| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.098331 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0669479 |
| RPS2 | ribosomal protein S2 | 0.0578709 |
| YBX1 | Y box binding protein 1 | 0.0486233 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0459092 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0442616 |
| GOLGA4 | golgin A4 | 0.0420886 |
| RPS6 | ribosomal protein S6 | 0.0402672 |
| GDF15 | growth differentiation factor 15 | 0.0390021 |
| TPI1 | triosephosphate isomerase 1 | 0.0368522 |
| STC1 | stanniocalcin 1 | 0.036024 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0342348 |
| YBX3 | Y box binding protein 3 | 0.033374 |
| SFXN1 | sideroflexin 1 | 0.0290646 |
| SMAD3 | SMAD family member 3 | 0.0285505 |
| RAI1 | retinoic acid induced 1 | 0.0283875 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0270396 |
| EGR1 | early growth response 1 | 0.025246 |
| TUBA1B | tubulin, alpha 1b | 0.0252384 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0251998 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0249893 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0248592 |
| FNBP1 | formin binding protein 1 | 0.0247352 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0239154 |
| VEGFC | vascular endothelial growth factor C | 0.023738 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0236407 |
| RNF24 | ring finger protein 24 | 0.0234855 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0234361 |
| RPL36 | ribosomal protein L36 | 0.0233051 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0222635 |
| RPL32 | ribosomal protein L32 | 0.0221919 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0220762 |
| RPS19 | ribosomal protein S19 | 0.0219602 |
| RPL35 | ribosomal protein L35 | 0.0218303 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.0213959 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.021291 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0212239 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0210234 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0205038 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | 0.0203482 |
| RPS4X | ribosomal protein S4, X-linked | 0.0202918 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0195613 |
| RPL4 | ribosomal protein L4 | 0.0195395 |
| SYAP1 | synapse associated protein 1 | 0.0192432 |
| LMNA | lamin A/C | 0.019182 |
| MXI1 | MAX interactor 1, dimerization protein | 0.019127 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.0190732 |
| FAM13A | family with sequence similarity 13, member A | 0.0190268 |
| GOLGA2 | golgin A2 | 0.0190095 |
| PHF21A | PHD finger protein 21A | 0.0188093 |
| RPL8 | ribosomal protein L8 | 0.018752 |
| GNAS | GNAS complex locus | 0.018659 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0186488 |
| ZNF106 | zinc finger protein 106 | 0.0186367 |
| MYADM | myeloid-associated differentiation marker | 0.0184881 |
| CLU | clusterin | 0.0184713 |
| RPL28 | ribosomal protein L28 | 0.0184511 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0183832 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0181857 |
| GOLT1B | golgi transport 1B | 0.0178747 |
| TLN1 | talin 1 | 0.0178715 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0176902 |
| CCDC14 | coiled-coil domain containing 14 | 0.0176355 |
| MT1X | metallothionein 1X | 0.0175186 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.0174927 |
| TRIM24 | tripartite motif containing 24 | 0.0173771 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0173696 |
| AXL | AXL receptor tyrosine kinase | 0.0172313 |
| PFN1 | profilin 1 | 0.0172192 |
| EPAS1 | endothelial PAS domain protein 1 | 0.017205 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0169581 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0169364 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0166781 |
| CD99 | CD99 molecule | 0.0166635 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0166147 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0165622 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 | 0.0164363 |
| CREBBP | CREB binding protein | 0.0164325 |
| RACK1 | receptor for activated C kinase 1 | 0.016273 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.0162315 |
| SMAP2 | small ArfGAP2 | 0.0161978 |
| CDK19 | cyclin-dependent kinase 19 | 0.0161263 |
| ARF1 | ADP-ribosylation factor 1 | 0.0160518 |
| HSPB11 | heat shock protein family B (small), member 11 | 0.0160491 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | 0.0158989 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0158216 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.0158009 |
| TMF1 | TATA element modulatory factor 1 | 0.0157594 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0155783 |
| CADM1 | cell adhesion molecule 1 | 0.0154791 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0154146 |
| RAB13 | RAB13, member RAS oncogene family | 0.0152211 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0151686 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0151509 |
| TMSB4X | thymosin beta 4, X-linked | 0.0150963 |
| CCNL1 | cyclin L1 | 0.0150956 |
| RPL18 | ribosomal protein L18 | 0.0149734 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0148361 |
| ELL | elongation factor RNA polymerase II | 0.0147933 |
| SERF2 | small EDRK-rich factor 2 | 0.0147866 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.167646 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.133155 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.117566 |
| HLA-B | major histocompatibility complex, class I, B | -0.109442 |
| COL6A3 | collagen, type VI, alpha 3 | -0.101587 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0935227 |
| VIM | vimentin | -0.0900253 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0889541 |
| CD44 | CD44 molecule (Indian blood group) | -0.0878684 |
| TMSB10 | thymosin beta 10 | -0.0823044 |
| FN1 | fibronectin 1 | -0.0815914 |
| B2M | beta-2-microglobulin | -0.0807433 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0769295 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0757367 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0732126 |
| AHNAK | AHNAK nucleoprotein | -0.0714215 |
| TPM4 | tropomyosin 4 | -0.0708491 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0700984 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0676569 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0674532 |
| PKM | pyruvate kinase, muscle | -0.0669117 |
| UBC | ubiquitin C | -0.0661108 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0656402 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0652439 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0639058 |
| RPL23 | ribosomal protein L23 | -0.0603999 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0603353 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0577551 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0548908 |
| PTK2 | protein tyrosine kinase 2 | -0.0527883 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0526909 |
| IGF2 | insulin-like growth factor 2 | -0.0523244 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0523224 |
| LDHA | lactate dehydrogenase A | -0.0516717 |
| CANX | calnexin | -0.0511728 |
| CALR | calreticulin | -0.0506183 |
| KYNU | kynureninase | -0.0502267 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0476705 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0473818 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0468833 |
| RPS27A | ribosomal protein S27a | -0.0461899 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0460978 |
| BPTF | bromodomain PHD finger transcription factor | -0.0460886 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.044745 |
| ENO1 | enolase 1, (alpha) | -0.0437741 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0434869 |
| VCL | vinculin | -0.0433046 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0432603 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0432288 |
| HDAC9 | histone deacetylase 9 | -0.0430699 |
| POTEF | POTE ankyrin domain family, member F | -0.0429879 |
| HIP1 | huntingtin interacting protein 1 | -0.0418146 |
| ACTG1 | actin gamma 1 | -0.0418124 |
| ASPH | aspartate beta-hydroxylase | -0.0415794 |
| GLIS3 | GLIS family zinc finger 3 | -0.0409509 |
| APP | amyloid beta (A4) precursor protein | -0.0406942 |
| HLA-A | major histocompatibility complex, class I, A | -0.0404927 |
| USP34 | ubiquitin specific peptidase 34 | -0.0404567 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0399702 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0398614 |
| INTS6 | integrator complex subunit 6 | -0.0398045 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0396863 |
| FBXO11 | F-box protein 11 | -0.0379744 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0377776 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0374934 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0369032 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0363744 |
| SRP54 | signal recognition particle 54kDa | -0.0361035 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0359233 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0358381 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0354943 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0348315 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0345232 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0341316 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0340569 |
| RPL37A | ribosomal protein L37a | -0.0340136 |
| DIAPH2 | diaphanous-related formin 2 | -0.0338251 |
| RUNX1 | runt-related transcription factor 1 | -0.033541 |
| PGK1 | phosphoglycerate kinase 1 | -0.0333032 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0331994 |
| NAV1 | neuron navigator 1 | -0.0330088 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0326954 |
| CALD1 | caldesmon 1 | -0.0326009 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.032527 |
| CLIC4 | chloride intracellular channel 4 | -0.0324732 |
| RNF216 | ring finger protein 216 | -0.0323176 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.032201 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0321858 |
| COPA | coatomer protein complex, subunit alpha | -0.0318337 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0317523 |
| CLMP | CXADR-like membrane protein | -0.0315236 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0314007 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0311739 |
| LMAN1 | lectin, mannose-binding, 1 | -0.030719 |
| RPL19 | ribosomal protein L19 | -0.0304661 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0304036 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.030402 |
| ADM | adrenomedullin | -0.0302511 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0301449 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0299591 |
