| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0463864 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0396138 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0381242 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0348115 |
| MKI67 | marker of proliferation Ki-67 | 0.0326018 |
| RPS6 | ribosomal protein S6 | 0.0315319 |
| ASPH | aspartate beta-hydroxylase | 0.0314913 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0307698 |
| FLNA | filamin A, alpha | 0.0306427 |
| CCNL1 | cyclin L1 | 0.0273773 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0256546 |
| CENPF | centromere protein F, 350/400kDa | 0.0255436 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0246316 |
| AXL | AXL receptor tyrosine kinase | 0.0237178 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0234212 |
| IL6ST | interleukin 6 signal transducer | 0.0233763 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0224097 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0223421 |
| TLN1 | talin 1 | 0.021343 |
| DIAPH3 | diaphanous-related formin 3 | 0.0212923 |
| RPS2 | ribosomal protein S2 | 0.0210221 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0209023 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0208224 |
| PNN | pinin, desmosome associated protein | 0.0206544 |
| TPM3 | tropomyosin 3 | 0.0203471 |
| TPX2 | TPX2, microtubule-associated | 0.0202218 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0199814 |
| PRELID2 | PRELI domain containing 2 | 0.0196762 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0193729 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0193719 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0193651 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0192495 |
| DST | dystonin | 0.0190803 |
| MSN | moesin | 0.0190467 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.018827 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0183399 |
| NAV2 | neuron navigator 2 | 0.0182357 |
| FRMD4A | FERM domain containing 4A | 0.0181479 |
| CKAP5 | cytoskeleton associated protein 5 | 0.018121 |
| STC2 | stanniocalcin 2 | 0.0180566 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.017723 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0175859 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0174682 |
| FNDC3B | fibronectin type III domain containing 3B | 0.017355 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0173027 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0171986 |
| RUNX1 | runt-related transcription factor 1 | 0.017188 |
| CD44 | CD44 molecule (Indian blood group) | 0.0169353 |
| GOLGB1 | golgin B1 | 0.016564 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0164573 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0164182 |
| TUBA1B | tubulin, alpha 1b | 0.0163649 |
| CENPP | centromere protein P | 0.0163637 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0161452 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0158843 |
| FNIP1 | folliculin interacting protein 1 | 0.0154137 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0153992 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0151735 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.015131 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.01512 |
| TUBA1C | tubulin, alpha 1c | 0.0150461 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0149889 |
| COL5A1 | collagen, type V, alpha 1 | 0.0148582 |
| VMP1 | vacuole membrane protein 1 | 0.0148424 |
| RPL4 | ribosomal protein L4 | 0.0148312 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0147834 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0146786 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0146417 |
| CDK19 | cyclin-dependent kinase 19 | 0.0145711 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0144627 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0144545 |
| PCBP2 | poly(rC) binding protein 2 | 0.014434 |
| RAD51B | RAD51 paralog B | 0.014352 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0142983 |
| SMAD3 | SMAD family member 3 | 0.0142655 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0141386 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0139042 |
| VCL | vinculin | 0.0138164 |
| RPL21 | ribosomal protein L21 | 0.0136924 |
| RPS12 | ribosomal protein S12 | 0.013686 |
| EXOC4 | exocyst complex component 4 | 0.0136548 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0136116 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0135466 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0134094 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0130517 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0130387 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0130076 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0130007 |
| H1-4 | H1.4 linker histone, cluster member | 0.0129997 |
| EGFR | epidermal growth factor receptor | 0.0128976 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0128698 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0128564 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0126091 |
| PODXL | podocalyxin-like | 0.0125641 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0124359 |
| CCDC14 | coiled-coil domain containing 14 | 0.0124241 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0122919 |
| HDAC9 | histone deacetylase 9 | 0.0122638 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0122388 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0122062 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.145656 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.12881 |
| FTL | ferritin, light polypeptide | -0.115577 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0866961 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0851097 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0817123 |
| DEK | DEK proto-oncogene | -0.0785926 |
| NDRG1 | N-myc downstream regulated 1 | -0.0748612 |
| LDHA | lactate dehydrogenase A | -0.0649069 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0625775 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0574582 |
| MT1X | metallothionein 1X | -0.0572629 |
| PGK1 | phosphoglycerate kinase 1 | -0.0559389 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0550124 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0536163 |
| HLA-B | major histocompatibility complex, class I, B | -0.0532135 |
| ADM | adrenomedullin | -0.0498073 |
| ANXA2 | annexin A2 | -0.0454077 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0436286 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0418381 |
| TXNRD1 | thioredoxin reductase 1 | -0.0394995 |
| RPL35A | ribosomal protein L35a | -0.038798 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0356705 |
| ENO1 | enolase 1, (alpha) | -0.0352609 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0352156 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0327239 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0322917 |
| SPAG9 | sperm associated antigen 9 | -0.0317528 |
| CANX | calnexin | -0.0316347 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0289584 |
| STK4 | serine/threonine kinase 4 | -0.0289135 |
| KPNB1 | karyopherin (importin) beta 1 | -0.02881 |
| RLF | rearranged L-myc fusion | -0.0286032 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0283405 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0282163 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0281682 |
| TPD52 | tumor protein D52 | -0.0280537 |
| S100A10 | S100 calcium binding protein A10 | -0.0274455 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0271196 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0270904 |
| POTEF | POTE ankyrin domain family, member F | -0.0265319 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.026515 |
| UBC | ubiquitin C | -0.0262318 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0254529 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0252915 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0252909 |
| HLA-C | major histocompatibility complex, class I, C | -0.0252508 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0248303 |
| JUN | jun proto-oncogene | -0.02457 |
| ANXA1 | annexin A1 | -0.0243016 |
| TPM4 | tropomyosin 4 | -0.0238811 |
| ACTG1 | actin gamma 1 | -0.0238297 |
| TMSB10 | thymosin beta 10 | -0.0238276 |
| PTMA | prothymosin, alpha | -0.0238014 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0237204 |
| USP3 | ubiquitin specific peptidase 3 | -0.0236101 |
| CUL4B | cullin 4B | -0.0236056 |
| B2M | beta-2-microglobulin | -0.0233863 |
| CAVIN1 | caveolae associated protein 1 | -0.0233682 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0231453 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0227869 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0222098 |
| GNAS | GNAS complex locus | -0.0219383 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0218366 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.021706 |
| MAP4 | microtubule-associated protein 4 | -0.0216048 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0214468 |
| TMSB4X | thymosin beta 4, X-linked | -0.020758 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0207263 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0206942 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0205087 |
| UFM1 | ubiquitin-fold modifier 1 | -0.020274 |
| IER3 | immediate early response 3 | -0.0201212 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0198233 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0197333 |
| PLIN2 | perilipin 2 | -0.0195993 |
| WDR45B | WD repeat domain 45B | -0.0195977 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0195916 |
| TKT | transketolase | -0.0195612 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0195592 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0194037 |
| SEPTIN7 | septin 7 | -0.01914 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0189542 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0189408 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0188467 |
| AHNAK | AHNAK nucleoprotein | -0.0188185 |
| DENND4C | DENN/MADD domain containing 4C | -0.0187757 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0185676 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0181116 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0179925 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.017795 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0177366 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.017579 |
| LOX | lysyl oxidase | -0.017523 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0175056 |
| RTN3 | reticulon 3 | -0.0174053 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0172396 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.017237 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0171459 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0169192 |
