| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.0908219 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0787288 |
| TGM2 | transglutaminase 2 | 0.0617694 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0614064 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0547995 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.053549 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0501923 |
| RAD51B | RAD51 paralog B | 0.0438341 |
| VEGFA | vascular endothelial growth factor A | 0.0404235 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0380658 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0379983 |
| NDRG1 | N-myc downstream regulated 1 | 0.0379458 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0356712 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0349511 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0344921 |
| RPS2 | ribosomal protein S2 | 0.0343831 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0343555 |
| RPS6 | ribosomal protein S6 | 0.0326459 |
| FLNA | filamin A, alpha | 0.0317567 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0316783 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0303185 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296396 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0286827 |
| EGR1 | early growth response 1 | 0.028603 |
| AGRN | agrin | 0.0284158 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0275215 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0272208 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0267856 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0264734 |
| TPM3 | tropomyosin 3 | 0.0259792 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0254996 |
| CMIP | c-Maf inducing protein | 0.02526 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.025001 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.02441 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0242025 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.024091 |
| FOSL2 | FOS-like antigen 2 | 0.0238324 |
| FAM107B | family with sequence similarity 107, member B | 0.0235966 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0232795 |
| RPS12 | ribosomal protein S12 | 0.0232472 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0232453 |
| DUSP5 | dual specificity phosphatase 5 | 0.023167 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0231217 |
| MCL1 | myeloid cell leukemia 1 | 0.022982 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0229388 |
| RPL4 | ribosomal protein L4 | 0.0228797 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.022649 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0226325 |
| PKM | pyruvate kinase, muscle | 0.022457 |
| TAPBP | TAP binding protein (tapasin) | 0.0222535 |
| AXL | AXL receptor tyrosine kinase | 0.0215101 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0209964 |
| APOL1 | apolipoprotein L, 1 | 0.0209759 |
| NAV2 | neuron navigator 2 | 0.020969 |
| TMEM51 | transmembrane protein 51 | 0.020644 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.020446 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0203398 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0201913 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0201833 |
| ANO6 | anoctamin 6 | 0.0199544 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0199318 |
| ECE1 | endothelin converting enzyme 1 | 0.0195419 |
| TUBA1B | tubulin, alpha 1b | 0.0192046 |
| RPS17 | ribosomal protein S17 | 0.0191694 |
| LAMA5 | laminin, alpha 5 | 0.0191514 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0191104 |
| CENPF | centromere protein F, 350/400kDa | 0.0189185 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0188738 |
| MKI67 | marker of proliferation Ki-67 | 0.0187514 |
| KIAA1217 | KIAA1217 | 0.018594 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0183059 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0181187 |
| PLAT | plasminogen activator, tissue | 0.0180976 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0180914 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0179917 |
| FOSL1 | FOS-like antigen 1 | 0.0178698 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0176472 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0173637 |
| CCNL1 | cyclin L1 | 0.0173537 |
| DUOX2 | dual oxidase 2 | 0.0171494 |
| CFB | complement factor B | 0.0170765 |
| LCN2 | lipocalin 2 | 0.0169143 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0168381 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0167412 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0166234 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0163802 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0162573 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0161884 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0161754 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0161151 |
| NOTCH2 | notch 2 | 0.0158251 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.015516 |
| PCBP2 | poly(rC) binding protein 2 | 0.0154715 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0152864 |
| HPCAL1 | hippocalcin-like 1 | 0.015254 |
| SEPTIN9 | septin 9 | 0.0151002 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.015043 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0150345 |
| ZNF395 | zinc finger protein 395 | 0.0146186 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0145707 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.211175 |
| TMSB10 | thymosin beta 10 | -0.138286 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.124587 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.107645 |
| PTMA | prothymosin, alpha | -0.105189 |
| MT1X | metallothionein 1X | -0.0967752 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0950985 |
| MT2A | metallothionein 2A | -0.0904382 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0898186 |
| LMO7 | LIM domain 7 | -0.0871356 |
| MMP7 | matrix metallopeptidase 7 | -0.0819144 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0791244 |
| PGK1 | phosphoglycerate kinase 1 | -0.0774319 |
| TMSB4X | thymosin beta 4, X-linked | -0.0769866 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0749063 |
| LAMB3 | laminin, beta 3 | -0.0745604 |
| CD2AP | CD2-associated protein | -0.0728347 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0718336 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0699166 |
| SPAG9 | sperm associated antigen 9 | -0.0669381 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0666234 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0631123 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0629704 |
| CP | ceruloplasmin (ferroxidase) | -0.0618834 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0593667 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.058764 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0587597 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0571128 |
| AHNAK | AHNAK nucleoprotein | -0.0557936 |
| EHBP1 | EH domain binding protein 1 | -0.0546401 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.053717 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0529166 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0513552 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0509691 |
| HLA-B | major histocompatibility complex, class I, B | -0.0506567 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0505523 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0503412 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0501288 |
| JMJD1C | jumonji domain containing 1C | -0.0501225 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0500486 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0500342 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0498965 |
| ACTG1 | actin gamma 1 | -0.0497939 |
| RASAL2 | RAS protein activator like 2 | -0.0489018 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0488971 |
| ERBIN | erbb2 interacting protein | -0.0482662 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0481603 |
| FTL | ferritin, light polypeptide | -0.0463287 |
| TSC22D2 | TSC22 domain family, member 2 | -0.046321 |
| CANX | calnexin | -0.0461982 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0455838 |
| ANXA2 | annexin A2 | -0.0443376 |
| RBM39 | RNA binding motif protein 39 | -0.0439129 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0438445 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0437519 |
| APP | amyloid beta (A4) precursor protein | -0.0430641 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0415411 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0412331 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0411511 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0409882 |
| MCU | mitochondrial calcium uniporter | -0.040793 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0401214 |
| OGA | O-GlcNAcase | -0.039805 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0394249 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0393537 |
| DST | dystonin | -0.0385975 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0384392 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0384018 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0382656 |
| PARD3 | par-3 family cell polarity regulator | -0.0381159 |
| S100A6 | S100 calcium binding protein A6 | -0.0374412 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0372725 |
| DSG2 | desmoglein 2 | -0.0369109 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0367388 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0366548 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0365424 |
| B2M | beta-2-microglobulin | -0.0365289 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0364307 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0362235 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.035854 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0358188 |
| MEF2A | myocyte enhancer factor 2A | -0.0352724 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0352109 |
| TMEM123 | transmembrane protein 123 | -0.0350483 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0347701 |
| FBXO11 | F-box protein 11 | -0.0346136 |
| TPM4 | tropomyosin 4 | -0.034436 |
| RRBP1 | ribosome binding protein 1 | -0.034224 |
| ABI1 | abl-interactor 1 | -0.0340984 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0332331 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0330446 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0329808 |
| AFF4 | AF4/FMR2 family, member 4 | -0.032767 |
| BICC1 | BicC family RNA binding protein 1 | -0.0324208 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0315588 |
| FRMD5 | FERM domain containing 5 | -0.0311264 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0311213 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0310795 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0309874 |
| TJP1 | tight junction protein 1 | -0.0306947 |
