| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Epirubicin (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0558195 |
| RPS2 | ribosomal protein S2 | 0.0373534 |
| TUBA1B | tubulin, alpha 1b | 0.0200135 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0197518 |
| TPM3 | tropomyosin 3 | 0.0187527 |
| FLNA | filamin A, alpha | 0.0179911 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0175956 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0165612 |
| RPL4 | ribosomal protein L4 | 0.0165605 |
| PNN | pinin, desmosome associated protein | 0.0163305 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0151505 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0146598 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0141978 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.014143 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0139317 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0138488 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.01383 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0136492 |
| RPS6 | ribosomal protein S6 | 0.0134906 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0130083 |
| CCNL1 | cyclin L1 | 0.0126814 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0122358 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0117902 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0117506 |
| CCNT2 | cyclin T2 | 0.0116994 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0112076 |
| HDGF | hepatoma-derived growth factor | 0.0111362 |
| DHFR | dihydrofolate reductase | 0.0110485 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0108575 |
| RPL21 | ribosomal protein L21 | 0.0107392 |
| BRD4 | bromodomain containing 4 | 0.0106687 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0105523 |
| RPS7 | ribosomal protein S7 | 0.010359 |
| HMGB2 | high mobility group box 2 | 0.0102548 |
| TLN1 | talin 1 | 0.0101801 |
| TMF1 | TATA element modulatory factor 1 | 0.0101075 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.00991496 |
| SNX2 | sorting nexin 2 | 0.00991271 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.009833 |
| VEGFA | vascular endothelial growth factor A | 0.00959826 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0095527 |
| CAMLG | calcium modulating ligand | 0.00952261 |
| RPL3 | ribosomal protein L3 | 0.00945469 |
| RPS12 | ribosomal protein S12 | 0.00934101 |
| PCBP2 | poly(rC) binding protein 2 | 0.00919142 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.00914792 |
| RNF145 | ring finger protein 145 | 0.00913678 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00902332 |
| H1-4 | H1.4 linker histone, cluster member | 0.00901391 |
| WDR43 | WD repeat domain 43 | 0.00886591 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00838834 |
| FAM13A | family with sequence similarity 13, member A | 0.00828944 |
| HCFC1 | host cell factor C1 | 0.00826627 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) | 0.00815783 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00814922 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00811624 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00795558 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00783905 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0077428 |
| FOXM1 | forkhead box M1 | 0.00766554 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00763886 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.00760125 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.00758288 |
| ATN1 | atrophin 1 | 0.00752778 |
| RBM26 | RNA binding motif protein 26 | 0.00752758 |
| CREBRF | CREB3 regulatory factor | 0.00746956 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0074127 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00733971 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0073079 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.00715801 |
| RPS3A | ribosomal protein S3A | 0.00715654 |
| UCK2 | uridine-cytidine kinase 2 | 0.00714888 |
| EEF2K | eukaryotic elongation factor 2 kinase | 0.00711462 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.00701789 |
| PRPF4B | pre-mRNA processing factor 4B | 0.00700764 |
| SECISBP2L | SECIS binding protein 2-like | 0.00699375 |
| AXL | AXL receptor tyrosine kinase | 0.00687798 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0068548 |
| REST | RE1-silencing transcription factor | 0.00683125 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00679696 |
| BICRA | BRD4 interacting chromatin remodeling complex associated protein | 0.00677856 |
| HSPA4 | heat shock 70kDa protein 4 | 0.00675884 |
| SCAMP2 | secretory carrier membrane protein 2 | 0.00669089 |
| RPS18 | ribosomal protein S18 | 0.00666274 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.00666002 |
| TBC1D12 | TBC1 domain family, member 12 | 0.00660968 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00658763 |
| PRPF8 | pre-mRNA processing factor 8 | 0.00658259 |
| STC1 | stanniocalcin 1 | 0.00654025 |
| PSMG2 | proteasome (prosome, macropain) assembly chaperone 2 | 0.00650099 |
| CIP2A | cellular inhibitor of PP2A | 0.00648572 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.00646949 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.00645705 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 0.00645337 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.00642428 |
| ABHD14B | abhydrolase domain containing 14B | 0.00641033 |
| RANBP1 | RAN binding protein 1 | 0.00640027 |
| EXOSC10 | exosome component 10 | 0.00636737 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.00635357 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | 0.00632792 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | -0.132541 |
| ASPH | aspartate beta-hydroxylase | -0.109217 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.10861 |
| MT2A | metallothionein 2A | -0.105249 |
| TMSB10 | thymosin beta 10 | -0.10207 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100916 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.091822 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0910387 |
| RPL35A | ribosomal protein L35a | -0.0891933 |
| CCND1 | cyclin D1 | -0.0859857 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0831271 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0763222 |
| LDHA | lactate dehydrogenase A | -0.0743893 |
| FTL | ferritin, light polypeptide | -0.0743715 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0707926 |
| PRELID2 | PRELI domain containing 2 | -0.0707279 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0663708 |
| ENO1 | enolase 1, (alpha) | -0.065872 |
| AHNAK | AHNAK nucleoprotein | -0.0627475 |
| PAX8 | paired box 8 | -0.0615999 |
| ITGB8 | integrin, beta 8 | -0.0590923 |
| RPLP1 | ribosomal protein, large, P1 | -0.0573911 |
| VCL | vinculin | -0.0559285 |
| PKM | pyruvate kinase, muscle | -0.0549214 |
| ACTN4 | actinin, alpha 4 | -0.0546277 |
| TPM4 | tropomyosin 4 | -0.0544746 |
| RPL31 | ribosomal protein L31 | -0.0542383 |
| RPL23 | ribosomal protein L23 | -0.0539289 |
| RPL19 | ribosomal protein L19 | -0.0529353 |
| TXNRD1 | thioredoxin reductase 1 | -0.0524447 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0521468 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0520033 |
| MACROD2 | MACRO domain containing 2 | -0.0508361 |
| APP | amyloid beta (A4) precursor protein | -0.0504649 |
| S100A10 | S100 calcium binding protein A10 | -0.0503606 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0502715 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0473987 |
| NF1 | neurofibromin 1 | -0.0472209 |
| SSH2 | slingshot protein phosphatase 2 | -0.0467673 |
| FLNB | filamin B, beta | -0.0459103 |
| PGK1 | phosphoglycerate kinase 1 | -0.0458877 |
| B2M | beta-2-microglobulin | -0.0452885 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0443862 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0436775 |
| ANXA2 | annexin A2 | -0.0436561 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0429872 |
| POTEF | POTE ankyrin domain family, member F | -0.0428244 |
| SEPTIN7 | septin 7 | -0.0425092 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0422514 |
| RPLP0 | ribosomal protein, large, P0 | -0.0422012 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0421326 |
| RPL12 | ribosomal protein L12 | -0.0419114 |
| SMYD3 | SET and MYND domain containing 3 | -0.0413675 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.041325 |
| CD44 | CD44 molecule (Indian blood group) | -0.0405464 |
| KRT7 | keratin 7, type II | -0.0396322 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0385026 |
| CANX | calnexin | -0.0370972 |
| BPTF | bromodomain PHD finger transcription factor | -0.0369153 |
| RAD51B | RAD51 paralog B | -0.0368668 |
| RPS24 | ribosomal protein S24 | -0.0366309 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0365592 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.035945 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0357126 |
| FHIT | fragile histidine triad | -0.035598 |
| RPL34 | ribosomal protein L34 | -0.0355254 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.035044 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0343037 |
| RPS8 | ribosomal protein S8 | -0.0342875 |
| S100A6 | S100 calcium binding protein A6 | -0.034285 |
| PTMA | prothymosin, alpha | -0.0342131 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0339678 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0337919 |
| ATXN1 | ataxin 1 | -0.0336917 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0333233 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0332351 |
| TMSB4X | thymosin beta 4, X-linked | -0.0330408 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0327855 |
| MT1X | metallothionein 1X | -0.0324483 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0322695 |
| RPL11 | ribosomal protein L11 | -0.032249 |
| RPL32 | ribosomal protein L32 | -0.0321788 |
| SVIL | supervillin | -0.0321762 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0321432 |
| DEK | DEK proto-oncogene | -0.0318637 |
| WWC1 | WW and C2 domain containing 1 | -0.0311263 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0310815 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0309994 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0307665 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0307627 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.030642 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0296205 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.029574 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0290042 |
| HMGA2 | high mobility group AT-hook 2 | -0.0289857 |
| RPS19 | ribosomal protein S19 | -0.0289685 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0289454 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.028937 |
| ERBIN | erbb2 interacting protein | -0.0285858 |
| CDCP1 | CUB domain containing protein 1 | -0.0285323 |
