| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| JMJD1C | jumonji domain containing 1C | 0.0535867 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0446544 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0438644 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0425765 |
| DST | dystonin | 0.042065 |
| GPHN | gephyrin | 0.0419902 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0394285 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0388953 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0382781 |
| ZNF292 | zinc finger protein 292 | 0.037863 |
| AUTS2 | autism susceptibility candidate 2 | 0.0377831 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0364209 |
| QKI | QKI, KH domain containing, RNA binding | 0.0350871 |
| KIAA1958 | KIAA1958 | 0.0336994 |
| NUP58 | nucleoporin 58 | 0.0333614 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0333335 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.032722 |
| HELZ | helicase with zinc finger | 0.0325726 |
| SRPK2 | SRSF protein kinase 2 | 0.0324852 |
| RTN4 | reticulon 4 | 0.0318554 |
| RNF150 | ring finger protein 150 | 0.0313902 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0313073 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0306297 |
| MEF2A | myocyte enhancer factor 2A | 0.0302877 |
| PDS5B | PDS5 cohesin associated factor B | 0.0296008 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0294874 |
| MED13L | mediator complex subunit 13-like | 0.0293873 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.028398 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0279321 |
| FNBP1L | formin binding protein 1-like | 0.0277535 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0273589 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0272208 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0268289 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0263813 |
| H1-0 | H1.0 linker histone | 0.0263047 |
| CCNL1 | cyclin L1 | 0.025825 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0257535 |
| OGA | O-GlcNAcase | 0.0257111 |
| BBX | bobby sox homolog (Drosophila) | 0.0256926 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0255355 |
| PCBP2 | poly(rC) binding protein 2 | 0.0254278 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0253606 |
| XPO1 | exportin 1 | 0.0252987 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0251361 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0248158 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0246284 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0243997 |
| FAM162A | family with sequence similarity 162, member A | 0.0242316 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0239784 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0238631 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0237867 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0237383 |
| PTK2 | protein tyrosine kinase 2 | 0.0236384 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0235534 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0233244 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0232661 |
| PCNX1 | pecanex 1 | 0.0232128 |
| PRELID2 | PRELI domain containing 2 | 0.0231012 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0229562 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.022862 |
| ZNF638 | zinc finger protein 638 | 0.0228253 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0225901 |
| IPO7 | importin 7 | 0.0224549 |
| SEPTIN7 | septin 7 | 0.0223363 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0222422 |
| NEK7 | NIMA-related kinase 7 | 0.0221243 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0219679 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0217518 |
| PHF21A | PHD finger protein 21A | 0.0217034 |
| TNRC6A | trinucleotide repeat containing 6A | 0.021697 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0216217 |
| RLF | rearranged L-myc fusion | 0.0216053 |
| TPI1 | triosephosphate isomerase 1 | 0.0215778 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0215439 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0215275 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0214914 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0212622 |
| RNF145 | ring finger protein 145 | 0.0211219 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0211081 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0209614 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0209593 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0207393 |
| PARD3 | par-3 family cell polarity regulator | 0.0206814 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0203872 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0203612 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0202782 |
| TPD52 | tumor protein D52 | 0.0200823 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0200727 |
| EXOC6B | exocyst complex component 6B | 0.0198956 |
| EGR1 | early growth response 1 | 0.0197931 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0196947 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0196937 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0196272 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0195818 |
| MXI1 | MAX interactor 1, dimerization protein | 0.019527 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0193753 |
| CDC73 | cell division cycle 73 | 0.0193712 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.01937 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0192837 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0192649 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.183423 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.145872 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.137 |
| RAD51B | RAD51 paralog B | -0.134414 |
| TENM3 | teneurin transmembrane protein 3 | -0.132907 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.126109 |
| NEBL | nebulette | -0.125747 |
| NPAS3 | neuronal PAS domain protein 3 | -0.105925 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105671 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0942158 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0917929 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0772251 |
| ZNF608 | zinc finger protein 608 | -0.0568891 |
| ACTG1 | actin gamma 1 | -0.0556748 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0543292 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0511157 |
| CADM2 | cell adhesion molecule 2 | -0.0510908 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0501139 |
| CDH18 | cadherin 18, type 2 | -0.0496177 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0447238 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0445361 |
| PTMA | prothymosin, alpha | -0.0427006 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0425941 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0400401 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0366915 |
| CANX | calnexin | -0.0365362 |
| ATP9A | ATPase, class II, type 9A | -0.0363792 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -0.0346203 |
| RPS8 | ribosomal protein S8 | -0.0338675 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0336688 |
| RPLP1 | ribosomal protein, large, P1 | -0.0325964 |
| RCC1 | regulator of chromosome condensation 1 | -0.032289 |
| ATP11A | ATPase, class VI, type 11A | -0.0305319 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0301286 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0292345 |
| FMNL2 | formin-like 2 | -0.0280497 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0275909 |
| RPL37A | ribosomal protein L37a | -0.0273122 |
| ENO1 | enolase 1, (alpha) | -0.0267931 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0260149 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0258568 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0258311 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0257672 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0255851 |
| TMSB10 | thymosin beta 10 | -0.0252189 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0249183 |
| MLIP | muscular LMNA-interacting protein | -0.0248462 |
| RPL11 | ribosomal protein L11 | -0.0245756 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0242732 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0238496 |
| RPL34 | ribosomal protein L34 | -0.0232277 |
| RPS24 | ribosomal protein S24 | -0.0229632 |
| AEBP2 | AE binding protein 2 | -0.0228637 |
| GAB2 | GRB2-associated binding protein 2 | -0.0227576 |
| BPTF | bromodomain PHD finger transcription factor | -0.0226934 |
| UBAP2 | ubiquitin associated protein 2 | -0.022581 |
| RPS29 | ribosomal protein S29 | -0.0225667 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0223644 |
| RPL26 | ribosomal protein L26 | -0.0221058 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0218625 |
| EMP1 | epithelial membrane protein 1 | -0.0217475 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0217428 |
| KCNH5 | potassium channel, voltage gated eag related subfamily H, member 5 | -0.0216722 |
| RPL38 | ribosomal protein L38 | -0.0216328 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0215238 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0211642 |
| RPL31 | ribosomal protein L31 | -0.0209677 |
| RPS3 | ribosomal protein S3 | -0.020925 |
| DENND1A | DENN/MADD domain containing 1A | -0.0208597 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0205338 |
| PYGL | phosphorylase, glycogen, liver | -0.0203097 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0202808 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0201713 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | -0.020171 |
| RPS27A | ribosomal protein S27a | -0.019764 |
| RPL30 | ribosomal protein L30 | -0.019692 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0191332 |
| RPS6 | ribosomal protein S6 | -0.0189698 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0187434 |
| USP34 | ubiquitin specific peptidase 34 | -0.0185702 |
| BNC2 | basonuclin 2 | -0.0181379 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0181152 |
| INTS6 | integrator complex subunit 6 | -0.0179391 |
| TBCA | tubulin folding cofactor A | -0.0178558 |
| HMGB1 | high mobility group box 1 | -0.0178228 |
| RPL35A | ribosomal protein L35a | -0.0177765 |
| RPS16 | ribosomal protein S16 | -0.0175637 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0174883 |
| HDAC4 | histone deacetylase 4 | -0.0173981 |
| UBE3C | ubiquitin protein ligase E3C | -0.0173609 |
| RPS12 | ribosomal protein S12 | -0.0167185 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.016629 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0164611 |
| RPLP2 | ribosomal protein, large, P2 | -0.0163169 |
| RPL36 | ribosomal protein L36 | -0.0163022 |
| HMGA1 | high mobility group AT-hook 1 | -0.0162286 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0160102 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0159945 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.015946 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0159279 |
