| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0983962 |
| RPS2 | ribosomal protein S2 | 0.0716006 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0546614 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0479623 |
| SMAD3 | SMAD family member 3 | 0.0413907 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0393268 |
| RPS12 | ribosomal protein S12 | 0.0360602 |
| PCBP2 | poly(rC) binding protein 2 | 0.0307823 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0298713 |
| RPS6 | ribosomal protein S6 | 0.0296025 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0290681 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0278869 |
| CCNL1 | cyclin L1 | 0.0267421 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0250165 |
| RPS3 | ribosomal protein S3 | 0.02433 |
| TOP1 | topoisomerase (DNA) I | 0.0240559 |
| FLNA | filamin A, alpha | 0.0237236 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0229588 |
| TPM3 | tropomyosin 3 | 0.0224248 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0223352 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0221032 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0220022 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0218027 |
| SERTAD2 | SERTA domain containing 2 | 0.0212473 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0207821 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0206351 |
| RPL4 | ribosomal protein L4 | 0.0202347 |
| TXNRD1 | thioredoxin reductase 1 | 0.0202338 |
| IPO7 | importin 7 | 0.0198039 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0192067 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.018939 |
| RTN4 | reticulon 4 | 0.0188308 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0187387 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0180918 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0176078 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.017592 |
| PNN | pinin, desmosome associated protein | 0.0174891 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0168005 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0166191 |
| RPS8 | ribosomal protein S8 | 0.0165132 |
| ITGB4 | integrin, beta 4 | 0.0156729 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0156303 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0155556 |
| TLN1 | talin 1 | 0.0154478 |
| ATP13A3 | ATPase type 13A3 | 0.0153902 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0153587 |
| YAP1 | Yes-associated protein 1 | 0.0152818 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.015085 |
| RPL13A | ribosomal protein L13a | 0.0150706 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0148502 |
| SF1 | splicing factor 1 | 0.0144328 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0140198 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0138447 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0138147 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0136303 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0135904 |
| HLA-A | major histocompatibility complex, class I, A | 0.0135873 |
| RPS7 | ribosomal protein S7 | 0.0133697 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0132963 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0132364 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0132283 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0131415 |
| ANO6 | anoctamin 6 | 0.012892 |
| WLS | wntless Wnt ligand secretion mediator | 0.0127904 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0125825 |
| TUFT1 | tuftelin 1 | 0.0124987 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0124494 |
| TUBA1B | tubulin, alpha 1b | 0.0124446 |
| RPL21 | ribosomal protein L21 | 0.0124341 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0122948 |
| BRD2 | bromodomain containing 2 | 0.0122601 |
| RPL5 | ribosomal protein L5 | 0.0121105 |
| AREG | amphiregulin | 0.0121025 |
| RNF19B | ring finger protein 19B | 0.0120597 |
| PLEC | plectin | 0.0120105 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0119496 |
| WDR43 | WD repeat domain 43 | 0.0117045 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0116523 |
| RACK1 | receptor for activated C kinase 1 | 0.0116412 |
| DUSP4 | dual specificity phosphatase 4 | 0.0116329 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0115492 |
| HDGF | hepatoma-derived growth factor | 0.0114807 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0113857 |
| HKDC1 | hexokinase domain containing 1 | 0.0113764 |
| AGRN | agrin | 0.0113233 |
| CDC25B | cell division cycle 25B | 0.0112445 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0110579 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0110208 |
| RPS17 | ribosomal protein S17 | 0.0109428 |
| HMGB2 | high mobility group box 2 | 0.010911 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0108883 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0108844 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0107955 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0107848 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0107042 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0106582 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0106143 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0105965 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0105466 |
| AXL | AXL receptor tyrosine kinase | 0.0105153 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.283542 |
| LMO7 | LIM domain 7 | -0.152314 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.148321 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.144078 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.12942 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.126164 |
| TMSB10 | thymosin beta 10 | -0.122305 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.112844 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.111821 |
| FLNB | filamin B, beta | -0.109901 |
| EGFR | epidermal growth factor receptor | -0.107249 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.105997 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.103821 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.103782 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.100833 |
| AHNAK | AHNAK nucleoprotein | -0.0997998 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0928503 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0886606 |
| LAMB3 | laminin, beta 3 | -0.0881334 |
| PGK1 | phosphoglycerate kinase 1 | -0.0877391 |
| LAMA4 | laminin, alpha 4 | -0.0860626 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0859733 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0859076 |
| S100A10 | S100 calcium binding protein A10 | -0.0839294 |
| ANXA2 | annexin A2 | -0.0824054 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0789527 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0779864 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0771993 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0756907 |
| PTMA | prothymosin, alpha | -0.0738972 |
| VCAN | versican | -0.0660637 |
| CD2AP | CD2-associated protein | -0.0643181 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0637995 |
| UBC | ubiquitin C | -0.0625651 |
| FERMT1 | fermitin family member 1 | -0.061309 |
| DIAPH2 | diaphanous-related formin 2 | -0.0596692 |
| LDHA | lactate dehydrogenase A | -0.0596649 |
| DSG2 | desmoglein 2 | -0.0589057 |
| EMP1 | epithelial membrane protein 1 | -0.0580605 |
| VIM | vimentin | -0.0573689 |
| EZR | ezrin | -0.0573318 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0556187 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0549129 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0545897 |
| NPSR1 | neuropeptide S receptor 1 | -0.0545422 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0543825 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0525146 |
| TRRAP | transformation/transcription domain-associated protein | -0.0519578 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0508164 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0506413 |
| CALU | calumenin | -0.0505063 |
| POTEF | POTE ankyrin domain family, member F | -0.050268 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0495891 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.049484 |
| FBXO11 | F-box protein 11 | -0.0491411 |
| PERP | PERP, TP53 apoptosis effector | -0.0490516 |
| HMGA1 | high mobility group AT-hook 1 | -0.0488434 |
| STK39 | serine threonine kinase 39 | -0.0483334 |
| ARF4 | ADP-ribosylation factor 4 | -0.048053 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0477684 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0474525 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0466318 |
| SBF2 | SET binding factor 2 | -0.0463998 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0460233 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0459866 |
| S100A6 | S100 calcium binding protein A6 | -0.0437727 |
| TXNIP | thioredoxin interacting protein | -0.0437359 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0426334 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0416838 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0412135 |
| LAMC2 | laminin, gamma 2 | -0.0409738 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0409558 |
| NDRG1 | N-myc downstream regulated 1 | -0.0407915 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0406976 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0404446 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0404159 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0403097 |
| KLF6 | Kruppel-like factor 6 | -0.0403077 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0401629 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0399585 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0398862 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0395901 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0394354 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0393735 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0392922 |
| DIAPH1 | diaphanous-related formin 1 | -0.0389186 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0389016 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0384434 |
| RASAL2 | RAS protein activator like 2 | -0.0380337 |
| KLK10 | kallikrein-related peptidase 10 | -0.0380236 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0377022 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0374751 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0368598 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0366485 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0362786 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0361256 |
| CANX | calnexin | -0.0360478 |
| SP100 | SP100 nuclear antigen | -0.0359746 |
| ACTN4 | actinin, alpha 4 | -0.0355545 |
| FNDC3B | fibronectin type III domain containing 3B | -0.035388 |
