| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Epirubicin (hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Epirubicin (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.136828 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.11521 |
| RPS2 | ribosomal protein S2 | 0.101544 |
| FAT1 | FAT atypical cadherin 1 | 0.0939597 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0807532 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0786813 |
| RPS12 | ribosomal protein S12 | 0.0751409 |
| PKP2 | plakophilin 2 | 0.0695197 |
| RPL4 | ribosomal protein L4 | 0.067486 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0626464 |
| RPS3 | ribosomal protein S3 | 0.0576876 |
| TXNRD1 | thioredoxin reductase 1 | 0.0567529 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0522088 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.050039 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0480512 |
| MKI67 | marker of proliferation Ki-67 | 0.0475095 |
| GOLGA4 | golgin A4 | 0.0468219 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0460781 |
| FOXO1 | forkhead box O1 | 0.043377 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.042984 |
| FLNB | filamin B, beta | 0.0416317 |
| MUC13 | mucin 13, cell surface associated | 0.040774 |
| PLAC8 | placenta-specific 8 | 0.0392182 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0387662 |
| ABHD17C | abhydrolase domain containing 17C | 0.0386482 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.038484 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0378382 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0376844 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0372939 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0372665 |
| RPL21 | ribosomal protein L21 | 0.0361654 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0348565 |
| EGR1 | early growth response 1 | 0.0340806 |
| RPL18 | ribosomal protein L18 | 0.0336141 |
| RPS17 | ribosomal protein S17 | 0.0331614 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0331207 |
| ITGB4 | integrin, beta 4 | 0.0330383 |
| RPS19 | ribosomal protein S19 | 0.032686 |
| PRELID2 | PRELI domain containing 2 | 0.0322387 |
| RPS29 | ribosomal protein S29 | 0.0319935 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0318519 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0316916 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0309942 |
| PRSS3 | protease, serine, 3 | 0.0307878 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0299763 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0298767 |
| RPL5 | ribosomal protein L5 | 0.0298718 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.029121 |
| RAD51B | RAD51 paralog B | 0.0290682 |
| TRIM31 | tripartite motif containing 31 | 0.0290659 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0288738 |
| ITGA6 | integrin, alpha 6 | 0.0285218 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0284692 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0284684 |
| CENPF | centromere protein F, 350/400kDa | 0.028415 |
| RPS16 | ribosomal protein S16 | 0.0282597 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0280174 |
| YBX3 | Y box binding protein 3 | 0.0279689 |
| ZNF292 | zinc finger protein 292 | 0.0279337 |
| RPS8 | ribosomal protein S8 | 0.0275654 |
| TMF1 | TATA element modulatory factor 1 | 0.0275262 |
| RPL10A | ribosomal protein L10a | 0.027351 |
| PCDHB16 | protocadherin beta 16 | 0.0268791 |
| RPL37A | ribosomal protein L37a | 0.0266278 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0264717 |
| RPL13A | ribosomal protein L13a | 0.0262909 |
| FHL2 | four and a half LIM domains 2 | 0.0261128 |
| DUSP4 | dual specificity phosphatase 4 | 0.0256889 |
| ASPH | aspartate beta-hydroxylase | 0.0253916 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0253003 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0244545 |
| RPL36 | ribosomal protein L36 | 0.0243741 |
| BCL2L1 | BCL2-like 1 | 0.0240871 |
| TLN2 | talin 2 | 0.0240582 |
| ANLN | anillin, actin binding protein | 0.023721 |
| RACK1 | receptor for activated C kinase 1 | 0.0231618 |
| RPL12 | ribosomal protein L12 | 0.0230971 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0230288 |
| AUTS2 | autism susceptibility candidate 2 | 0.0229148 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0228462 |
| RPS23 | ribosomal protein S23 | 0.0227476 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0227224 |
| SERF2 | small EDRK-rich factor 2 | 0.0224558 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0218048 |
| RPL32 | ribosomal protein L32 | 0.0215733 |
| RNF145 | ring finger protein 145 | 0.0214993 |
| RPL28 | ribosomal protein L28 | 0.0213763 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0213026 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.021296 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0212954 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.021163 |
| RPLP2 | ribosomal protein, large, P2 | 0.0207467 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.020662 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0206249 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.020279 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0201175 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0200815 |
| H1-4 | H1.4 linker histone, cluster member | 0.0196795 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0196038 |
| EP400 | E1A binding protein p400 | 0.0195494 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.182521 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.126165 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.108786 |
| RPLP1 | ribosomal protein, large, P1 | -0.102153 |
| LMO7 | LIM domain 7 | -0.099126 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0966616 |
| MYO1E | myosin IE | -0.0914253 |
| CANX | calnexin | -0.0901257 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0901102 |
| RPLP0 | ribosomal protein, large, P0 | -0.0867397 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0842838 |
| FRMD5 | FERM domain containing 5 | -0.0805375 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0782653 |
| LDHA | lactate dehydrogenase A | -0.0780983 |
| FBXO11 | F-box protein 11 | -0.0698628 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0690343 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.064923 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.064331 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0641199 |
| PKM | pyruvate kinase, muscle | -0.0591047 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0574903 |
| RPL35A | ribosomal protein L35a | -0.0552475 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0549871 |
| HLA-B | major histocompatibility complex, class I, B | -0.0548931 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0548607 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0523617 |
| ANXA2 | annexin A2 | -0.0499706 |
| OXSR1 | oxidative stress responsive 1 | -0.0499634 |
| SP100 | SP100 nuclear antigen | -0.0481542 |
| INTS6 | integrator complex subunit 6 | -0.0479968 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0477862 |
| KRT18 | keratin 18, type I | -0.0460995 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0458098 |
| RPL34 | ribosomal protein L34 | -0.0449711 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0443963 |
| PALLD | palladin, cytoskeletal associated protein | -0.0407738 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0398329 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0389136 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0381658 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0376592 |
| UBAP2 | ubiquitin associated protein 2 | -0.0374438 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0358597 |
| LRRC23 | leucine rich repeat containing 23 | -0.0354976 |
| ACTG1 | actin gamma 1 | -0.0354651 |
| SERINC5 | serine incorporator 5 | -0.0351123 |
| TJP1 | tight junction protein 1 | -0.0348374 |
| RIGI | RNA sensor RIG-I | -0.0348141 |
| RPS24 | ribosomal protein S24 | -0.034794 |
| RPS20 | ribosomal protein S20 | -0.0344059 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0339983 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.033516 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0334407 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.033383 |
| MYO5B | myosin VB | -0.0332521 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0327849 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0321888 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.03182 |
| CUX1 | cut-like homeobox 1 | -0.0315638 |
| UBC | ubiquitin C | -0.0313971 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0313409 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0311036 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0308096 |
| HLA-E | major histocompatibility complex, class I, E | -0.0306151 |
| FUS | FUS RNA binding protein | -0.0303979 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0300445 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0299075 |
| DSPP | dentin sialophosphoprotein | -0.029558 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0294649 |
| NPSR1 | neuropeptide S receptor 1 | -0.0294626 |
| DIAPH1 | diaphanous-related formin 1 | -0.0294413 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0293897 |
| MORF4L2 | mortality factor 4 like 2 | -0.0290604 |
| RPL39 | ribosomal protein L39 | -0.0286341 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0284678 |
| S100A6 | S100 calcium binding protein A6 | -0.0280453 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.027967 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.027767 |
| RPL23 | ribosomal protein L23 | -0.0277053 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0276496 |
| KRT8 | keratin 8, type II | -0.0273203 |
| TC2N | tandem C2 domains, nuclear | -0.0271216 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0270323 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0268672 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0268573 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0268007 |
| MED13L | mediator complex subunit 13-like | -0.0267266 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0266493 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0264603 |
| VDAC1 | voltage-dependent anion channel 1 | -0.026394 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0262398 |
| ACTN4 | actinin, alpha 4 | -0.0261853 |
| TPM4 | tropomyosin 4 | -0.0259787 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0259055 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0257967 |
| SPAG9 | sperm associated antigen 9 | -0.0257828 |
| IRF1 | interferon regulatory factor 1 | -0.0256627 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0255453 |
| EPCAM | epithelial cell adhesion molecule | -0.02551 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0253126 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0251061 |
