| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.100418 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0961615 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0877042 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0688708 |
| PRELID2 | PRELI domain containing 2 | 0.0596447 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0546359 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0537198 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.05222 |
| GOLGA4 | golgin A4 | 0.0492489 |
| RPS2 | ribosomal protein S2 | 0.0446694 |
| RAD51B | RAD51 paralog B | 0.043177 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0410609 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0381279 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0349798 |
| TXNRD1 | thioredoxin reductase 1 | 0.0341271 |
| RPL4 | ribosomal protein L4 | 0.0336569 |
| FAM117B | family with sequence similarity 117, member B | 0.0335471 |
| NUP58 | nucleoporin 58 | 0.0319489 |
| RPS6 | ribosomal protein S6 | 0.0317746 |
| PCBP2 | poly(rC) binding protein 2 | 0.0315943 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0309621 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0302242 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0301307 |
| KIAA1217 | KIAA1217 | 0.0295616 |
| HELZ | helicase with zinc finger | 0.0290819 |
| YEATS2 | YEATS domain containing 2 | 0.0290453 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.02863 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0284318 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.027871 |
| DIAPH3 | diaphanous-related formin 3 | 0.0277027 |
| OGA | O-GlcNAcase | 0.02762 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0274614 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0271583 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0270379 |
| SFXN1 | sideroflexin 1 | 0.0267878 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.02662 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0260861 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0256136 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0254976 |
| SEC24D | SEC24 family member D | 0.0254631 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0250697 |
| RUNX1 | runt-related transcription factor 1 | 0.0247075 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0246828 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0243453 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0242364 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.024202 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.023612 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0235206 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0234706 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0233769 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0233051 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.023197 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.023171 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0228758 |
| USP37 | ubiquitin specific peptidase 37 | 0.0227744 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0227372 |
| SUCO | SUN domain containing ossification factor | 0.022601 |
| RIOK3 | RIO kinase 3 | 0.0225487 |
| SETD5 | SET domain containing 5 | 0.0224567 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0220467 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0218719 |
| RBM39 | RNA binding motif protein 39 | 0.021495 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0213062 |
| TPR | translocated promoter region, nuclear basket protein | 0.0212729 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0212569 |
| COG5 | component of oligomeric golgi complex 5 | 0.0212362 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0210259 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.02101 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0209106 |
| NBAS | neuroblastoma amplified sequence | 0.0208179 |
| INSIG2 | insulin induced gene 2 | 0.0208004 |
| RNF24 | ring finger protein 24 | 0.0206878 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0200367 |
| CCNG2 | cyclin G2 | 0.0199984 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0199809 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0199523 |
| TLN1 | talin 1 | 0.0197028 |
| ZNF654 | zinc finger protein 654 | 0.0197001 |
| PER1 | period circadian clock 1 | 0.0196926 |
| MYO1B | myosin IB | 0.0196801 |
| LNPK | lunapark, ER junction formation factor | 0.0196355 |
| COG6 | component of oligomeric golgi complex 6 | 0.0194141 |
| ATXN2L | ataxin 2-like | 0.0194133 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.019198 |
| ZNF292 | zinc finger protein 292 | 0.0189201 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0189108 |
| BRD4 | bromodomain containing 4 | 0.0187884 |
| GOLGA2 | golgin A2 | 0.0187446 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0186266 |
| MED15 | mediator complex subunit 15 | 0.0185268 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0182771 |
| CEP57 | centrosomal protein 57kDa | 0.0181851 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0181511 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0181494 |
| MATR3 | matrin 3 | 0.0180623 |
| TPM3 | tropomyosin 3 | 0.0179334 |
| SRP54 | signal recognition particle 54kDa | 0.0178884 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0177976 |
| PAPOLA | poly(A) polymerase alpha | 0.0177601 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.017725 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | -0.240786 |
| PTMA | prothymosin, alpha | -0.213093 |
| TMSB10 | thymosin beta 10 | -0.140306 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.131632 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.105458 |
| AHNAK | AHNAK nucleoprotein | -0.101433 |
| EGR1 | early growth response 1 | -0.0811733 |
| EZR | ezrin | -0.074971 |
| NDRG1 | N-myc downstream regulated 1 | -0.0726314 |
| TPM4 | tropomyosin 4 | -0.0675648 |
| MT2A | metallothionein 2A | -0.0625619 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0615601 |
| ACTG1 | actin gamma 1 | -0.0557439 |
| KRT18 | keratin 18, type I | -0.0529975 |
| MCL1 | myeloid cell leukemia 1 | -0.0476574 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0476053 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0471615 |
| RPL35A | ribosomal protein L35a | -0.0465598 |
| SERINC5 | serine incorporator 5 | -0.0459891 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0451749 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0443565 |
| VCL | vinculin | -0.0436138 |
| ARF4 | ADP-ribosylation factor 4 | -0.042403 |
| EPCAM | epithelial cell adhesion molecule | -0.0418211 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0404514 |
| ACTN4 | actinin, alpha 4 | -0.0401129 |
| S100A10 | S100 calcium binding protein A10 | -0.0389231 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0386392 |
| JUN | jun proto-oncogene | -0.0361942 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0360986 |
| KRT19 | keratin 19, type I | -0.0352901 |
| POTEF | POTE ankyrin domain family, member F | -0.0349416 |
| HMGA1 | high mobility group AT-hook 1 | -0.0338999 |
| TENM3 | teneurin transmembrane protein 3 | -0.0333489 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0332185 |
| MKI67 | marker of proliferation Ki-67 | -0.0331224 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.032862 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0328577 |
| CCND1 | cyclin D1 | -0.0324876 |
| PKM | pyruvate kinase, muscle | -0.0323923 |
| RPS24 | ribosomal protein S24 | -0.0314719 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.031116 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0309698 |
| KLF6 | Kruppel-like factor 6 | -0.0307663 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0304258 |
| S100A6 | S100 calcium binding protein A6 | -0.030234 |
| HMGA2 | high mobility group AT-hook 2 | -0.0302264 |
| RPL34 | ribosomal protein L34 | -0.0299152 |
| RPS8 | ribosomal protein S8 | -0.0295489 |
| RPS13 | ribosomal protein S13 | -0.0290342 |
| DIAPH2 | diaphanous-related formin 2 | -0.0288795 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0287665 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0286785 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0279351 |
| RPLP1 | ribosomal protein, large, P1 | -0.0271557 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0270272 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0268301 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0263181 |
| CD2AP | CD2-associated protein | -0.0258162 |
| RPLP0 | ribosomal protein, large, P0 | -0.0258035 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0256334 |
| BPTF | bromodomain PHD finger transcription factor | -0.0251263 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0250962 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0249236 |
| CBX3 | chromobox homolog 3 | -0.0247643 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0243111 |
| SBF2 | SET binding factor 2 | -0.0241875 |
| MYO1E | myosin IE | -0.0241007 |
| S100A9 | S100 calcium binding protein A9 | -0.0240871 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0240481 |
| MED13 | mediator complex subunit 13 | -0.0234578 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0234505 |
| FRMD5 | FERM domain containing 5 | -0.0232589 |
| ZFHX3 | zinc finger homeobox 3 | -0.0229611 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0224582 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0222977 |
| KRT8 | keratin 8, type II | -0.0222859 |
| PFN1 | profilin 1 | -0.022173 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0221272 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0220067 |
| HMGB1 | high mobility group box 1 | -0.0218653 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0215544 |
| ENO1 | enolase 1, (alpha) | -0.021547 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0214635 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0214269 |
| RHOA | ras homolog family member A | -0.0213268 |
| RPL31 | ribosomal protein L31 | -0.0212081 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0211885 |
| MSI2 | musashi RNA-binding protein 2 | -0.0210382 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0210289 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0209135 |
| CENPF | centromere protein F, 350/400kDa | -0.0208824 |
| WWC1 | WW and C2 domain containing 1 | -0.0208545 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0207279 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0203331 |
| RPS25 | ribosomal protein S25 | -0.0202055 |
| GPHN | gephyrin | -0.0201862 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0201166 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0200822 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0199083 |
