| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.14366 |
| VGF | VGF nerve growth factor inducible | 0.0948831 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0654509 |
| MT2A | metallothionein 2A | 0.0594277 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0541307 |
| FMNL2 | formin-like 2 | 0.0482746 |
| EGR1 | early growth response 1 | 0.0466975 |
| PTMA | prothymosin, alpha | 0.0427243 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0402258 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.037437 |
| CABIN1 | calcineurin binding protein 1 | 0.0372572 |
| PTCHD4 | patched domain containing 4 | 0.0367091 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0354216 |
| RPS6 | ribosomal protein S6 | 0.033362 |
| RPS8 | ribosomal protein S8 | 0.0317524 |
| RPS19 | ribosomal protein S19 | 0.0316579 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0315533 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.030309 |
| FTL | ferritin, light polypeptide | 0.029952 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0297622 |
| RPS12 | ribosomal protein S12 | 0.0297092 |
| GDF15 | growth differentiation factor 15 | 0.0295797 |
| RPL37A | ribosomal protein L37a | 0.0274782 |
| FLNB | filamin B, beta | 0.0273925 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0268356 |
| POM121C | POM121 transmembrane nucleoporin C | 0.026632 |
| RUNX1 | runt-related transcription factor 1 | 0.0265207 |
| RPL36 | ribosomal protein L36 | 0.0264669 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0262134 |
| HLA-B | major histocompatibility complex, class I, B | 0.0252871 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0243222 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0239127 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0238663 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0234199 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0229806 |
| FBXO42 | F-box protein 42 | 0.0226737 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0222634 |
| STXBP1 | syntaxin binding protein 1 | 0.0222573 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0222443 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.022211 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0219332 |
| SBF2 | SET binding factor 2 | 0.0217106 |
| PARVB | parvin, beta | 0.021575 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0213387 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0213034 |
| TNPO3 | transportin 3 | 0.020972 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.020776 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0206993 |
| RPLP1 | ribosomal protein, large, P1 | 0.0204496 |
| RPS29 | ribosomal protein S29 | 0.0202911 |
| PTK2 | protein tyrosine kinase 2 | 0.0196606 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0195583 |
| TPR | translocated promoter region, nuclear basket protein | 0.0194806 |
| RPS3 | ribosomal protein S3 | 0.0193957 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.0193626 |
| NBAS | neuroblastoma amplified sequence | 0.0189455 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.0189238 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0188759 |
| CTBP2 | C-terminal binding protein 2 | 0.0188439 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0188158 |
| RPS2 | ribosomal protein S2 | 0.0186993 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0185157 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0183355 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0180839 |
| RPS13 | ribosomal protein S13 | 0.0179615 |
| RPLP2 | ribosomal protein, large, P2 | 0.0178003 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0177517 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0176089 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.017597 |
| RPL12 | ribosomal protein L12 | 0.0172099 |
| RPL28 | ribosomal protein L28 | 0.0171877 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0168517 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0167635 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0164398 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0163492 |
| RPL10A | ribosomal protein L10a | 0.0163092 |
| ZC3H7A | zinc finger CCCH-type containing 7A | 0.0162624 |
| RPL30 | ribosomal protein L30 | 0.0162596 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0161917 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0159867 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0158012 |
| RPL26 | ribosomal protein L26 | 0.0157397 |
| RPS17 | ribosomal protein S17 | 0.0157172 |
| SERF2 | small EDRK-rich factor 2 | 0.0157055 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0154968 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0154931 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0154872 |
| OGA | O-GlcNAcase | 0.0152441 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0152376 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0152268 |
| RPL9 | ribosomal protein L9 | 0.0151864 |
| YBX3 | Y box binding protein 3 | 0.0151235 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0150531 |
| CTTNBP2 | cortactin binding protein 2 | 0.0150038 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0149361 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0148537 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0148022 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0147401 |
| MEF2A | myocyte enhancer factor 2A | 0.0147175 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.014643 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.491255 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.126416 |
| GPC6 | glypican 6 | -0.121653 |
| FMN1 | formin 1 | -0.113082 |
| NLGN1 | neuroligin 1 | -0.110807 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.104394 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.102623 |
| MACROD2 | MACRO domain containing 2 | -0.101993 |
| TNNC1 | troponin C type 1 (slow) | -0.0904527 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0850539 |
| DST | dystonin | -0.0782561 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0714114 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0713973 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0700385 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0661854 |
| PGK1 | phosphoglycerate kinase 1 | -0.0636177 |
| DCT | dopachrome tautomerase | -0.0616541 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0606716 |
| HMCN1 | hemicentin 1 | -0.0584681 |
| EHBP1 | EH domain binding protein 1 | -0.0543104 |
| PRELID2 | PRELI domain containing 2 | -0.0502122 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0500634 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0494339 |
| PCDH7 | protocadherin 7 | -0.048451 |
| AHNAK | AHNAK nucleoprotein | -0.048374 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0437352 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0436122 |
| NAV3 | neuron navigator 3 | -0.0429869 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0403069 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0397191 |
| LDHA | lactate dehydrogenase A | -0.0395938 |
| ASPH | aspartate beta-hydroxylase | -0.0392871 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0386458 |
| APP | amyloid beta (A4) precursor protein | -0.0378934 |
| OSMR | oncostatin M receptor | -0.0377311 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.037176 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0366911 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0366039 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | -0.0360529 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0357877 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.033617 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0332452 |
| SRPK2 | SRSF protein kinase 2 | -0.032399 |
| CDK14 | cyclin-dependent kinase 14 | -0.0323423 |
| NAV1 | neuron navigator 1 | -0.0322031 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0318106 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0309731 |
| DPYD | dihydropyrimidine dehydrogenase | -0.030896 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0307277 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0302647 |
| LAMB1 | laminin, beta 1 | -0.0302163 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0298787 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0293146 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0292548 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0292348 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0291193 |
| OXR1 | oxidation resistance 1 | -0.0289754 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0289604 |
| GSN | gelsolin | -0.0286972 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0278763 |
| PI15 | peptidase inhibitor 15 | -0.0277065 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.027444 |
| LSAMP | limbic system-associated membrane protein | -0.0273616 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0270333 |
| SSH1 | slingshot protein phosphatase 1 | -0.0265991 |
| SMYD3 | SET and MYND domain containing 3 | -0.0265438 |
| TMEM178B | transmembrane protein 178B | -0.0264945 |
| ENO1 | enolase 1, (alpha) | -0.0264905 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0263793 |
| NRP2 | neuropilin 2 | -0.0260584 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0260041 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0260033 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0259784 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0257742 |
| CANX | calnexin | -0.0253978 |
| PKM | pyruvate kinase, muscle | -0.0250655 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0249569 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0248046 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0247291 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0245895 |
| ANXA2 | annexin A2 | -0.0245577 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0245484 |
| UTRN | utrophin | -0.0242947 |
| TULP4 | tubby like protein 4 | -0.0241936 |
| RNF213 | ring finger protein 213 | -0.0241851 |
| HBP1 | HMG-box transcription factor 1 | -0.0240514 |
| CDH19 | cadherin 19, type 2 | -0.0236603 |
| ACTN4 | actinin, alpha 4 | -0.0234482 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0234361 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0230269 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0229251 |
| SYPL1 | synaptophysin-like 1 | -0.0228947 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0227836 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0222162 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0216367 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.0215051 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0214069 |
| NAV2 | neuron navigator 2 | -0.0213618 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0209801 |
| MTPN | myotrophin | -0.020815 |
