| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.125299 |
| PLAT | plasminogen activator, tissue | 0.104126 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0811398 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0654123 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0629998 |
| NDRG1 | N-myc downstream regulated 1 | 0.0550586 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.053207 |
| RPS6 | ribosomal protein S6 | 0.0505374 |
| MYADM | myeloid-associated differentiation marker | 0.0440966 |
| FLNB | filamin B, beta | 0.0403526 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0397885 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.038685 |
| FLNA | filamin A, alpha | 0.0379719 |
| CSTB | cystatin B (stefin B) | 0.0378477 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0370514 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.036406 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0364015 |
| EGFR | epidermal growth factor receptor | 0.0348379 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0341447 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0341191 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0334118 |
| CD99 | CD99 molecule | 0.0321903 |
| S100A11 | S100 calcium binding protein A11 | 0.0320225 |
| FAM107B | family with sequence similarity 107, member B | 0.0306254 |
| STC1 | stanniocalcin 1 | 0.0288531 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0269652 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0260361 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0258213 |
| GDF15 | growth differentiation factor 15 | 0.025739 |
| RPS2 | ribosomal protein S2 | 0.0253069 |
| PODXL | podocalyxin-like | 0.0247737 |
| RPS3 | ribosomal protein S3 | 0.0247317 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0246914 |
| EZR | ezrin | 0.0238403 |
| MT2A | metallothionein 2A | 0.0238321 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0229748 |
| AXL | AXL receptor tyrosine kinase | 0.0229229 |
| RPL37A | ribosomal protein L37a | 0.0227738 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0226624 |
| GOLGA4 | golgin A4 | 0.0226567 |
| IL32 | interleukin 32 | 0.0224017 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0223571 |
| LMNA | lamin A/C | 0.0221576 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0221101 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.021648 |
| FTL | ferritin, light polypeptide | 0.0214404 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0213936 |
| TPI1 | triosephosphate isomerase 1 | 0.0213697 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0212791 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.021204 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0211982 |
| RPS19 | ribosomal protein S19 | 0.0210171 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0207882 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0207712 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0203275 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0202 |
| DTNA | dystrobrevin, alpha | 0.019799 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0197592 |
| VIM | vimentin | 0.0196056 |
| MEF2D | myocyte enhancer factor 2D | 0.0192379 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0190677 |
| RND3 | Rho family GTPase 3 | 0.0190677 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0187634 |
| RPS8 | ribosomal protein S8 | 0.018487 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0180254 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0179228 |
| PLXNA3 | plexin A3 | 0.0179073 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0179003 |
| RPS27 | ribosomal protein S27 | 0.0177677 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0177438 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0175855 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.017401 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0173565 |
| TLN1 | talin 1 | 0.0171169 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0170796 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0170769 |
| PFN1 | profilin 1 | 0.016955 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0169247 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0168322 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0167432 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0167098 |
| RPL5 | ribosomal protein L5 | 0.0165184 |
| RPL36 | ribosomal protein L36 | 0.0164702 |
| CLU | clusterin | 0.0164655 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0164631 |
| RARA | retinoic acid receptor, alpha | 0.0164259 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0162452 |
| RPS12 | ribosomal protein S12 | 0.0161427 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0160826 |
| PML | promyelocytic leukemia | 0.0156375 |
| EPAS1 | endothelial PAS domain protein 1 | 0.015572 |
| PLD3 | phospholipase D family, member 3 | 0.0155294 |
| L1CAM | L1 cell adhesion molecule | 0.0154915 |
| RPL31 | ribosomal protein L31 | 0.0154822 |
| RPS16 | ribosomal protein S16 | 0.0154331 |
| RPL36A | ribosomal protein L36a | 0.0154208 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0153186 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0152485 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0152328 |
| SERTAD2 | SERTA domain containing 2 | 0.0152006 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.244683 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.203897 |
| FBN1 | fibrillin 1 | -0.151348 |
| MAP1B | microtubule-associated protein 1B | -0.119466 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.111048 |
| CD44 | CD44 molecule (Indian blood group) | -0.106486 |
| AHNAK | AHNAK nucleoprotein | -0.106193 |
| NAV1 | neuron navigator 1 | -0.105668 |
| COL5A2 | collagen, type V, alpha 2 | -0.101797 |
| COL1A2 | collagen, type I, alpha 2 | -0.0905541 |
| GLIS3 | GLIS family zinc finger 3 | -0.0782583 |
| COL3A1 | collagen, type III, alpha 1 | -0.0780752 |
| CANX | calnexin | -0.0720478 |
| THBS2 | thrombospondin 2 | -0.0680278 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0650913 |
| LOX | lysyl oxidase | -0.0622008 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0605183 |
| ANXA2 | annexin A2 | -0.0592898 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0570341 |
| MEIS2 | Meis homeobox 2 | -0.0553734 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0543505 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0537856 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0537243 |
| DST | dystonin | -0.0525233 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.049839 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0490307 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0486868 |
| SUCNR1 | succinate receptor 1 | -0.0476884 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0475569 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0468329 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0462832 |
| CENPF | centromere protein F, 350/400kDa | -0.0452412 |
| TMSB4X | thymosin beta 4, X-linked | -0.0450515 |
| MAP4 | microtubule-associated protein 4 | -0.0449663 |
| RIGI | RNA sensor RIG-I | -0.044867 |
| RAI14 | retinoic acid induced 14 | -0.0446379 |
| APP | amyloid beta (A4) precursor protein | -0.0444368 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0429852 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0422251 |
| TPM4 | tropomyosin 4 | -0.0412848 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0409428 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0408051 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0403556 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0382934 |
| PRSS23 | protease, serine, 23 | -0.0382397 |
| EHBP1 | EH domain binding protein 1 | -0.0379828 |
| LDHA | lactate dehydrogenase A | -0.0368547 |
| CDK6 | cyclin-dependent kinase 6 | -0.0367342 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0366217 |
| PRELID2 | PRELI domain containing 2 | -0.0362821 |
| RRM2 | ribonucleotide reductase M2 | -0.0362054 |
| COL5A1 | collagen, type V, alpha 1 | -0.0360692 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0358367 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.03575 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.035723 |
| SMYD3 | SET and MYND domain containing 3 | -0.0357025 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0355597 |
| DIAPH3 | diaphanous-related formin 3 | -0.0355379 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0355101 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0349966 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0348505 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0347152 |
| ANLN | anillin, actin binding protein | -0.0334346 |
| ACTN4 | actinin, alpha 4 | -0.032916 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0328348 |
| VCL | vinculin | -0.0322311 |
| SPAG9 | sperm associated antigen 9 | -0.0320659 |
| HLA-C | major histocompatibility complex, class I, C | -0.0320494 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0319209 |
| ZNF217 | zinc finger protein 217 | -0.0312701 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0312383 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0312323 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0309907 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0306969 |
| MX2 | MX dynamin-like GTPase 2 | -0.0305152 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0304942 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0302391 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0299082 |
| PGK1 | phosphoglycerate kinase 1 | -0.0296501 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0296421 |
| HDAC9 | histone deacetylase 9 | -0.029267 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0290681 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0290044 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0286968 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0286645 |
| TUBB | tubulin, beta class I | -0.0286303 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0284835 |
| PXDN | peroxidasin | -0.0284092 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0278949 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0278608 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0278147 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0278053 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0277467 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0276568 |
| VEGFC | vascular endothelial growth factor C | -0.0276477 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0270797 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0268453 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0267425 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0265738 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0264479 |
