| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Epirubicin (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.101627 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0654648 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0535768 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0489893 |
| TXNIP | thioredoxin interacting protein | 0.047905 |
| RPS2 | ribosomal protein S2 | 0.0403203 |
| FAM13A | family with sequence similarity 13, member A | 0.0402107 |
| NDRG1 | N-myc downstream regulated 1 | 0.0398463 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0374162 |
| EREG | epiregulin | 0.0306846 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0272329 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0270642 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0266289 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0262303 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0257449 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0256729 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.024837 |
| VEGFA | vascular endothelial growth factor A | 0.0245838 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0240337 |
| WAC | WW domain containing adaptor with coiled-coil | 0.022675 |
| RPL4 | ribosomal protein L4 | 0.0225813 |
| RNF145 | ring finger protein 145 | 0.0223804 |
| KITLG | KIT ligand | 0.02223 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0217657 |
| CCNY | cyclin Y | 0.0213498 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0207641 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0207003 |
| MUC13 | mucin 13, cell surface associated | 0.0195289 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0194925 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0194197 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0190063 |
| CCNL1 | cyclin L1 | 0.0184921 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0180163 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0179828 |
| RPS12 | ribosomal protein S12 | 0.0173406 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0172663 |
| GDF15 | growth differentiation factor 15 | 0.0170067 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0164372 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0163644 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.016252 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.016218 |
| ZNF292 | zinc finger protein 292 | 0.0160682 |
| RPL21 | ribosomal protein L21 | 0.0158185 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0157932 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0157795 |
| EHF | ets homologous factor | 0.0149807 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0147726 |
| TFG | TRK-fused gene | 0.0144194 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.0143759 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0142942 |
| DSPP | dentin sialophosphoprotein | 0.0140121 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0139555 |
| MXD1 | MAX dimerization protein 1 | 0.0139244 |
| SUCO | SUN domain containing ossification factor | 0.0138678 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0138167 |
| NCKAP1 | NCK-associated protein 1 | 0.0137833 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0136619 |
| RPL3 | ribosomal protein L3 | 0.0136133 |
| TMF1 | TATA element modulatory factor 1 | 0.0135345 |
| RPS6 | ribosomal protein S6 | 0.0133944 |
| RNF19B | ring finger protein 19B | 0.013171 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0131043 |
| NBAS | neuroblastoma amplified sequence | 0.0130842 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0130686 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0130535 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0129203 |
| CASZ1 | castor zinc finger 1 | 0.0129052 |
| ATF3 | activating transcription factor 3 | 0.0128908 |
| PCBP2 | poly(rC) binding protein 2 | 0.0128606 |
| HELZ | helicase with zinc finger | 0.0126095 |
| DNM2 | dynamin 2 | 0.0126093 |
| SESN1 | sestrin 1 | 0.0125238 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0124876 |
| USP3 | ubiquitin specific peptidase 3 | 0.0122696 |
| MED13L | mediator complex subunit 13-like | 0.012164 |
| BRD4 | bromodomain containing 4 | 0.012063 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0120171 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0117919 |
| TNS4 | tensin 4 | 0.0115234 |
| SESN2 | sestrin 2 | 0.0112442 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0111405 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0111339 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0111041 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0110059 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0108864 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0108691 |
| FBXO32 | F-box protein 32 | 0.0108112 |
| PLXNB2 | plexin B2 | 0.0107873 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0107359 |
| FBXO42 | F-box protein 42 | 0.0105374 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0105283 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0104719 |
| NUP58 | nucleoporin 58 | 0.0104509 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0103653 |
| RIOK3 | RIO kinase 3 | 0.0103453 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0103176 |
| RBM39 | RNA binding motif protein 39 | 0.0102515 |
| SNX2 | sorting nexin 2 | 0.0101634 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.010063 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0100481 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.154954 |
| PTMA | prothymosin, alpha | -0.123619 |
| NPSR1 | neuropeptide S receptor 1 | -0.10026 |
| TMSB10 | thymosin beta 10 | -0.0976956 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0947347 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0895968 |
| MYO1E | myosin IE | -0.0815455 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.080344 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0779558 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0751585 |
| GPHN | gephyrin | -0.0684483 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0674174 |
| ITGA6 | integrin, alpha 6 | -0.0647186 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0618106 |
| ASPH | aspartate beta-hydroxylase | -0.0596937 |
| LDHA | lactate dehydrogenase A | -0.0594932 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0573189 |
| VCL | vinculin | -0.057181 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0567242 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0564774 |
| EPCAM | epithelial cell adhesion molecule | -0.0551674 |
| ANXA2 | annexin A2 | -0.0528082 |
| AHNAK | AHNAK nucleoprotein | -0.0518145 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0517479 |
| ACTG1 | actin gamma 1 | -0.0514867 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0513703 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0511301 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0507592 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0484479 |
| EXT1 | exostosin glycosyltransferase 1 | -0.044853 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0447145 |
| CANX | calnexin | -0.0438678 |
| RPL35A | ribosomal protein L35a | -0.0418765 |
| PGK1 | phosphoglycerate kinase 1 | -0.0417912 |
| ONECUT3 | one cut homeobox 3 | -0.0414898 |
| RPLP1 | ribosomal protein, large, P1 | -0.0413494 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0410499 |
| LMO7 | LIM domain 7 | -0.040796 |
| TPM4 | tropomyosin 4 | -0.0404235 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0403093 |
| RAB10 | RAB10, member RAS oncogene family | -0.0382372 |
| CD44 | CD44 molecule (Indian blood group) | -0.0379765 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0378731 |
| NEBL | nebulette | -0.0372697 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0369862 |
| PDLIM5 | PDZ and LIM domain 5 | -0.036828 |
| RPLP0 | ribosomal protein, large, P0 | -0.0360838 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0340454 |
| RPS24 | ribosomal protein S24 | -0.0340291 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0337212 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0335451 |
| SMYD3 | SET and MYND domain containing 3 | -0.0335428 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0332028 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0330977 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0324538 |
| PKP2 | plakophilin 2 | -0.0324323 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0313801 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0312216 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0310544 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0304682 |
| TRIM2 | tripartite motif containing 2 | -0.0301161 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0299513 |
| RPL23 | ribosomal protein L23 | -0.0284766 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.028309 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0282307 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0282038 |
| FOXP1 | forkhead box P1 | -0.0281489 |
| ACTN4 | actinin, alpha 4 | -0.0280427 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.027984 |
| LAMA4 | laminin, alpha 4 | -0.0270212 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0268785 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0268252 |
| PRSS3 | protease, serine, 3 | -0.0268033 |
| ABR | active BCR-related | -0.026714 |
| KRT18 | keratin 18, type I | -0.0259949 |
| CLOCK | clock circadian regulator | -0.0259643 |
| PKM | pyruvate kinase, muscle | -0.025959 |
| MT2A | metallothionein 2A | -0.0259467 |
| POTEF | POTE ankyrin domain family, member F | -0.0259342 |
| CCND1 | cyclin D1 | -0.0258302 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0258288 |
| MYO1D | myosin ID | -0.025532 |
| ABLIM1 | actin binding LIM protein 1 | -0.0254416 |
| SH3D19 | SH3 domain containing 19 | -0.0254229 |
| CADPS | Ca++-dependent secretion activator | -0.0251711 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0251056 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0249849 |
| IER3 | immediate early response 3 | -0.0248865 |
| S100A6 | S100 calcium binding protein A6 | -0.0247822 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0247582 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0247575 |
| DEK | DEK proto-oncogene | -0.024522 |
| POF1B | premature ovarian failure, 1B | -0.0243105 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0243061 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0242744 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0241685 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0240525 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0240216 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0239561 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0238897 |
