| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF213 | ring finger protein 213 | 0.09741 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0726756 |
| VCL | vinculin | 0.0584824 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0514511 |
| RAD51B | RAD51 paralog B | 0.0477251 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0458366 |
| CPNE4 | copine IV | 0.0434564 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0432994 |
| NCKAP5 | NCK-associated protein 5 | 0.041484 |
| IFNGR1 | interferon gamma receptor 1 | 0.0404846 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0392941 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0384151 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0373721 |
| DGKH | diacylglycerol kinase, eta | 0.0361665 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0339728 |
| EXOC4 | exocyst complex component 4 | 0.0336052 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0312397 |
| USP49 | ubiquitin specific peptidase 49 | 0.0309141 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0301764 |
| SMAD3 | SMAD family member 3 | 0.0292644 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0290379 |
| SERINC5 | serine incorporator 5 | 0.0288247 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0286388 |
| DST | dystonin | 0.0286364 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0285804 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.02858 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0283173 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0277492 |
| PRKCE | protein kinase C, epsilon | 0.0273948 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0267541 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0267449 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0259781 |
| BBX | bobby sox homolog (Drosophila) | 0.0258347 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0257584 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0254134 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0253366 |
| PTGR1 | prostaglandin reductase 1 | 0.0252994 |
| MUC13 | mucin 13, cell surface associated | 0.0252757 |
| SMYD3 | SET and MYND domain containing 3 | 0.0251667 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0250698 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0249115 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.024528 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.02417 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0240556 |
| TXNRD1 | thioredoxin reductase 1 | 0.0238109 |
| ADAR | adenosine deaminase, RNA-specific | 0.0235478 |
| PSPC1 | paraspeckle component 1 | 0.0232582 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0230614 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0230467 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0230453 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0227505 |
| HDAC4 | histone deacetylase 4 | 0.0222884 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0221415 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.0219133 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0217817 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0216777 |
| PRELID2 | PRELI domain containing 2 | 0.0215472 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0212898 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0210431 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0210098 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0209792 |
| GRHL2 | grainyhead-like 2 (Drosophila) | 0.0206452 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0203637 |
| ETV6 | ets variant 6 | 0.0203474 |
| PLSCR2 | phospholipid scramblase 2 | 0.0202896 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0199641 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0198158 |
| PTK2 | protein tyrosine kinase 2 | 0.0197642 |
| SERPINA2 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) | 0.0197017 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0196097 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0194272 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0194102 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0194085 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0192594 |
| PHF3 | PHD finger protein 3 | 0.0191524 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0190345 |
| DISC1 | disrupted in schizophrenia 1 | 0.0187766 |
| CDC42SE2 | CDC42 small effector 2 | 0.0183521 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0182384 |
| GPATCH8 | G patch domain containing 8 | 0.0182253 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0181541 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.018114 |
| FRMD5 | FERM domain containing 5 | 0.0180836 |
| TBC1D4 | TBC1 domain family, member 4 | 0.0180234 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0180215 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0180051 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.017928 |
| STK24 | serine/threonine kinase 24 | 0.0177366 |
| CENPP | centromere protein P | 0.017722 |
| DIAPH3 | diaphanous-related formin 3 | 0.0177066 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0175987 |
| ADAMTS17 | ADAM metallopeptidase with thrombospondin type 1 motif, 17 | 0.01735 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0173267 |
| CLEC16A | C-type lectin domain family 16, member A | 0.0173026 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0172808 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0172555 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0172212 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0171701 |
| NAV1 | neuron navigator 1 | 0.017161 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0170651 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.187195 |
| B2M | beta-2-microglobulin | -0.15747 |
| LMO7 | LIM domain 7 | -0.148444 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.125473 |
| EGR1 | early growth response 1 | -0.0985335 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0952674 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0949392 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0939252 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0921637 |
| EZR | ezrin | -0.0913182 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.089891 |
| NDRG1 | N-myc downstream regulated 1 | -0.0856994 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.081455 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0750313 |
| SQSTM1 | sequestosome 1 | -0.0741721 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0727018 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0710354 |
| MORF4L2 | mortality factor 4 like 2 | -0.0681198 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0671597 |
| MYO1E | myosin IE | -0.065085 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0627989 |
| ANXA2 | annexin A2 | -0.0626825 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0621101 |
| INTS6 | integrator complex subunit 6 | -0.0615597 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0610077 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0607705 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0603801 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0588178 |
| CALR | calreticulin | -0.0581149 |
| COG6 | component of oligomeric golgi complex 6 | -0.0560713 |
| TRIM2 | tripartite motif containing 2 | -0.0530505 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0529281 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0528653 |
| JUN | jun proto-oncogene | -0.0524735 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0520889 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0518043 |
| TXNIP | thioredoxin interacting protein | -0.0510064 |
| HM13 | histocompatibility (minor) 13 | -0.0496832 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0495712 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0474229 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.046754 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0464867 |
| RRBP1 | ribosome binding protein 1 | -0.0449623 |
| IRF1 | interferon regulatory factor 1 | -0.0447856 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0445652 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0443144 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0441056 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0439889 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.042939 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0425526 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0420689 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0418941 |
| COPA | coatomer protein complex, subunit alpha | -0.0418929 |
| SEC24A | SEC24 family member A | -0.0415436 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0413969 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0413942 |
| TSC22D2 | TSC22 domain family, member 2 | -0.041151 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0408037 |
| SPAG9 | sperm associated antigen 9 | -0.0404039 |
| GOLGB1 | golgin B1 | -0.0402987 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0398533 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0398409 |
| UBC | ubiquitin C | -0.0395507 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0393183 |
| HDLBP | high density lipoprotein binding protein | -0.0392245 |
| ITGA6 | integrin, alpha 6 | -0.0389913 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0387194 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0385357 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0380683 |
| ADIPOR2 | adiponectin receptor 2 | -0.0378947 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0375001 |
| WDR45B | WD repeat domain 45B | -0.0373922 |
| GOLGA2 | golgin A2 | -0.0371308 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0368766 |
| TMC5 | transmembrane channel-like 5 | -0.036851 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0365568 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0363482 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0361416 |
| ARF4 | ADP-ribosylation factor 4 | -0.0359338 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0356937 |
| AGR2 | anterior gradient 2 | -0.0356798 |
| CALU | calumenin | -0.0356062 |
| SEC24D | SEC24 family member D | -0.0351621 |
| HLA-B | major histocompatibility complex, class I, B | -0.0348252 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0348204 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0345187 |
| ANXA1 | annexin A1 | -0.0340701 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0334811 |
| PERP | PERP, TP53 apoptosis effector | -0.0330447 |
| MT2A | metallothionein 2A | -0.0328726 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0321705 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0321487 |
| PKM | pyruvate kinase, muscle | -0.0321468 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0319584 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0318457 |
| TMEM263 | transmembrane protein 263 | -0.0312747 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0310259 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0310031 |
| FTL | ferritin, light polypeptide | -0.0306612 |
| CDHR2 | cadherin-related family member 2 | -0.0305902 |
