| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS2 | ribosomal protein S2 | 0.0803782 |
| RPS12 | ribosomal protein S12 | 0.0676845 |
| TUBA1B | tubulin, alpha 1b | 0.0434049 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0353951 |
| RPL37A | ribosomal protein L37a | 0.0321326 |
| TPM3 | tropomyosin 3 | 0.0312742 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0308137 |
| RPL4 | ribosomal protein L4 | 0.0303243 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0302908 |
| TPI1 | triosephosphate isomerase 1 | 0.0300405 |
| RPS3 | ribosomal protein S3 | 0.0298968 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0287741 |
| RPS17 | ribosomal protein S17 | 0.0285817 |
| MKI67 | marker of proliferation Ki-67 | 0.0269875 |
| ASPH | aspartate beta-hydroxylase | 0.0266076 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0264577 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0255413 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0253951 |
| YBX3 | Y box binding protein 3 | 0.0246291 |
| TUBA1C | tubulin, alpha 1c | 0.0240834 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0237259 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0234104 |
| FLNA | filamin A, alpha | 0.022795 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0226185 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0223354 |
| HELLS | helicase, lymphoid-specific | 0.0217944 |
| RPL21 | ribosomal protein L21 | 0.0214315 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0208726 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.020596 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0202334 |
| HMGA2 | high mobility group AT-hook 2 | 0.0200731 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0196757 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0196505 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0194612 |
| WDR43 | WD repeat domain 43 | 0.0191961 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0188151 |
| RPS6 | ribosomal protein S6 | 0.0186116 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0181269 |
| CBX5 | chromobox homolog 5 | 0.0180525 |
| PRDX1 | peroxiredoxin 1 | 0.0171046 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0170565 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0165415 |
| RPS7 | ribosomal protein S7 | 0.0164334 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0163546 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0161442 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0160339 |
| RPL26 | ribosomal protein L26 | 0.0157904 |
| CCNL1 | cyclin L1 | 0.0155793 |
| E2F7 | E2F transcription factor 7 | 0.0155597 |
| RPL18 | ribosomal protein L18 | 0.0152281 |
| DIAPH3 | diaphanous-related formin 3 | 0.0151735 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0145417 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0144988 |
| PCBP2 | poly(rC) binding protein 2 | 0.0142495 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0141957 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.01416 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0140568 |
| SET | SET nuclear proto-oncogene | 0.0140342 |
| SRPK2 | SRSF protein kinase 2 | 0.0138945 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0138633 |
| DHFR | dihydrofolate reductase | 0.0138504 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0136199 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0135902 |
| KIF1C | kinesin family member 1C | 0.0133758 |
| TMEM181 | transmembrane protein 181 | 0.0133239 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0129525 |
| RPLP2 | ribosomal protein, large, P2 | 0.0128378 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0125234 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0124583 |
| POLH | polymerase (DNA directed), eta | 0.0123897 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0123767 |
| CIP2A | cellular inhibitor of PP2A | 0.0123689 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0123229 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0122562 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0119681 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0118851 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | 0.0118526 |
| RPL5 | ribosomal protein L5 | 0.0118295 |
| RPS19 | ribosomal protein S19 | 0.0117469 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0117452 |
| LEMD3 | LEM domain containing 3 | 0.0117325 |
| RPS3A | ribosomal protein S3A | 0.0116503 |
| PLPP1 | phospholipid phosphatase 1 | 0.011404 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0114031 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0113657 |
| GSE1 | Gse1 coiled-coil protein | 0.0112622 |
| RPL7A | ribosomal protein L7a | 0.011229 |
| RPL27 | ribosomal protein L27 | 0.0111903 |
| AGRN | agrin | 0.0111865 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0111672 |
| TLN1 | talin 1 | 0.0111658 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0111577 |
| DOCK3 | dedicator of cytokinesis 3 | 0.011152 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0111028 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.010965 |
| TAF3 | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa | 0.0109176 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0108552 |
| SERF2 | small EDRK-rich factor 2 | 0.0108148 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0107889 |
| HDGF | hepatoma-derived growth factor | 0.0107561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | -0.220542 |
| VIM | vimentin | -0.187068 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.170162 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.114089 |
| MMP12 | matrix metallopeptidase 12 | -0.109299 |
| NLGN1 | neuroligin 1 | -0.0972455 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0956845 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0883083 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0852833 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0832408 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0813682 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0806344 |
| USP34 | ubiquitin specific peptidase 34 | -0.0792363 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0775666 |
| TENM3 | teneurin transmembrane protein 3 | -0.0762333 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0757604 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0699687 |
| MGAT4C | MGAT4 family, member C | -0.0698652 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0685125 |
| TXNRD1 | thioredoxin reductase 1 | -0.0670043 |
| ANXA1 | annexin A1 | -0.0663166 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0656832 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0614461 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0572252 |
| JMJD1C | jumonji domain containing 1C | -0.0552911 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0548753 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0541216 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0539801 |
| FTL | ferritin, light polypeptide | -0.0531628 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0524742 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0518354 |
| RPL35A | ribosomal protein L35a | -0.0511862 |
| RPL23 | ribosomal protein L23 | -0.0509985 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0508183 |
| NF1 | neurofibromin 1 | -0.0505177 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0492269 |
| PCDH7 | protocadherin 7 | -0.0490339 |
| LMO7 | LIM domain 7 | -0.0488878 |
| ZNF217 | zinc finger protein 217 | -0.0485472 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0481836 |
| TMSB10 | thymosin beta 10 | -0.0480942 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0478395 |
| VMP1 | vacuole membrane protein 1 | -0.0475213 |
| CPOX | coproporphyrinogen oxidase | -0.047483 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0470868 |
| FBXO11 | F-box protein 11 | -0.0466829 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0462569 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0454123 |
| PGK1 | phosphoglycerate kinase 1 | -0.0438943 |
| CCND1 | cyclin D1 | -0.0437593 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0436116 |
| SETD5 | SET domain containing 5 | -0.0428376 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0421171 |
| DST | dystonin | -0.0413655 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.040078 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0396699 |
| HMGA1 | high mobility group AT-hook 1 | -0.0396386 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0386582 |
| LDHA | lactate dehydrogenase A | -0.038334 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0379216 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0370005 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0364999 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0359922 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0353266 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0351877 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0349385 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0339403 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0338271 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0332738 |
| ZNF804A | zinc finger protein 804A | -0.0330151 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0322136 |
| SYT1 | synaptotagmin I | -0.0321954 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0316196 |
| TMEM131 | transmembrane protein 131 | -0.0312976 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.030877 |
| EHBP1 | EH domain binding protein 1 | -0.0307969 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0306893 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0305745 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0303813 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0302165 |
| RPL19 | ribosomal protein L19 | -0.030119 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0300369 |
| HDAC9 | histone deacetylase 9 | -0.0300169 |
| S100A6 | S100 calcium binding protein A6 | -0.0297383 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0296687 |
| TMEM41B | transmembrane protein 41B | -0.0294405 |
| RAB1A | RAB1A, member RAS oncogene family | -0.029322 |
| UBC | ubiquitin C | -0.0291941 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0291585 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0288833 |
| TAOK1 | TAO kinase 1 | -0.028443 |
| CDK6 | cyclin-dependent kinase 6 | -0.0281859 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0277025 |
| BPTF | bromodomain PHD finger transcription factor | -0.0275959 |
| MED13L | mediator complex subunit 13-like | -0.0275958 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0275393 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0274451 |
| POTEF | POTE ankyrin domain family, member F | -0.0273247 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0272734 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0271142 |
