| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.121866 |
| RPS6 | ribosomal protein S6 | 0.0895968 |
| TXNRD1 | thioredoxin reductase 1 | 0.0774388 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.070455 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0660308 |
| FTL | ferritin, light polypeptide | 0.0615683 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0596719 |
| RPL18 | ribosomal protein L18 | 0.0575778 |
| RPS2 | ribosomal protein S2 | 0.054866 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0540378 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0532225 |
| RPS3 | ribosomal protein S3 | 0.0507711 |
| GOLGA4 | golgin A4 | 0.0497823 |
| MKI67 | marker of proliferation Ki-67 | 0.0497436 |
| RPS19 | ribosomal protein S19 | 0.0490931 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0477782 |
| RPL4 | ribosomal protein L4 | 0.0473514 |
| CENPF | centromere protein F, 350/400kDa | 0.0418887 |
| RPL21 | ribosomal protein L21 | 0.0400425 |
| RPS12 | ribosomal protein S12 | 0.0398143 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0396096 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0380726 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0372905 |
| YBX3 | Y box binding protein 3 | 0.0349708 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0340092 |
| OGA | O-GlcNAcase | 0.0336153 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0335617 |
| RPL12 | ribosomal protein L12 | 0.0327008 |
| RPL32 | ribosomal protein L32 | 0.0321542 |
| KIF5B | kinesin family member 5B | 0.0315739 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0315721 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0315557 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0311505 |
| HMGB2 | high mobility group box 2 | 0.0309124 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0304552 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0301197 |
| RPLP2 | ribosomal protein, large, P2 | 0.0300636 |
| SERF2 | small EDRK-rich factor 2 | 0.0297302 |
| EZR | ezrin | 0.0292271 |
| RPS16 | ribosomal protein S16 | 0.0289605 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0280116 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.027558 |
| RPL26 | ribosomal protein L26 | 0.0274155 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0272371 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0268502 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.026573 |
| ZNF292 | zinc finger protein 292 | 0.0262431 |
| YBX1 | Y box binding protein 1 | 0.0258074 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0243929 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0243736 |
| TPM3 | tropomyosin 3 | 0.0242905 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0240661 |
| HDLBP | high density lipoprotein binding protein | 0.0235606 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0235351 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0233404 |
| TPX2 | TPX2, microtubule-associated | 0.0231454 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0229003 |
| CREBRF | CREB3 regulatory factor | 0.0227433 |
| TPI1 | triosephosphate isomerase 1 | 0.0227397 |
| PAPOLA | poly(A) polymerase alpha | 0.0223857 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0221463 |
| H1-0 | H1.0 linker histone | 0.0220955 |
| WWC1 | WW and C2 domain containing 1 | 0.0218488 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0218027 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0214366 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0210723 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.020919 |
| NDUFB9 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 0.0208712 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0208051 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0207693 |
| RACK1 | receptor for activated C kinase 1 | 0.0206893 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0205832 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0204928 |
| UBE3A | ubiquitin protein ligase E3A | 0.0203224 |
| KLF6 | Kruppel-like factor 6 | 0.020238 |
| KRT17 | keratin 17, type I | 0.0201679 |
| NCKAP1 | NCK-associated protein 1 | 0.0199409 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0199334 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0199044 |
| GPX4 | glutathione peroxidase 4 | 0.019804 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0194236 |
| ANLN | anillin, actin binding protein | 0.0193847 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.019255 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0192328 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0191096 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0190925 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0190544 |
| YME1L1 | YME1-like 1 ATPase | 0.0189903 |
| SYAP1 | synapse associated protein 1 | 0.0189744 |
| SF1 | splicing factor 1 | 0.0187569 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0187473 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0186942 |
| ZFP91 | ZFP91 zinc finger protein | 0.0186649 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0185836 |
| TOP1 | topoisomerase (DNA) I | 0.0184044 |
| RTN4 | reticulon 4 | 0.0183297 |
| PDZD8 | PDZ domain containing 8 | 0.0183043 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0181783 |
| RPL7 | ribosomal protein L7 | 0.0181458 |
| RPL36 | ribosomal protein L36 | 0.0181134 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH14 | myosin, heavy chain 14, non-muscle | -0.162068 |
| NDRG1 | N-myc downstream regulated 1 | -0.150546 |
| EXT1 | exostosin glycosyltransferase 1 | -0.135655 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.118333 |
| INTS6 | integrator complex subunit 6 | -0.11744 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0977182 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0862341 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0860985 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0760919 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0747931 |
| RPL35A | ribosomal protein L35a | -0.0679025 |
| LAMA4 | laminin, alpha 4 | -0.0668489 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0657033 |
| SLC45A4 | solute carrier family 45, member 4 | -0.063907 |
| SMAD3 | SMAD family member 3 | -0.0614771 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0599317 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0594342 |
| KRT20 | keratin 20, type I | -0.0591338 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0577286 |
| PKM | pyruvate kinase, muscle | -0.0573152 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0564304 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0554451 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.054036 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0535121 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0528879 |
| MCL1 | myeloid cell leukemia 1 | -0.0514507 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0513907 |
| LYZ | lysozyme | -0.0494603 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.048452 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0479698 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0473701 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0468348 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0446119 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0441281 |
| FRY | furry homolog (Drosophila) | -0.0440229 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0432675 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0410254 |
| FOXO3 | forkhead box O3 | -0.0408736 |
| POF1B | premature ovarian failure, 1B | -0.0405966 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0405617 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0405583 |
| TRIB1 | tribbles pseudokinase 1 | -0.040272 |
| VCL | vinculin | -0.0399584 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0396608 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0395354 |
| CTBP2 | C-terminal binding protein 2 | -0.0395351 |
| DIAPH2 | diaphanous-related formin 2 | -0.0394433 |
| PRKCA | protein kinase C, alpha | -0.038338 |
| ACTG1 | actin gamma 1 | -0.0383066 |
| RPL31 | ribosomal protein L31 | -0.0374158 |
| MYO1E | myosin IE | -0.0372049 |
| DGKH | diacylglycerol kinase, eta | -0.0371414 |
| EXOC4 | exocyst complex component 4 | -0.0367124 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0364957 |
| KRT8 | keratin 8, type II | -0.0361275 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0360203 |
| NF1 | neurofibromin 1 | -0.0356723 |
| RNF213 | ring finger protein 213 | -0.0349711 |
| AGR2 | anterior gradient 2 | -0.0348959 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0345192 |
| ATXN1 | ataxin 1 | -0.0345131 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.034312 |
| NUP98 | nucleoporin 98kDa | -0.0342772 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0342039 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0338256 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0335615 |
| ACTN4 | actinin, alpha 4 | -0.0334799 |
| MAGT1 | magnesium transporter 1 | -0.033479 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.032833 |
| LDHA | lactate dehydrogenase A | -0.0326248 |
| EGR1 | early growth response 1 | -0.0321948 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0319922 |
| RPS13 | ribosomal protein S13 | -0.0317272 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0316632 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0315526 |
| PTK2 | protein tyrosine kinase 2 | -0.0305296 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0305287 |
| POTEF | POTE ankyrin domain family, member F | -0.0301803 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0301091 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0296989 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.029413 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0293123 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0292289 |
| RCOR1 | REST corepressor 1 | -0.0285903 |
| MMP7 | matrix metallopeptidase 7 | -0.0280549 |
| VEGFA | vascular endothelial growth factor A | -0.0280372 |
| FBXO11 | F-box protein 11 | -0.0280351 |
| UBAP2 | ubiquitin associated protein 2 | -0.0280101 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0276441 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0274749 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0274324 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0274023 |
| TJP1 | tight junction protein 1 | -0.0272256 |
| ANKRD11 | ankyrin repeat domain 11 | -0.027101 |
| TMEM65 | transmembrane protein 65 | -0.0270634 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0270321 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0270209 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0269667 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0264747 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0263529 |
