| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0606483 |
| EGFR | epidermal growth factor receptor | 0.0523166 |
| CDH13 | cadherin 13 | 0.0522503 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0510776 |
| RPS6 | ribosomal protein S6 | 0.0443828 |
| EFNA5 | ephrin-A5 | 0.0418718 |
| STC1 | stanniocalcin 1 | 0.0410029 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0334773 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0313838 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0301784 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0286215 |
| STC2 | stanniocalcin 2 | 0.0275857 |
| FLNA | filamin A, alpha | 0.0274016 |
| CADM1 | cell adhesion molecule 1 | 0.027279 |
| RPS2 | ribosomal protein S2 | 0.026388 |
| RUNX1 | runt-related transcription factor 1 | 0.0259488 |
| AXL | AXL receptor tyrosine kinase | 0.0251242 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0238675 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0236778 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0231402 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0222722 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0222606 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0222355 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0214549 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0201605 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0200462 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0191397 |
| CLMP | CXADR-like membrane protein | 0.0190101 |
| CA12 | carbonic anhydrase XII | 0.0187303 |
| CCNL1 | cyclin L1 | 0.0185569 |
| DTNA | dystrobrevin, alpha | 0.0182388 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0181854 |
| TPI1 | triosephosphate isomerase 1 | 0.0180076 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0179079 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0178076 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0178014 |
| HMGA2 | high mobility group AT-hook 2 | 0.017465 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0173883 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0173644 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0172367 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0169655 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0169501 |
| RAD51B | RAD51 paralog B | 0.0168644 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0168474 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0164447 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0164038 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0161498 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0156965 |
| RPL4 | ribosomal protein L4 | 0.0144461 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0144299 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0142181 |
| ECE1 | endothelin converting enzyme 1 | 0.0139776 |
| RIN2 | Ras and Rab interactor 2 | 0.013786 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.01372 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0136111 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0134861 |
| IL6 | interleukin 6 | 0.0133607 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0133305 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0132471 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0129442 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.012917 |
| XYLT1 | xylosyltransferase I | 0.0128548 |
| RPS12 | ribosomal protein S12 | 0.0128118 |
| NAV2 | neuron navigator 2 | 0.0127275 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0124643 |
| FAM219A | family with sequence similarity 219, member A | 0.0123793 |
| MYO10 | myosin X | 0.0123415 |
| SMAD3 | SMAD family member 3 | 0.0122499 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0122399 |
| LOX | lysyl oxidase | 0.0122043 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0121925 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0120248 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0119368 |
| NBAS | neuroblastoma amplified sequence | 0.0119014 |
| KIAA1549L | KIAA1549-like | 0.0118262 |
| EXOC4 | exocyst complex component 4 | 0.0117156 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0116481 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0116353 |
| PRR16 | proline rich 16 | 0.0115175 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0114999 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0114636 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0113554 |
| TMF1 | TATA element modulatory factor 1 | 0.0112521 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0111077 |
| TLN1 | talin 1 | 0.0110616 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0109568 |
| OXR1 | oxidation resistance 1 | 0.0106567 |
| DENND1A | DENN/MADD domain containing 1A | 0.0106321 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0106149 |
| BRD2 | bromodomain containing 2 | 0.0106007 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0104248 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0103418 |
| SESN2 | sestrin 2 | 0.0103303 |
| LAMB3 | laminin, beta 3 | 0.0103172 |
| YEATS2 | YEATS domain containing 2 | 0.010313 |
| HELZ | helicase with zinc finger | 0.0102696 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0102565 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0102299 |
| RPL37A | ribosomal protein L37a | 0.0102207 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0102142 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.513376 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.266833 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.199736 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112449 |
| COL6A3 | collagen, type VI, alpha 3 | -0.111258 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.10434 |
| CD44 | CD44 molecule (Indian blood group) | -0.0990278 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0660465 |
| MT2A | metallothionein 2A | -0.0649365 |
| VIM | vimentin | -0.0626678 |
| TPM4 | tropomyosin 4 | -0.0593791 |
| COL1A2 | collagen, type I, alpha 2 | -0.0561194 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0496223 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0495353 |
| LDHA | lactate dehydrogenase A | -0.0484138 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0470199 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.045287 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0444933 |
| TMSB10 | thymosin beta 10 | -0.0438498 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0433002 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.043275 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0431189 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0429126 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0426797 |
| COL1A1 | collagen, type I, alpha 1 | -0.0421614 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0409332 |
| AHNAK | AHNAK nucleoprotein | -0.0406129 |
| VCL | vinculin | -0.0394893 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0394684 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0377024 |
| OSMR | oncostatin M receptor | -0.0375749 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0368604 |
| POSTN | periostin, osteoblast specific factor | -0.0366176 |
| MAP1B | microtubule-associated protein 1B | -0.0351807 |
| CANX | calnexin | -0.0347226 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0337182 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0331186 |
| PALLD | palladin, cytoskeletal associated protein | -0.0330135 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0325812 |
| GLIS3 | GLIS family zinc finger 3 | -0.032483 |
| RIGI | RNA sensor RIG-I | -0.0323417 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0322849 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0321902 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0319568 |
| ATP13A3 | ATPase type 13A3 | -0.0316516 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0303177 |
| CLIC4 | chloride intracellular channel 4 | -0.0297419 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0289379 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0286385 |
| VCAN | versican | -0.0283127 |
| RPL35A | ribosomal protein L35a | -0.0278126 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0274168 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0268761 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0266096 |
| RRBP1 | ribosome binding protein 1 | -0.0263784 |
| CALU | calumenin | -0.026038 |
| ENO1 | enolase 1, (alpha) | -0.0258786 |
| SP100 | SP100 nuclear antigen | -0.0256017 |
| SPAG9 | sperm associated antigen 9 | -0.0255693 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0246277 |
| ACTN4 | actinin, alpha 4 | -0.0246195 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0244477 |
| FBN1 | fibrillin 1 | -0.0236445 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0235376 |
| IER3 | immediate early response 3 | -0.0229263 |
| ANXA2 | annexin A2 | -0.0229145 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0228454 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0228442 |
| GPC6 | glypican 6 | -0.0223809 |
| NAV1 | neuron navigator 1 | -0.0223313 |
| PLSCR1 | phospholipid scramblase 1 | -0.021983 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0217345 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0215314 |
| JAK2 | Janus kinase 2 | -0.0213978 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0213783 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0209809 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0203509 |
| CALD1 | caldesmon 1 | -0.0201017 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0200542 |
| TPM1 | tropomyosin 1 (alpha) | -0.0199111 |
| MT1X | metallothionein 1X | -0.0198763 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0198281 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0197045 |
| FAT1 | FAT atypical cadherin 1 | -0.0196056 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0195267 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0194675 |
| NRP1 | neuropilin 1 | -0.0192791 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0192219 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0192118 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0187936 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0185569 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0182627 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0179149 |
| TMSB4X | thymosin beta 4, X-linked | -0.0177761 |
| ZNF644 | zinc finger protein 644 | -0.0175432 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0173016 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0172056 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0170597 |
| NREP | neuronal regeneration related protein | -0.0170297 |
| HAS2 | hyaluronan synthase 2 | -0.016786 |
