| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.142366 |
| RPS6 | ribosomal protein S6 | 0.0631018 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0538142 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0536156 |
| FLNA | filamin A, alpha | 0.0535836 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.048454 |
| RPS2 | ribosomal protein S2 | 0.0438236 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0392905 |
| RPL4 | ribosomal protein L4 | 0.0335048 |
| YBX3 | Y box binding protein 3 | 0.0323298 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0304133 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0288485 |
| RPS12 | ribosomal protein S12 | 0.027915 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0264046 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0245251 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0240152 |
| TPI1 | triosephosphate isomerase 1 | 0.0237746 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0230226 |
| PTCHD4 | patched domain containing 4 | 0.0227871 |
| TLE4 | transducin-like enhancer of split 4 | 0.0226017 |
| EPHA4 | EPH receptor A4 | 0.0222173 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0220096 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.021274 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0210277 |
| WDR43 | WD repeat domain 43 | 0.0208352 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0206713 |
| CCNL1 | cyclin L1 | 0.0202571 |
| RPS19 | ribosomal protein S19 | 0.0202296 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0201143 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0200559 |
| RPL21 | ribosomal protein L21 | 0.019962 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0198559 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0197657 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0196308 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0192875 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0188031 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.0180304 |
| POLH | polymerase (DNA directed), eta | 0.017792 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0175228 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0173469 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.017074 |
| TPM3 | tropomyosin 3 | 0.0167247 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0166436 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0162617 |
| PLK2 | polo-like kinase 2 | 0.0157484 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0157143 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0151704 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0147187 |
| RACK1 | receptor for activated C kinase 1 | 0.0145737 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0144553 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.014228 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0141639 |
| RPL37A | ribosomal protein L37a | 0.0141331 |
| RPS17 | ribosomal protein S17 | 0.0138041 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0137057 |
| SESN1 | sestrin 1 | 0.0135708 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 0.0134874 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0134698 |
| FBXO22 | F-box protein 22 | 0.0134216 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0134052 |
| NUP58 | nucleoporin 58 | 0.0133347 |
| TLN1 | talin 1 | 0.0130742 |
| ATF3 | activating transcription factor 3 | 0.0130691 |
| MLEC | malectin | 0.0130291 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0129085 |
| VGF | VGF nerve growth factor inducible | 0.0125685 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0122524 |
| RO60 | Ro60, Y RNA binding protein | 0.0120791 |
| PNN | pinin, desmosome associated protein | 0.0119847 |
| AXL | AXL receptor tyrosine kinase | 0.0119837 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0119114 |
| PCBP2 | poly(rC) binding protein 2 | 0.0118978 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0118734 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0117984 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0117855 |
| NOPCHAP1 | NOP protein chaperone 1 | 0.0115652 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0115089 |
| YBX1 | Y box binding protein 1 | 0.0114207 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0113355 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0113101 |
| ASTN2 | astrotactin 2 | 0.0112694 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0110613 |
| MYO6 | myosin VI | 0.0109453 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0107066 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | 0.0106252 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.0105951 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0105797 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0105639 |
| BRD2 | bromodomain containing 2 | 0.010492 |
| E2F7 | E2F transcription factor 7 | 0.0104616 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0103369 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0102479 |
| SET | SET nuclear proto-oncogene | 0.0102469 |
| RPL13A | ribosomal protein L13a | 0.0102345 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0101577 |
| SMTN | smoothelin | 0.0100287 |
| SNX2 | sorting nexin 2 | 0.00997051 |
| HDAC3 | histone deacetylase 3 | 0.00995245 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.00985557 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.00983879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | -0.195828 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.174618 |
| GPC6 | glypican 6 | -0.162114 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.123367 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.121064 |
| EXT1 | exostosin glycosyltransferase 1 | -0.119774 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.118365 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.116018 |
| MMP12 | matrix metallopeptidase 12 | -0.115255 |
| VIM | vimentin | -0.114436 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.10374 |
| ASPH | aspartate beta-hydroxylase | -0.102636 |
| LSAMP | limbic system-associated membrane protein | -0.101251 |
| PTK2 | protein tyrosine kinase 2 | -0.0977694 |
| DTNA | dystrobrevin, alpha | -0.0975766 |
| RUNX1 | runt-related transcription factor 1 | -0.0897417 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0845086 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0830753 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0813077 |
| NAV1 | neuron navigator 1 | -0.079382 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0790978 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0788006 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0784803 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0764309 |
| KIAA1549L | KIAA1549-like | -0.0750466 |
| ACTG1 | actin gamma 1 | -0.074808 |
| DST | dystonin | -0.0741392 |
| USP34 | ubiquitin specific peptidase 34 | -0.07048 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0664975 |
| NTM | neurotrimin | -0.0663086 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0662672 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0636691 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0635077 |
| AHNAK | AHNAK nucleoprotein | -0.0633378 |
| LDHA | lactate dehydrogenase A | -0.061585 |
| CALD1 | caldesmon 1 | -0.0611658 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0576111 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0561037 |
| SBF2 | SET binding factor 2 | -0.0559112 |
| FOXP1 | forkhead box P1 | -0.0541517 |
| PARD3 | par-3 family cell polarity regulator | -0.0538403 |
| MYO10 | myosin X | -0.0530927 |
| PTMA | prothymosin, alpha | -0.0530709 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0530033 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0523469 |
| CDK6 | cyclin-dependent kinase 6 | -0.0521143 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0519332 |
| CDH13 | cadherin 13 | -0.0511067 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0499674 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0498949 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0497742 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.049273 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0483686 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0482871 |
| ERBIN | erbb2 interacting protein | -0.0482575 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0480446 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0472527 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0471367 |
| TMSB10 | thymosin beta 10 | -0.0466495 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0462114 |
| RPL23 | ribosomal protein L23 | -0.0451047 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0448579 |
| SMYD3 | SET and MYND domain containing 3 | -0.0443699 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0439371 |
| PGK1 | phosphoglycerate kinase 1 | -0.0431688 |
| PRKCE | protein kinase C, epsilon | -0.042891 |
| FMNL2 | formin-like 2 | -0.0421356 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0415331 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0414975 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0413452 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0408569 |
| CDK14 | cyclin-dependent kinase 14 | -0.0406938 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0403981 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0403446 |
| VCL | vinculin | -0.0403396 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0402174 |
| SSH2 | slingshot protein phosphatase 2 | -0.0399054 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0393367 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0384828 |
| ANO6 | anoctamin 6 | -0.0383083 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0381377 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0381243 |
| DIAPH2 | diaphanous-related formin 2 | -0.0380856 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0380495 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.037912 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0376939 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0376672 |
| NF1 | neurofibromin 1 | -0.0374314 |
| MSR1 | macrophage scavenger receptor 1 | -0.0371424 |
| JMJD1C | jumonji domain containing 1C | -0.03667 |
| ZNF804A | zinc finger protein 804A | -0.0365918 |
| TMPRSS15 | transmembrane protease, serine 15 | -0.0362042 |
| POTEF | POTE ankyrin domain family, member F | -0.0356603 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0348775 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0345311 |
| MAP4 | microtubule-associated protein 4 | -0.0341525 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.034061 |
| ATXN1 | ataxin 1 | -0.0339523 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0338645 |
| RAD51B | RAD51 paralog B | -0.0338213 |
