| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.223548 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0463194 |
| VCL | vinculin | 0.0434558 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0303169 |
| FLNA | filamin A, alpha | 0.0292465 |
| RPS2 | ribosomal protein S2 | 0.0279607 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0257189 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0255781 |
| RPS6 | ribosomal protein S6 | 0.0252812 |
| RPL4 | ribosomal protein L4 | 0.0233941 |
| MT2A | metallothionein 2A | 0.0221474 |
| RPS12 | ribosomal protein S12 | 0.021988 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0217139 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.021231 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.020399 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0203247 |
| RPS8 | ribosomal protein S8 | 0.0195342 |
| TPI1 | triosephosphate isomerase 1 | 0.0189556 |
| RPL37A | ribosomal protein L37a | 0.018696 |
| RPL12 | ribosomal protein L12 | 0.0171789 |
| RPL26 | ribosomal protein L26 | 0.0170215 |
| RPS17 | ribosomal protein S17 | 0.0166249 |
| RPS19 | ribosomal protein S19 | 0.0163926 |
| EGR1 | early growth response 1 | 0.0162349 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0159414 |
| RPLP2 | ribosomal protein, large, P2 | 0.0153841 |
| RPS3 | ribosomal protein S3 | 0.0152035 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0150411 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0148294 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0148261 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0146148 |
| RACK1 | receptor for activated C kinase 1 | 0.014612 |
| WWOX | WW domain containing oxidoreductase | 0.0145162 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0144734 |
| RPS16 | ribosomal protein S16 | 0.0142848 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0142417 |
| NABP1 | nucleic acid binding protein 1 | 0.0139538 |
| SHISA5 | shisa family member 5 | 0.0137506 |
| RPL32 | ribosomal protein L32 | 0.0137224 |
| SLC25A51 | solute carrier family 25, member 51 | 0.0135864 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0135057 |
| HMGB2 | high mobility group box 2 | 0.0134097 |
| CAPRIN2 | caprin family member 2 | 0.013002 |
| CLIC4 | chloride intracellular channel 4 | 0.0128748 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 0.0128626 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0128015 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.012533 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0125086 |
| PALLD | palladin, cytoskeletal associated protein | 0.0124514 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0121095 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0116884 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0113356 |
| RPL27 | ribosomal protein L27 | 0.0111102 |
| RPL9 | ribosomal protein L9 | 0.0110389 |
| H1-4 | H1.4 linker histone, cluster member | 0.0107931 |
| RPS27A | ribosomal protein S27a | 0.0107465 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0105602 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0104897 |
| RPL28 | ribosomal protein L28 | 0.0104347 |
| PODXL | podocalyxin-like | 0.0103142 |
| RPL11 | ribosomal protein L11 | 0.0101824 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0100797 |
| FTL | ferritin, light polypeptide | 0.0100787 |
| IPO9 | importin 9 | 0.0100614 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0100068 |
| IPO7 | importin 7 | 0.00987416 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00977951 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00967978 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.00957923 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.009543 |
| RPL34 | ribosomal protein L34 | 0.00949987 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0093874 |
| RCOR1 | REST corepressor 1 | 0.00924278 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.009212 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.00915645 |
| RPL13A | ribosomal protein L13a | 0.00907192 |
| RPL14 | ribosomal protein L14 | 0.00899247 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00898536 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00892674 |
| TOP1 | topoisomerase (DNA) I | 0.00864284 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.00857125 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0085283 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | 0.00851697 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.00843709 |
| THBS1 | thrombospondin 1 | 0.00843517 |
| PNN | pinin, desmosome associated protein | 0.008373 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.00817015 |
| FHL2 | four and a half LIM domains 2 | 0.00811242 |
| TTC23L | tetratricopeptide repeat domain 23-like | 0.00804099 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00794069 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00790589 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.00790433 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00788367 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.00788009 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.00785362 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00784287 |
| DGKI | diacylglycerol kinase, iota | 0.00769499 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00766857 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00765333 |
| RPS10 | ribosomal protein S10 | 0.00765047 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.358512 |
| VIM | vimentin | -0.276173 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.216799 |
| IGF2 | insulin-like growth factor 2 | -0.171448 |
| NDRG1 | N-myc downstream regulated 1 | -0.159434 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.134002 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.127107 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.121305 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.11958 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.118241 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.098712 |
| FAM13A | family with sequence similarity 13, member A | -0.0844231 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0829328 |
| RAI14 | retinoic acid induced 14 | -0.080801 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0807328 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0798289 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0774933 |
| CDH13 | cadherin 13 | -0.0770559 |
| MYO10 | myosin X | -0.0747763 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0706054 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0689708 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.067661 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.067524 |
| PGK1 | phosphoglycerate kinase 1 | -0.0656524 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0653352 |
| NGLY1 | N-glycanase 1 | -0.0643002 |
| PDE10A | phosphodiesterase 10A | -0.0641048 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0626336 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0623192 |
| COL5A1 | collagen, type V, alpha 1 | -0.0610736 |
| TENM2 | teneurin transmembrane protein 2 | -0.0579321 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0571287 |
| SBF2 | SET binding factor 2 | -0.0569477 |
| RUNX1 | runt-related transcription factor 1 | -0.0560968 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0535531 |
| USP34 | ubiquitin specific peptidase 34 | -0.0532046 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0530243 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0514483 |
| FLNB | filamin B, beta | -0.0508387 |
| COPA | coatomer protein complex, subunit alpha | -0.0508376 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0488882 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0487903 |
| CD109 | CD109 molecule | -0.0484453 |
| ADM | adrenomedullin | -0.0482558 |
| SETD5 | SET domain containing 5 | -0.0480083 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0472259 |
| TMEM165 | transmembrane protein 165 | -0.0465563 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0460389 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0459478 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0457577 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0454318 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0452393 |
| MMP12 | matrix metallopeptidase 12 | -0.0447924 |
| CANX | calnexin | -0.0438089 |
| PTK2 | protein tyrosine kinase 2 | -0.0436755 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0434319 |
| RNF24 | ring finger protein 24 | -0.0431634 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0430199 |
| INSIG2 | insulin induced gene 2 | -0.042859 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0424986 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0423035 |
| DST | dystonin | -0.0422696 |
| NF1 | neurofibromin 1 | -0.0421869 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0421643 |
| SEC24A | SEC24 family member A | -0.0417009 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0416264 |
| ANXA2 | annexin A2 | -0.0415181 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0414655 |
| HMGA2 | high mobility group AT-hook 2 | -0.0403721 |
| CLMP | CXADR-like membrane protein | -0.0403464 |
| CALU | calumenin | -0.040081 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0400057 |
| TMSB10 | thymosin beta 10 | -0.0393237 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0391768 |
| GLIS3 | GLIS family zinc finger 3 | -0.0387707 |
| LOX | lysyl oxidase | -0.0382652 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0381943 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0376454 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0375108 |
| GOLGA4 | golgin A4 | -0.0374083 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0371568 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0370476 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0367216 |
| MORF4L2 | mortality factor 4 like 2 | -0.0364085 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.036404 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0362707 |
| DIAPH2 | diaphanous-related formin 2 | -0.0361361 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0354008 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0352351 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0350864 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0349349 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0349178 |
| RASA3 | RAS p21 protein activator 3 | -0.034889 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0342649 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0341937 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0341141 |
| FMN1 | formin 1 | -0.0336318 |
| LAMB3 | laminin, beta 3 | -0.0328448 |
| MAP4 | microtubule-associated protein 4 | -0.0327869 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0326175 |
