Epiretinal Membrane in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AMD1 adenosylmethionine decarboxylase 1
APC adenomatous polyposis coli
APLN apelin
APLNR apelin receptor
BDNF brain-derived neurotrophic factor
CALCR calcitonin receptor
CALR calreticulin
CAT catalase
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CD34 CD34 molecule
CUX1 cut-like homeobox 1
EDN1 endothelin 1
EDNRB endothelin receptor type B
EMP2 epithelial membrane protein 2
EPO erythropoietin
ETV5 ets variant 5
FANCF Fanconi anemia, complementation group F
FGF2 fibroblast growth factor 2 (basic)
FN1 fibronectin 1
GDNF glial cell derived neurotrophic factor
GFAP glial fibrillary acidic protein
GFRA1 GDNF family receptor alpha 1
GFRA2 GDNF family receptor alpha 2
GH1 growth hormone 1
GLI1 GLI family zinc finger 1
GORASP1 golgi reassembly stacking protein 1, 65kDa
HCLS1 hematopoietic cell-specific Lyn substrate 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-A major histocompatibility complex, class I, A
HMGB1 high mobility group box 1
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL17A interleukin 17A
IL2RB interleukin 2 receptor, beta
IL6 interleukin 6
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KHSRP KH-type splicing regulatory protein
LGALS1 lectin, galactoside-binding, soluble, 1
MAP1B microtubule-associated protein 1B
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MMRN1 multimerin 1
MYO7A myosin VIIA
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NF2 neurofibromin 2 (merlin)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLG plasminogen
PLXDC1 plexin domain containing 1
PLXNA2 plexin A2
PML promyelocytic leukemia
POSTN periostin, osteoblast specific factor
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PSIP1 PC4 and SFRS1 interacting protein 1
PTPRC protein tyrosine phosphatase, receptor type, C
PVR poliovirus receptor
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPE ribulose-5-phosphate-3-epimerase
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SNAI1 snail family zinc finger 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX2 SRY (sex determining region Y)-box 2
SP1 Sp1 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SYT1 synaptotagmin I
TCF3 transcription factor 3
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53BP2 tumor protein p53 binding protein 2
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
UPP1 uridine phosphorylase 1
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
USP9X ubiquitin specific peptidase 9, X-linked
VEGFA vascular endothelial growth factor A
VIT vitrin
WNK1 WNK lysine deficient protein kinase 1