| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0304462 |
| RPS2 | ribosomal protein S2 | 0.0214233 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0186927 |
| RARA | retinoic acid receptor, alpha | 0.0153363 |
| VGF | VGF nerve growth factor inducible | 0.0137786 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0121853 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0115451 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0114338 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0111016 |
| AXL | AXL receptor tyrosine kinase | 0.00995959 |
| DHFR | dihydrofolate reductase | 0.00929672 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0092189 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00879195 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00870163 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.00869793 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.00860002 |
| PFN1 | profilin 1 | 0.00852325 |
| CCDC59 | coiled-coil domain containing 59 | 0.00850502 |
| LAMA5 | laminin, alpha 5 | 0.00847164 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00823053 |
| ZNF160 | zinc finger protein 160 | 0.0082221 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00820825 |
| MTSS2 | MTSS I-BAR domain containing 2 | 0.00813806 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00801472 |
| HEATR1 | HEAT repeat containing 1 | 0.0079959 |
| SSBP3 | single stranded DNA binding protein 3 | 0.00793582 |
| ATN1 | atrophin 1 | 0.00787393 |
| ZFP36 | ZFP36 ring finger protein | 0.00774958 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.00762017 |
| FLNA | filamin A, alpha | 0.00758923 |
| NOTCH1 | notch 1 | 0.00754634 |
| GDF15 | growth differentiation factor 15 | 0.00754533 |
| SSBP4 | single stranded DNA binding protein 4 | 0.00749798 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.00745306 |
| MT2A | metallothionein 2A | 0.00742259 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00738274 |
| DCUN1D5 | DCN1, defective in cullin neddylation 1, domain containing 5 | 0.00737638 |
| NDRG1 | N-myc downstream regulated 1 | 0.00733894 |
| POLH | polymerase (DNA directed), eta | 0.00725452 |
| GRPEL2 | GrpE-like 2, mitochondrial (E. coli) | 0.00722216 |
| BBC3 | BCL2 binding component 3 | 0.00716335 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.00714355 |
| FASN | fatty acid synthase | 0.00708981 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0070048 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | 0.00699119 |
| CWC15 | CWC15 spliceosome-associated protein | 0.00696685 |
| GASK1B | golgi associated kinase 1B | 0.00693568 |
| PODXL | podocalyxin-like | 0.00692693 |
| RPS7 | ribosomal protein S7 | 0.00692053 |
| GUK1 | guanylate kinase 1 | 0.00689914 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00677238 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00672513 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.00671417 |
| CDYL | chromodomain protein, Y-like | 0.00670044 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.00668877 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00666771 |
| C1ORF52 | chromosome 1 open reading frame 52 | 0.00663893 |
| FAM13A | family with sequence similarity 13, member A | 0.00662731 |
| METTL23 | methyltransferase like 23 | 0.00658963 |
| VEGFA | vascular endothelial growth factor A | 0.00658861 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.00658532 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00657046 |
| SERTAD2 | SERTA domain containing 2 | 0.00656669 |
| ECE1 | endothelin converting enzyme 1 | 0.00656328 |
| SLU7 | SLU7 splicing factor homolog (S. cerevisiae) | 0.00654085 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 | 0.00653725 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00653094 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00652773 |
| FAM117B | family with sequence similarity 117, member B | 0.00648973 |
| GXYLT1 | glucoside xylosyltransferase 1 | 0.00648272 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00647624 |
| COPS5 | COP9 signalosome subunit 5 | 0.00644436 |
| MYO1D | myosin ID | 0.00643975 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00640727 |
| RPF2 | ribosome production factor 2 homolog (S. cerevisiae) | 0.00639725 |
| HMG20B | high mobility group 20B | 0.00638677 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00638148 |
| RPL18A | ribosomal protein L18a | 0.00633781 |
| MASTL | microtubule associated serine/threonine kinase-like | 0.00633019 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.00632289 |
| HMGA1 | high mobility group AT-hook 1 | 0.00632214 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00631787 |
| MXD1 | MAX dimerization protein 1 | 0.00629368 |
| CAMLG | calcium modulating ligand | 0.00629271 |
| TXLNA | taxilin alpha | 0.00628838 |
| PDCD10 | programmed cell death 10 | 0.00625292 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.00624926 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00624594 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.00622934 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00621908 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.00620976 |
| CIC | capicua transcriptional repressor | 0.00620421 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.00617207 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | 0.00614204 |
| CCDC85C | coiled-coil domain containing 85C | 0.00612626 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.00611197 |
| DDA1 | DET1 and DDB1 associated 1 | 0.00610801 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00609379 |
| RIOK3 | RIO kinase 3 | 0.00609005 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.00607886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.476055 |
| LSAMP | limbic system-associated membrane protein | -0.101951 |
| VIM | vimentin | -0.0978954 |
| FMN1 | formin 1 | -0.09361 |
| SYT1 | synaptotagmin I | -0.0779921 |
| NRG1 | neuregulin 1 | -0.0750276 |
| VCL | vinculin | -0.0732255 |
| PTMA | prothymosin, alpha | -0.0725035 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0682245 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0674047 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0642016 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0634883 |
| RPL23 | ribosomal protein L23 | -0.062756 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.059024 |
| IGF2 | insulin-like growth factor 2 | -0.0585886 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0540323 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0540306 |
| TLE4 | transducin-like enhancer of split 4 | -0.0536725 |
| ACTG1 | actin gamma 1 | -0.0521735 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.051793 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0514864 |
| MEIS2 | Meis homeobox 2 | -0.0507914 |
| AHNAK | AHNAK nucleoprotein | -0.0498249 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0482071 |
| COL3A1 | collagen, type III, alpha 1 | -0.0480359 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0451934 |
| BPTF | bromodomain PHD finger transcription factor | -0.0441395 |
| PRKCA | protein kinase C, alpha | -0.043561 |
| DST | dystonin | -0.0434574 |
| UBC | ubiquitin C | -0.0422824 |
| TRIB2 | tribbles pseudokinase 2 | -0.0416893 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0416084 |
| LPIN1 | lipin 1 | -0.0415219 |
| VMP1 | vacuole membrane protein 1 | -0.0411936 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0391894 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0386326 |
| RPS27A | ribosomal protein S27a | -0.0386186 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0384104 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0382582 |
| COL1A1 | collagen, type I, alpha 1 | -0.0380671 |
| AUTS2 | autism susceptibility candidate 2 | -0.0378465 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.037441 |
| KLHL13 | kelch-like family member 13 | -0.0364775 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0353601 |
| RPL19 | ribosomal protein L19 | -0.035304 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0349889 |
| CANX | calnexin | -0.0349064 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0348692 |
| PLAT | plasminogen activator, tissue | -0.0348308 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0345905 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0342001 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0341009 |
| MAP1B | microtubule-associated protein 1B | -0.033479 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0326079 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0325643 |
| MSI2 | musashi RNA-binding protein 2 | -0.0322979 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0322257 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0321362 |
| PCBP2 | poly(rC) binding protein 2 | -0.0319874 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0314617 |
| ENAH | enabled homolog (Drosophila) | -0.0314028 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0313211 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0313164 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0310435 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0310322 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0308462 |
| ENO1 | enolase 1, (alpha) | -0.0308303 |
| RNF213 | ring finger protein 213 | -0.0303978 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0301921 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0300191 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0295592 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0295155 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0294764 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0292184 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.0292034 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0290243 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0286962 |
| PCDH9 | protocadherin 9 | -0.0286842 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0283887 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0282777 |
| MED13 | mediator complex subunit 13 | -0.0280481 |
| RPS24 | ribosomal protein S24 | -0.0276724 |
| PGK1 | phosphoglycerate kinase 1 | -0.0275799 |
| AOPEP | aminopeptidase O (putative) | -0.0275565 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0274279 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0272852 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0268177 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0266182 |
| CENPF | centromere protein F, 350/400kDa | -0.0265999 |
| APP | amyloid beta (A4) precursor protein | -0.0265767 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0265696 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0259457 |
| THBS1 | thrombospondin 1 | -0.0259196 |
| NRP1 | neuropilin 1 | -0.0257183 |
| RPLP1 | ribosomal protein, large, P1 | -0.0256554 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0253463 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0252089 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0249546 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0249075 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0247766 |
