| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.101668 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0778408 |
| VMP1 | vacuole membrane protein 1 | 0.0549028 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0492523 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0418403 |
| KAZN | kazrin, periplakin interacting protein | 0.0389946 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0387466 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0375517 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0311378 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0311331 |
| TENM2 | teneurin transmembrane protein 2 | 0.0306054 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0300925 |
| CCNL1 | cyclin L1 | 0.0293984 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0278871 |
| SMAD3 | SMAD family member 3 | 0.0263787 |
| WWOX | WW domain containing oxidoreductase | 0.0259379 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0253376 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0252685 |
| MSI2 | musashi RNA-binding protein 2 | 0.0250956 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0246019 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0241148 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0240651 |
| EXT1 | exostosin glycosyltransferase 1 | 0.023158 |
| MED13L | mediator complex subunit 13-like | 0.0229876 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0222018 |
| GSE1 | Gse1 coiled-coil protein | 0.0219129 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.021679 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0215324 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0215117 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0211826 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0210836 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0207389 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0205247 |
| FOXN3 | forkhead box N3 | 0.0200767 |
| DENND1A | DENN/MADD domain containing 1A | 0.0200419 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0197009 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0195101 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0195029 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.018782 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0181454 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0179004 |
| SUSD6 | sushi domain containing 6 | 0.0178446 |
| MYO10 | myosin X | 0.0177599 |
| TMEM178B | transmembrane protein 178B | 0.0177275 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.01769 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.0176356 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0172949 |
| EXOC4 | exocyst complex component 4 | 0.0172617 |
| RPS2 | ribosomal protein S2 | 0.0171685 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0168264 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0167418 |
| WWC1 | WW and C2 domain containing 1 | 0.0167198 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.0167047 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0166432 |
| FAM168A | family with sequence similarity 168, member A | 0.0166115 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0165038 |
| PCGF2 | polycomb group ring finger 2 | 0.0165006 |
| GPHN | gephyrin | 0.0163769 |
| GPC6 | glypican 6 | 0.0162394 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0161704 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0158873 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 0.0156126 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0154941 |
| AUTS2 | autism susceptibility candidate 2 | 0.0153921 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0153133 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.015215 |
| CUX1 | cut-like homeobox 1 | 0.014869 |
| MACROD1 | MACRO domain containing 1 | 0.0148651 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0148525 |
| TBC1D5 | TBC1 domain family, member 5 | 0.014793 |
| FBXO32 | F-box protein 32 | 0.0146827 |
| OLA1 | Obg-like ATPase 1 | 0.0146633 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0146589 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0145684 |
| TOP1 | topoisomerase (DNA) I | 0.014491 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0144149 |
| PGR | progesterone receptor | 0.0143364 |
| PRLR | prolactin receptor | 0.0143314 |
| SRPK2 | SRSF protein kinase 2 | 0.0142316 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0142065 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0141778 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0138255 |
| XPO1 | exportin 1 | 0.013811 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0137018 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0136911 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0136209 |
| PNN | pinin, desmosome associated protein | 0.0135818 |
| YAP1 | Yes-associated protein 1 | 0.0135004 |
| TP53INP1 | tumor protein p53 inducible nuclear protein 1 | 0.0134919 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0132563 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0131091 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.0129376 |
| TFRC | transferrin receptor | 0.0128361 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0128132 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0127446 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0125907 |
| RORA | RAR-related orphan receptor A | 0.0125775 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0125674 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0125353 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0125244 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.177807 |
| RPL19 | ribosomal protein L19 | -0.170059 |
| RPL23 | ribosomal protein L23 | -0.128635 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.123273 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.11869 |
| ACACA | acetyl-CoA carboxylase alpha | -0.110028 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.108298 |
| ASPH | aspartate beta-hydroxylase | -0.0961651 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.083024 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0691853 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0678558 |
| ACTG1 | actin gamma 1 | -0.0649258 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.064855 |
| PGK1 | phosphoglycerate kinase 1 | -0.0574201 |
| LDHA | lactate dehydrogenase A | -0.0567295 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0556364 |
| CEP250 | centrosomal protein 250kDa | -0.0532118 |
| CLTC | clathrin, heavy chain (Hc) | -0.0531521 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0529652 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0463916 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0446602 |
| KRT19 | keratin 19, type I | -0.0445671 |
| ENO1 | enolase 1, (alpha) | -0.0431613 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0427495 |
| OSMR | oncostatin M receptor | -0.0427087 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0423149 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0422877 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.042143 |
| POTEF | POTE ankyrin domain family, member F | -0.0416584 |
| CCND1 | cyclin D1 | -0.0406814 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0402651 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0399861 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0391764 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0374854 |
| TMSB10 | thymosin beta 10 | -0.0370741 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.037074 |
| CCNI | cyclin I | -0.0364538 |
| AHNAK | AHNAK nucleoprotein | -0.0363362 |
| LMAN1 | lectin, mannose-binding, 1 | -0.036281 |
| SBF2 | SET binding factor 2 | -0.0357413 |
| PTMA | prothymosin, alpha | -0.0356735 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0356494 |
| ZNF652 | zinc finger protein 652 | -0.0352889 |
| TMEM123 | transmembrane protein 123 | -0.034884 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0347985 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0344667 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0340511 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0332739 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0328479 |
| KRT18 | keratin 18, type I | -0.0318382 |
| NDRG1 | N-myc downstream regulated 1 | -0.0314151 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0312116 |
| KRT7 | keratin 7, type II | -0.0307113 |
| FADS2 | fatty acid desaturase 2 | -0.0304461 |
| RAB7A | RAB7A, member RAS oncogene family | -0.030289 |
| TPM4 | tropomyosin 4 | -0.030037 |
| FOXO3 | forkhead box O3 | -0.0298449 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0296011 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0291655 |
| SP100 | SP100 nuclear antigen | -0.0286122 |
| TMSB4X | thymosin beta 4, X-linked | -0.02841 |
| SETD5 | SET domain containing 5 | -0.0284032 |
| CANX | calnexin | -0.0281155 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.0277426 |
| RPL35A | ribosomal protein L35a | -0.0271908 |
| S100A6 | S100 calcium binding protein A6 | -0.0269376 |
| INTS6 | integrator complex subunit 6 | -0.026507 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0262644 |
| TMC5 | transmembrane channel-like 5 | -0.0261395 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0259975 |
| GLCCI1 | glucocorticoid induced 1 | -0.0259467 |
| S100A9 | S100 calcium binding protein A9 | -0.025812 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0257852 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.025478 |
| S100A14 | S100 calcium binding protein A14 | -0.0254412 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0250653 |
| KRT8 | keratin 8, type II | -0.0250069 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0249254 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.024842 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0247487 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.0244302 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | -0.0242705 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0242006 |
| ATXN1 | ataxin 1 | -0.0241819 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0241343 |
| AHR | aryl hydrocarbon receptor | -0.0239407 |
| DSTN | destrin (actin depolymerizing factor) | -0.0238415 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0237892 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0237633 |
| LASP1 | LIM and SH3 protein 1 | -0.0235409 |
| CD164 | CD164 molecule, sialomucin | -0.0234923 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.023429 |
| DSG2 | desmoglein 2 | -0.0234038 |
| ANXA2 | annexin A2 | -0.0232894 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0228024 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0223101 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0223064 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0222404 |
| FNDC3A | fibronectin type III domain containing 3A | -0.022232 |
| PRR11 | proline rich 11 | -0.0221671 |
