| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS2 | ribosomal protein S2 | 0.0864774 |
| CLU | clusterin | 0.0581651 |
| FLNA | filamin A, alpha | 0.0542651 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0530097 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0519713 |
| KRT6A | keratin 6A, type II | 0.0501098 |
| PODXL | podocalyxin-like | 0.0482152 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0474566 |
| RPS6 | ribosomal protein S6 | 0.0467788 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0461099 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0421041 |
| RPS3 | ribosomal protein S3 | 0.0405931 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0369095 |
| RACK1 | receptor for activated C kinase 1 | 0.0362698 |
| RPL4 | ribosomal protein L4 | 0.0350056 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0343864 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0326621 |
| TLN1 | talin 1 | 0.032319 |
| PLAT | plasminogen activator, tissue | 0.0322549 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.03097 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0298647 |
| TMF1 | TATA element modulatory factor 1 | 0.0291898 |
| CENPF | centromere protein F, 350/400kDa | 0.0291182 |
| PTMA | prothymosin, alpha | 0.0281188 |
| RPS12 | ribosomal protein S12 | 0.0280017 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0277547 |
| RPL21 | ribosomal protein L21 | 0.0277376 |
| FLNB | filamin B, beta | 0.0270339 |
| ITGB4 | integrin, beta 4 | 0.0267244 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0261088 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0258859 |
| CD99 | CD99 molecule | 0.0257979 |
| MXRA5 | matrix-remodelling associated 5 | 0.0254409 |
| TPM3 | tropomyosin 3 | 0.0254086 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0252454 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0249538 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0247674 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0244922 |
| EGR1 | early growth response 1 | 0.0241962 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0236995 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0232689 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0232059 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0225934 |
| SULF1 | sulfatase 1 | 0.0225273 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0224026 |
| LAMA5 | laminin, alpha 5 | 0.0222926 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0219778 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0216871 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0201845 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0198576 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0195656 |
| NAV2 | neuron navigator 2 | 0.0194218 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0190945 |
| RIN2 | Ras and Rab interactor 2 | 0.0189407 |
| S100A11 | S100 calcium binding protein A11 | 0.0188975 |
| CAMLG | calcium modulating ligand | 0.0186073 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0185256 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0184617 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0183892 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0183516 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0182839 |
| FSCN1 | fascin actin-bundling protein 1 | 0.017932 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0179202 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0177152 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0173819 |
| TMEM41B | transmembrane protein 41B | 0.0173486 |
| LMNA | lamin A/C | 0.0173132 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0170237 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0169277 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0168421 |
| HDGF | hepatoma-derived growth factor | 0.016653 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0166237 |
| RPL14 | ribosomal protein L14 | 0.0164181 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0163837 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0160263 |
| RTN4 | reticulon 4 | 0.0160158 |
| HMGB2 | high mobility group box 2 | 0.0155804 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.015508 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.0154398 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0152966 |
| RBM15 | RNA binding motif protein 15 | 0.0152328 |
| MYO10 | myosin X | 0.0151387 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0150944 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.015084 |
| TNS4 | tensin 4 | 0.015021 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0150094 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0149584 |
| RIPOR1 | RHO family interacting cell polarization regulator 1 | 0.0149512 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0148749 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0148212 |
| CNN3 | calponin 3, acidic | 0.0147324 |
| ATXN2L | ataxin 2-like | 0.0143115 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0142706 |
| PMM2 | phosphomannomutase 2 | 0.014262 |
| BSDC1 | BSD domain containing 1 | 0.0142554 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.0142195 |
| DHFR | dihydrofolate reductase | 0.0141461 |
| VCL | vinculin | 0.0141175 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0139451 |
| VIM | vimentin | 0.013738 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.196293 |
| LDHA | lactate dehydrogenase A | -0.0938147 |
| POTEF | POTE ankyrin domain family, member F | -0.0881428 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.083433 |
| MT2A | metallothionein 2A | -0.0798004 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0793168 |
| MYOF | myoferlin | -0.0769395 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.075186 |
| INTS6 | integrator complex subunit 6 | -0.0640327 |
| S100A10 | S100 calcium binding protein A10 | -0.0588446 |
| IGF2 | insulin-like growth factor 2 | -0.0573472 |
| DPYD | dihydropyrimidine dehydrogenase | -0.056452 |
| AHNAK | AHNAK nucleoprotein | -0.053679 |
| PGK1 | phosphoglycerate kinase 1 | -0.0529064 |
| RPLP1 | ribosomal protein, large, P1 | -0.0523219 |
| ENO1 | enolase 1, (alpha) | -0.0477552 |
| RPL35A | ribosomal protein L35a | -0.0472733 |
| RPS24 | ribosomal protein S24 | -0.0470261 |
| RPL23 | ribosomal protein L23 | -0.0463472 |
| RPS13 | ribosomal protein S13 | -0.0461055 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0460203 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0449545 |
| CD44 | CD44 molecule (Indian blood group) | -0.0440163 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0436502 |
| FOXP1 | forkhead box P1 | -0.0434665 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0419678 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0418063 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0413922 |
| PTK2 | protein tyrosine kinase 2 | -0.0405326 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0403767 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0403321 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0401267 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0399518 |
| FTL | ferritin, light polypeptide | -0.0387116 |
| RPL11 | ribosomal protein L11 | -0.0377606 |
| LMO7 | LIM domain 7 | -0.0370264 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.036899 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0357356 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0354437 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0350538 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0349076 |
| B2M | beta-2-microglobulin | -0.0347112 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0343236 |
| ACTN4 | actinin, alpha 4 | -0.0341154 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0340504 |
| ITGA6 | integrin, alpha 6 | -0.0335252 |
| HLA-B | major histocompatibility complex, class I, B | -0.0332903 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0329486 |
| SULF2 | sulfatase 2 | -0.032879 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0322658 |
| MT1E | metallothionein 1E | -0.0322302 |
| FOXO1 | forkhead box O1 | -0.0318232 |
| ANXA2 | annexin A2 | -0.0313753 |
| FNDC3B | fibronectin type III domain containing 3B | -0.031215 |
| CDK6 | cyclin-dependent kinase 6 | -0.0307912 |
| UBC | ubiquitin C | -0.0307444 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0306691 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0303044 |
| TMSB4X | thymosin beta 4, X-linked | -0.0301424 |
| EMP1 | epithelial membrane protein 1 | -0.0301355 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0300689 |
| SMYD3 | SET and MYND domain containing 3 | -0.0300658 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0299612 |
| JMJD1C | jumonji domain containing 1C | -0.0298954 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0298704 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0298533 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0298326 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0298109 |
| MEF2A | myocyte enhancer factor 2A | -0.0296964 |
| RAI14 | retinoic acid induced 14 | -0.0296465 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0294034 |
| PLTP | phospholipid transfer protein | -0.0292206 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0287617 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0283591 |
| MECOM | MDS1 and EVI1 complex locus | -0.0283308 |
| S100A6 | S100 calcium binding protein A6 | -0.0282262 |
| DENND4C | DENN/MADD domain containing 4C | -0.0281352 |
| SDCBP | syndecan binding protein (syntenin) | -0.0279222 |
| FBXO11 | F-box protein 11 | -0.0278441 |
| RPL19 | ribosomal protein L19 | -0.0277303 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0274766 |
| BSG | basigin (Ok blood group) | -0.0274068 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0274043 |
| RLF | rearranged L-myc fusion | -0.0272036 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0271865 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0271599 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0269527 |
| COPA | coatomer protein complex, subunit alpha | -0.0267722 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0267035 |
| GNAS | GNAS complex locus | -0.0265587 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0262812 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0262317 |
| OSMR | oncostatin M receptor | -0.0261252 |
| RPS21 | ribosomal protein S21 | -0.0258853 |
| TPM4 | tropomyosin 4 | -0.0258521 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0258016 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0257638 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0256554 |
| SPAG9 | sperm associated antigen 9 | -0.025637 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0249628 |
