| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.113468 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0884544 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0829078 |
| RPS2 | ribosomal protein S2 | 0.0731554 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0672027 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0600715 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0600409 |
| RPS12 | ribosomal protein S12 | 0.0531854 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0512883 |
| MKI67 | marker of proliferation Ki-67 | 0.0452327 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0438418 |
| RPS3 | ribosomal protein S3 | 0.0429668 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0401004 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0353073 |
| RPL4 | ribosomal protein L4 | 0.0344183 |
| TPI1 | triosephosphate isomerase 1 | 0.034206 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.034124 |
| ANLN | anillin, actin binding protein | 0.0321569 |
| RPS17 | ribosomal protein S17 | 0.0315707 |
| TPM3 | tropomyosin 3 | 0.0315161 |
| RPL37A | ribosomal protein L37a | 0.0312338 |
| TUBA1B | tubulin, alpha 1b | 0.0304064 |
| S100A11 | S100 calcium binding protein A11 | 0.0301238 |
| RPS8 | ribosomal protein S8 | 0.0297 |
| RPL21 | ribosomal protein L21 | 0.0296407 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0279529 |
| VIM | vimentin | 0.0274946 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0273535 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0267885 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0266009 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.02633 |
| RPL18 | ribosomal protein L18 | 0.0262617 |
| PCBP2 | poly(rC) binding protein 2 | 0.0257738 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0251616 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0245275 |
| RPL28 | ribosomal protein L28 | 0.0244059 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0243123 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0237139 |
| TNS4 | tensin 4 | 0.0235612 |
| MUC1 | mucin 1, cell surface associated | 0.0224549 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0222016 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0219116 |
| CCNL1 | cyclin L1 | 0.0217961 |
| FLNA | filamin A, alpha | 0.0215111 |
| HMGB2 | high mobility group box 2 | 0.0213438 |
| RPL11 | ribosomal protein L11 | 0.0209197 |
| PAPOLA | poly(A) polymerase alpha | 0.0202924 |
| BRD4 | bromodomain containing 4 | 0.0202476 |
| FANCI | Fanconi anemia, complementation group I | 0.0197626 |
| SET | SET nuclear proto-oncogene | 0.0197211 |
| ITGB4 | integrin, beta 4 | 0.0195871 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0195559 |
| CENPF | centromere protein F, 350/400kDa | 0.0187521 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.01869 |
| YBX1 | Y box binding protein 1 | 0.0185916 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.018051 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0175668 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0175552 |
| FAM13A | family with sequence similarity 13, member A | 0.0173371 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0173092 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0172138 |
| RIOK3 | RIO kinase 3 | 0.0169979 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0164159 |
| RPS7 | ribosomal protein S7 | 0.0163819 |
| PNN | pinin, desmosome associated protein | 0.0163705 |
| ATF4 | activating transcription factor 4 | 0.0163416 |
| RPL10A | ribosomal protein L10a | 0.0159943 |
| TPX2 | TPX2, microtubule-associated | 0.015899 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0157937 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0157334 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0154119 |
| TMF1 | TATA element modulatory factor 1 | 0.0153841 |
| SMAD3 | SMAD family member 3 | 0.0153383 |
| EFCAB14 | EF-hand calcium binding domain 14 | 0.0153177 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0151105 |
| RPL35 | ribosomal protein L35 | 0.0151097 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0150795 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0150402 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0148907 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0148335 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0147189 |
| RPL12 | ribosomal protein L12 | 0.0145493 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0145303 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0144293 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.0141617 |
| RPS27 | ribosomal protein S27 | 0.0140957 |
| MEA1 | male-enhanced antigen 1 | 0.0139878 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0139868 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0138751 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0138372 |
| EGR1 | early growth response 1 | 0.0138207 |
| HDGF | hepatoma-derived growth factor | 0.0138062 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.013711 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0133215 |
| WBP11 | WW domain binding protein 11 | 0.013007 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.012995 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0129245 |
| RPLP2 | ribosomal protein, large, P2 | 0.0129025 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0127717 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0127151 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.189532 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.186713 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.145652 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.114245 |
| LMO7 | LIM domain 7 | -0.103278 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0958816 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.094341 |
| NPSR1 | neuropeptide S receptor 1 | -0.090413 |
| EMP1 | epithelial membrane protein 1 | -0.0871217 |
| ANXA2 | annexin A2 | -0.0865031 |
| PGK1 | phosphoglycerate kinase 1 | -0.0830656 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0813634 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0802695 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0710631 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0692059 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0687758 |
| TMEM123 | transmembrane protein 123 | -0.0665523 |
| CD2AP | CD2-associated protein | -0.0635122 |
| AGR2 | anterior gradient 2 | -0.0633925 |
| RPL35A | ribosomal protein L35a | -0.0628339 |
| TMC5 | transmembrane channel-like 5 | -0.0599052 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0559113 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0558523 |
| AHR | aryl hydrocarbon receptor | -0.0543946 |
| FAT1 | FAT atypical cadherin 1 | -0.0541263 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0538768 |
| TNIK | TRAF2 and NCK interacting kinase | -0.053532 |
| CANX | calnexin | -0.0534497 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0505294 |
| CDK6 | cyclin-dependent kinase 6 | -0.0502683 |
| HLA-E | major histocompatibility complex, class I, E | -0.0502544 |
| ATF5 | activating transcription factor 5 | -0.0486656 |
| EHBP1 | EH domain binding protein 1 | -0.0476522 |
| TMSB10 | thymosin beta 10 | -0.0475085 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0471109 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0470544 |
| EPCAM | epithelial cell adhesion molecule | -0.0470395 |
| RPLP1 | ribosomal protein, large, P1 | -0.0443775 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0442282 |
| ITGA6 | integrin, alpha 6 | -0.0437804 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0436789 |
| PHF14 | PHD finger protein 14 | -0.0435508 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0434613 |
| S100A6 | S100 calcium binding protein A6 | -0.0434099 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0427954 |
| WDR45B | WD repeat domain 45B | -0.0416225 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0415463 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0412556 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0411845 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0411303 |
| RNF213 | ring finger protein 213 | -0.0408265 |
| MECOM | MDS1 and EVI1 complex locus | -0.0405395 |
| POF1B | premature ovarian failure, 1B | -0.0404826 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0404642 |
| NF1 | neurofibromin 1 | -0.0404021 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0402871 |
| FOXP1 | forkhead box P1 | -0.0400276 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0388516 |
| HLA-C | major histocompatibility complex, class I, C | -0.038549 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0384732 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0381401 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0380714 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0380235 |
| AHNAK | AHNAK nucleoprotein | -0.0378561 |
| RPS24 | ribosomal protein S24 | -0.0372691 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.037164 |
| ACTN4 | actinin, alpha 4 | -0.0370185 |
| DIAPH2 | diaphanous-related formin 2 | -0.0367443 |
| RUNX1 | runt-related transcription factor 1 | -0.0360669 |
| SIK3 | SIK family kinase 3 | -0.0360313 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0360153 |
| COBL | cordon-bleu WH2 repeat protein | -0.0358966 |
| RRBP1 | ribosome binding protein 1 | -0.0358085 |
| AOPEP | aminopeptidase O (putative) | -0.0354523 |
| KRT8 | keratin 8, type II | -0.035382 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0349957 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0348506 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0344756 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.034377 |
| S100A10 | S100 calcium binding protein A10 | -0.0342669 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.034078 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0339257 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0337014 |
| POTEF | POTE ankyrin domain family, member F | -0.0336148 |
| MSI2 | musashi RNA-binding protein 2 | -0.033453 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0327189 |
| TCF12 | transcription factor 12 | -0.0326202 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0323989 |
| FBXO11 | F-box protein 11 | -0.0322875 |
| KRT18 | keratin 18, type I | -0.0320195 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0319254 |
| MORF4L2 | mortality factor 4 like 2 | -0.0318599 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0316416 |
| RPL23 | ribosomal protein L23 | -0.0315063 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0315034 |
| ABLIM1 | actin binding LIM protein 1 | -0.0313248 |
| CUX1 | cut-like homeobox 1 | -0.0312093 |
| MCU | mitochondrial calcium uniporter | -0.0311799 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0311248 |
| PRKCA | protein kinase C, alpha | -0.0310329 |
