| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCL2 | chemokine (C-C motif) ligand 2 | 0.134601 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0907806 |
| RPS2 | ribosomal protein S2 | 0.0861694 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0616833 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0603652 |
| ASPH | aspartate beta-hydroxylase | 0.0583304 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0442113 |
| CENPF | centromere protein F, 350/400kDa | 0.0434154 |
| TPM3 | tropomyosin 3 | 0.0426726 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0426694 |
| TLN1 | talin 1 | 0.0419439 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0375404 |
| FLNA | filamin A, alpha | 0.0357358 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0319979 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0317992 |
| RPS6 | ribosomal protein S6 | 0.031699 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0313715 |
| ANLN | anillin, actin binding protein | 0.0300419 |
| MKI67 | marker of proliferation Ki-67 | 0.0299577 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0291424 |
| RPL4 | ribosomal protein L4 | 0.0281151 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0275847 |
| RND3 | Rho family GTPase 3 | 0.0265118 |
| CADM1 | cell adhesion molecule 1 | 0.0254809 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0252328 |
| PTMA | prothymosin, alpha | 0.0251924 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0248419 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0239112 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0228491 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0226515 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0223386 |
| PRR13 | proline rich 13 | 0.0219088 |
| VIM | vimentin | 0.0214603 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0207444 |
| TUBA1B | tubulin, alpha 1b | 0.0205243 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0203067 |
| GDF15 | growth differentiation factor 15 | 0.0200898 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0198552 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0197568 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0192108 |
| HMGB2 | high mobility group box 2 | 0.0191476 |
| HDGF | hepatoma-derived growth factor | 0.0186854 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0184637 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0182323 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0179979 |
| CAVIN1 | caveolae associated protein 1 | 0.017853 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.0177896 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0177757 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0177543 |
| TMEM39A | transmembrane protein 39A | 0.01756 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0174549 |
| RPL26 | ribosomal protein L26 | 0.0174531 |
| RPS7 | ribosomal protein S7 | 0.0173091 |
| ARF1 | ADP-ribosylation factor 1 | 0.0172568 |
| H1-4 | H1.4 linker histone, cluster member | 0.0171359 |
| YME1L1 | YME1-like 1 ATPase | 0.0171002 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0167491 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0167246 |
| TPX2 | TPX2, microtubule-associated | 0.0165363 |
| FSTL1 | follistatin-like 1 | 0.0163056 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0162097 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0159759 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0159444 |
| TMF1 | TATA element modulatory factor 1 | 0.0159388 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0159014 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0158782 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.015792 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0157031 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0156893 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0156474 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0155335 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0148273 |
| SRP54 | signal recognition particle 54kDa | 0.0147922 |
| DSTN | destrin (actin depolymerizing factor) | 0.0147185 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.014637 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.0145514 |
| PLK2 | polo-like kinase 2 | 0.0144307 |
| TNS1 | tensin 1 | 0.0142812 |
| BRD4 | bromodomain containing 4 | 0.0141097 |
| RACK1 | receptor for activated C kinase 1 | 0.0137956 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0137793 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0137612 |
| RPL18 | ribosomal protein L18 | 0.0136947 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0136438 |
| AXL | AXL receptor tyrosine kinase | 0.0136104 |
| CD68 | CD68 molecule | 0.0135019 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0134561 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.013347 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.0130246 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.012973 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0129677 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.0128508 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0128141 |
| INSIG1 | insulin induced gene 1 | 0.0128097 |
| NCBP3 | nuclear cap binding subunit 3 | 0.0128017 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0127833 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0127454 |
| POM121 | POM121 transmembrane nucleoporin | 0.0127274 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0126304 |
| TPR | translocated promoter region, nuclear basket protein | 0.0125995 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.153464 |
| TXNRD1 | thioredoxin reductase 1 | -0.149926 |
| TMSB10 | thymosin beta 10 | -0.129556 |
| NDRG1 | N-myc downstream regulated 1 | -0.103625 |
| EXT1 | exostosin glycosyltransferase 1 | -0.101261 |
| GPC6 | glypican 6 | -0.0994536 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0817812 |
| B2M | beta-2-microglobulin | -0.0794992 |
| RPL35A | ribosomal protein L35a | -0.0752368 |
| RPL23 | ribosomal protein L23 | -0.0732226 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0700633 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0682844 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0646837 |
| RPLP1 | ribosomal protein, large, P1 | -0.0646747 |
| HLA-B | major histocompatibility complex, class I, B | -0.0608664 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0587408 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0586408 |
| CD44 | CD44 molecule (Indian blood group) | -0.0574292 |
| RNF213 | ring finger protein 213 | -0.057322 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0569197 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0552837 |
| KYNU | kynureninase | -0.0542239 |
| POTEF | POTE ankyrin domain family, member F | -0.0526312 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.051601 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0507737 |
| MX1 | MX dynamin-like GTPase 1 | -0.0496531 |
| RIGI | RNA sensor RIG-I | -0.0477417 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0475957 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0471463 |
| RPS19 | ribosomal protein S19 | -0.0469941 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0469849 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0460618 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0457806 |
| OSMR | oncostatin M receptor | -0.0445725 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0443889 |
| GLIS3 | GLIS family zinc finger 3 | -0.0441223 |
| PKM | pyruvate kinase, muscle | -0.0438023 |
| MORF4L2 | mortality factor 4 like 2 | -0.0433173 |
| RPS20 | ribosomal protein S20 | -0.0429786 |
| NRP2 | neuropilin 2 | -0.0422164 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0416304 |
| RPS4X | ribosomal protein S4, X-linked | -0.0416246 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0411272 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.040992 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0409186 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0407163 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0405811 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0404266 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0400449 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0392351 |
| MT2A | metallothionein 2A | -0.0391541 |
| RPL19 | ribosomal protein L19 | -0.0385974 |
| MAP1B | microtubule-associated protein 1B | -0.0385891 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0381498 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0379587 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0377455 |
| PLIN2 | perilipin 2 | -0.0377126 |
| RPS13 | ribosomal protein S13 | -0.0370479 |
| CALD1 | caldesmon 1 | -0.0368756 |
| VCL | vinculin | -0.0368336 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0366988 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0364889 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0361318 |
| RPS24 | ribosomal protein S24 | -0.036019 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.035725 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.035015 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0347224 |
| FRMD4A | FERM domain containing 4A | -0.0342807 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0342182 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.033566 |
| CDCP1 | CUB domain containing protein 1 | -0.0333157 |
| CALU | calumenin | -0.032617 |
| CA12 | carbonic anhydrase XII | -0.0324436 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0320205 |
| MSR1 | macrophage scavenger receptor 1 | -0.031931 |
| TUSC3 | tumor suppressor candidate 3 | -0.0318401 |
| MYOF | myoferlin | -0.0317234 |
| SAA2 | serum amyloid A2 | -0.0314199 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0314195 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0311472 |
| NFIB | nuclear factor I/B | -0.0309883 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0308289 |
| RPL31 | ribosomal protein L31 | -0.0306338 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0304436 |
| SEPTIN7 | septin 7 | -0.0301885 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0300214 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0300211 |
| RPL34 | ribosomal protein L34 | -0.029709 |
| UBC | ubiquitin C | -0.0290178 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0289114 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0287766 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0287659 |
| ZNF207 | zinc finger protein 207 | -0.0287458 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0285149 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0282777 |
| COG5 | component of oligomeric golgi complex 5 | -0.028263 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0281402 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0280205 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0278694 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0278375 |
